Disclosed herein are compositions and methods for treating cancer in a subject. This involves administering an oncolytic virus containing a heterologous DNA sequence encoding one or more immunomodulatory and/or immunostimulatory polypeptide(s) of interest to the subject under conditions effective to enhance an anti-tumor immune response in the subject, and to treat cancer. It also relates to a method of enhancing the delivery to and distribution within a tumor mass of therapeutic viruses.

In some embodiments, a supervising electronic device manages communication restrictions of a supervised electronic device. In some embodiments, a supervised electronic device presents user interfaces that enforce one or more communication restrictions configured by a supervising electronic device when communicating with other users.

The disclosed systems and techniques enable an enterprise system to store contact phone numbers for users while avoiding storing and managing personal phone numbers for the user. For example, the enterprise system may forward personal phone numbers to an aliasing server configured to (i) generate alias phone numbers based on the personal email addresses and (ii) provide the alias phone numbers to the enterprise system. The aliasing server may operate as a “middle man” that receives phone calls or text messages directed to the alias phone numbers and that forwards the phone calls or text messages to the corresponding personal phone numbers (when appropriate). The enterprise system may store and maintain the alias phone numbers in lieu of storing the personal email addresses.

A redirection and messaging system receives telephony information identifying a caller and call context from a telephony system. The system selects one of a plurality of messaging operators based on the call context, optionally sends an introductory message to the caller via a messaging service, and generates a message interface for the selected message operator. The message interface includes the caller and call context and any messages sent between the caller and the selected message operator, with an input interface allowing the selected message operator to input and send messages to the caller.

Systems and methods for smart dialogue communication are provided. A method may include receiving, from a responder terminal device, a dialogue request configured to request a smart dialogue communication, wherein the dialogue request is associated with an incoming call request that is initiated by a requester via a requester terminal device and satisfies a smart dialogue condition determined by the responder terminal device; performing the smart dialogue communication with the requester terminal device associated with the requester; recording voice information associated with the smart dialogue communication; converting the voice information into the text information; and transmitting the text information to the responder terminal device.

One example method of operation may include one or more of identifying an incoming communication via a communication processing device, identifying communication source attributes associated with a communication source of the incoming communication, retrieving one or more communication routing conditions from a communication recipient profile associated with an intended recipient device identified by the incoming communication, and determining whether to route the incoming communication to the intended recipient device or an automated communication management device based on the communication source attributes and the one or more communication routing conditions.

Techniques for determining a global state for multiple related calls are disclosed. A first call between a first device and a second device is established, where the first call is assigned a user call identifier. A second call between the first device and a third device is established. A shared call operation is established by assigning the user call identifier to the second call. The user call identifier is assigned to the second call in addition to already being assigned to the first call. A first status of the first call and a second status of the second call are determined. The first status and the second status are used to determine a global state of the shared call operation. The global state of the shared call operation is updated in response to one or both of the first status or the second status changing.

One example method of operation may include one or more of identifying an incoming communication via a communication processing device, identifying communication source attributes associated with a communication source of the incoming communication, retrieving one or more communication routing conditions from a communication recipient profile associated with an intended recipient device identified by the incoming communication, and determining whether to route the incoming communication to the intended recipient device or an automated communication management device based on the communication source attributes and the one or more communication routing conditions.

A system comprises an applications server configured to communicatively couple to a softswitch, a resource server, and a database. The applications server is configured to receive, from the softswitch, an indication that a call from a calling party directed to a called number was received and determine, in response to the indication that the call was received, whether to route the call to an available agent or to a speech-enabled intelligent script associated with one of the called number or the calling party. The applications server is configured to instruct the softswitch to route the call to the speech-enabled intelligent script in response to a determination to route the call to the speech-enabled intelligent script. The applications server is configured to instruct the softswitch to route the call to the available agent in response to a determination to route the call to the available agent.

Systems and methods for smart dialogue communication are provided. A method may include receiving, from a responder terminal device, a dialogue request configured to request a smart dialogue communication, wherein the dialogue request is associated with an incoming call request that is initiated by a requester via a requester terminal device and satisfies a smart dialogue condition determined by the responder terminal device; performing the smart dialogue communication with the requester terminal device associated with the requester; recording voice information associated with the smart dialogue communication; converting the voice information into the text information; and transmitting the text information to the responder terminal device.