Disclosed herein are multi-mode methods and devices for sample generation. An exemplary device for generating an output sample includes an analog-to-digital converter (ADC) for sampling a plurality of input analog signals and producing an ADC output sample. The ADC may include a ADC digital modulator including timing-critical components. A plurality of digital blocks may be coupled to the ADC digital modulator. The exemplary device may include a baseband processor for controlling a plurality of clock inputs. The plurality of clock inputs may drive the ADC digital modulator and the plurality of digital blocks. The baseband processor may be configured to operate in a plurality of modes including a first mode and a second mode. The first mode may include a first mode standby state and a first mode initial operating state. The second mode may include a second mode initial operating state and a second mode standby state.

Systems, apparatus, and methods are disclosed for conveying signals between a patient and monitoring and treatment devices. An EP system provides large-signal input protection and RF ablation signal noise suppression while preserving the integrity of relevant components of small signals. The EP system has a low-noise amplifier topology with minimal hardware filtering. An input protection circuit shunts to ground signals with amplitude above an ablation voltage. An RF filter circuit linearly attenuates the signals between 300 kHz and 600 kHz. A low-frequency feedback circuit drives a common mode node of the RF filter circuit for additional attenuation. A signal amplification circuit amplifies the signals between 0.01 Hz and 1000 Hz. A fast recovery circuit feeds back a low-frequency voltage signal to the signal amplification circuit to gradually reduce offset voltage of the signals. A high-resolution A/D converter converts the signals from the signal amplification circuit to clean digital signals.

Systems, apparatus, and methods are disclosed for conveying signals between a patient and monitoring and treatment devices. An EP system provides large-signal input protection and RF ablation signal noise suppression while preserving the integrity of relevant components of small signals. The EP system has a low-noise amplifier topology with minimal hardware filtering. An input protection circuit shunts to ground signals with amplitude above an ablation voltage. An RF filter circuit linearly attenuates the signals between 300 kHz and 600 kHz. A low-frequency feedback circuit drives a common mode node of the RF filter circuit for additional attenuation. A signal amplification circuit amplifies the signals between 0.01 Hz and 1000 Hz. A fast recovery circuit feeds back a low-frequency voltage signal to the signal amplification circuit to gradually reduce offset voltage of the signals. A high-resolution A/D converter converts the signals from the signal amplification circuit to clean digital signals.

Systems, apparatus, and methods are disclosed for bi-directionally conveying biomedical signals between a patient and signal acquisition and processing devices. An electrophysiology (EP) system includes an analog input protection and filtering stage with a differential circuit to process the biomedical signals to and from the patient; a signal amplification stage with a differential amplifier circuit to amplify an output of the differential circuit; an analog-to-digital converter stage to digitize an output of the differential amplifier circuit; a communication module to interface between the analog-to-digital converter stage and a digital processing stage having a plurality of signal modules; at least one processor to execute the plurality of signal modules, applying frequency-selective filtering and signal processing algorithms to the output from the analog-to-digital converter stage, to extract high-frequency and low-amplitude features of the biomedical signals in frequency ranges of interest; and a display for pattern- and time-aligned visualization of the biomedical signals.

Systems, apparatus, and methods are disclosed for bi-directionally conveying biomedical signals between a patient and signal acquisition and processing devices. An electrophysiology (EP) system includes an analog input protection and filtering stage with a differential circuit to process the biomedical signals to and from the patient; a signal amplification stage with a differential amplifier circuit to amplify an output of the differential circuit; an analog-to-digital converter stage to digitize an output of the differential amplifier circuit; a communication module to interface between the analog-to-digital converter stage and a digital processing stage having a plurality of signal modules; at least one processor to execute the plurality of signal modules, applying frequency-selective filtering and signal processing algorithms to the output from the analog-to-digital converter stage, to extract high-frequency and low-amplitude features of the biomedical signals in frequency ranges of interest; and a display for pattern- and time-aligned visualization of the biomedical signals.

Apparatus and methods remove a voltage offset from an electrical signal, specifically a biomedical signal. A signal is received at a first operational amplifier and is amplified by a gain. An amplitude of the signal is monitored, by a first pair of diode stages coupled to an output of the first operational amplifier, for the voltage offset. The amplitude of the signal is then attenuated by the first pair of diode stages and a plurality of timing banks. The attenuating includes limiting charging, by the first pair of diode stages, of the plurality of timing banks and setting a time constant based on the charging. The attenuating removes the voltage offset persisting at a threshold for a duration of at least the time constant. Saturation of the signal is limited to a saturation recovery time while the saturated signal is gradually pulled into monitoring range over the saturation recovery time.

Apparatus and methods remove a voltage offset from an electrical signal, specifically a biomedical signal. A signal is received at a first operational amplifier and is amplified by a gain. An amplitude of the signal is monitored, by a first pair of diode stages coupled to an output of the first operational amplifier, for the voltage offset. The amplitude of the signal is then attenuated by the first pair of diode stages and a plurality of timing banks. The attenuating includes limiting charging, by the first pair of diode stages, of the plurality of timing banks and setting a time constant based on the charging. The attenuating removes the voltage offset persisting at a threshold for a duration of at least the time constant. Saturation of the signal is limited to a saturation recovery time while the saturated signal is gradually pulled into monitoring range over the saturation recovery time.

Systems, methods, and computer program product embodiments are disclosed for processing and displaying multiple signals in near real-time. An embodiment operates by processing, using a first digital signal processor (DSP) of a first signal module, a first packet associated with a first signal. The embodiment also processes, using a second DSP of a second signal module, a second packet associated with a second signal. The embodiment equalizes a first processing delay associated with the first DSP with a second processing delay associated with the second DSP such that the first DSP completes processing of the first packet approximately simultaneously with the second DSP completing processing of the second packet. The embodiment then displays the processed first packet approximately simultaneously with the display of the processed second packet.

Systems, methods, and computer program product embodiments are disclosed for processing and displaying multiple signals in near real-time. An embodiment operates by processing, using a first digital signal processor (DSP) of a first signal module, a first packet associated with a first signal. The embodiment also processes, using a second DSP of a second signal module, a second packet associated with a second signal. The embodiment equalizes a first processing delay associated with the first DSP with a second processing delay associated with the second DSP such that the first DSP completes processing of the first packet approximately simultaneously with the second DSP completing processing of the second packet. The embodiment then displays the processed first packet approximately simultaneously with the display of the processed second packet.

An aspect includes a filtering method including operating a first filter to filter a first input signal to generate a first output signal; operating a second filter to filter a second input signal to generate a second output signal; and selectively coupling at least a portion of the second filter with the first filter to filter a third input signal to generate a third output signal. Another aspect includes a filtering method including operating switching devices to configure a filter with a first set of pole(s); filtering a first input signal to generate a first output signal with the filter configured with the first set of pole(s); operating the switching devices to configure the filter with a second set of poles; and filtering a second input signal to generate a second output signal with the filter configured with the second set of poles.