An image reading device generates, as image data of a reading region, image data for output and image data for size detection, the latter having a lower resolution than the former, discriminates high density lines from the size-detection image data, sets as a target line one of the high density lines. And the image reading device calculates as a width for size detection a width from a reference line to the target line, sets as the size of a document a reference size that has a width closest to the width for size detection, performs image processing on the output image data based on the reference size set as the size of the document, and outputs the processed image data.

An image reading apparatus includes a movable body supported so as to be movable along a support table, the movable body supporting at least a light source; a controller that controls the light source; a connection member that electrically connects the movable body and the controller together, the connection member formed into a strip shape whose longitudinal direction extends in a direction in which the movable body moves and whose lateral direction extends in a widthwise direction, the connection member including a folded-back portion that is folded back in a direction opposite to the direction in which the movable body moves; and a guide member disposed along the connection member, the guide member having a high flexural rigidity in a portion that extends along the direction in which the movable body moves, the guide member having a low flexural rigidity in a portion corresponding to the folded-back portion.

The present invention relates to novel linear and cyclic polypeptides that bind to IL-23 receptor and inhibit the binding of IL-23 to its corresponding receptor and cell signaling thereof. The novel polypeptides of the present invention has a core structure of WX.sub.1X.sub.2X.sub.3W, where W is tryptophan, and X.sub.1, X.sub.2 and X.sub.3 are amino acids, with the proviso that when one of X.sub.1, X.sub.2 or X.sub.3 is W, the remaining two of X.sub.1, X.sub.2 or X.sub.3 cannot be W. Preferred core structures include WVDYW or WQDYW. The present invention relates a composition containing the novel polypeptides (linear or cyclic), and use of same in inhibiting cell functions including production of IL-22 and IL-17F from immune cells as well as in treating IL-23 associated human diseases including, for example, inflammatory bowel diseases, psoriasis and Crohn's disease, ulcerative colitis and multiple sclerosis.

An apparatus may include a transparent platen, a command interface, a scanner unit, a controller and an indicator. The command interface is to receive externally originating instructions including a selected scaling value, other than 100%, for a scanning operation of a document resting against the transparent platen, wherein contents of the document to be scanned are proportionally magnified or shrunk based on the selected scaling value The controller controls a scanner unit to capture a portion of the transparent platen, the portion having borders automatically determined and proportionally changed by the controller based upon the selected scaling value. The indicator provides a visible indication of the portion.

An image processing apparatus includes a support member to support a sheet, a light source that extends in a main-scanning direction and is configured to move in a sub-scanning direction and irradiate light on the sheet as the light source moves in the sub-scanning direction, a conversion unit configured to generate multiple line image data based on light reflected by the sheet and incident thereon, as the light source moves in the sub-scanning direction, and a processing unit configured to carry out a correction process with respect to each of the line image data using a different correction formula for each of the line image data.

A blast mechanism in an image reading apparatus reliably cools heat generated in boards by a blast path with high cooling action among a plurality of boards disposed inside a casing. A partition plate is disposed between a plurality of boards disposed at a distance away in a layered shape, a first blast path is formed between a top of the casing and a first board, a second blast path is formed between the first board and the partition plate, a third blast path is formed between the partition plate and a second board, and a flow of cooling air is formed in each blast path with a blast fan. A blast mechanism for sending cooling air includes the casing, first and second boards disposed vertically inside the casing, the partition plate disposed between the first board and the second board, and fans for sending cooling air.

A scanner is disclosed. The scanner has a platen with at least one edge of the platen uncovered.

An image reading apparatus includes a reader that reads an image of a document by using plural light receiving elements arranged in a first scanning direction; a moving unit that moves the reader in a second scanning direction to move a reading position at which the reader reads the document; and an adjusting unit that moves the reader in the first scanning direction to adjust a position of the reader in the first scanning direction.

An image processing apparatus includes a support member to support a sheet, a light source that extends in a main-scanning direction and is configured to move in a sub-scanning direction and irradiate light on the sheet as the light source moves in the sub-scanning direction, a conversion unit configured to generate multiple line image data based on light reflected by the sheet and incident thereon, as the light source moves in the sub-scanning direction, and a processing unit configured to carry out a correction process with respect to each of the line image data using a different correction formula for each of the line image data.

Various embodiments and methods relating to a scan area indicator are disclosed.