An imaging device with low power consumption is provided. It includes a pixel capable of outputting difference data between two different frames, a circuit determining the significance of the difference data, a circuit controlling power supply, an A/D converter, and the like; obtains image data and then obtains difference data; and shuts off power supply to the A/D converter and the like in the case where it is determined that there is no difference, and continues or restarts the power supply to the A/D converter and the like when it is determined that there is a difference. Determining the significance of the difference data can be performed row by row in a pixel array or at nearly the same time in all the pixels included in the pixel array.

Radiation imaging apparatus includes pixel array having pixels, readout circuit for reading signals from the pixel array, and detector for detecting, based on radiation emitted from radiation source or information provided from the radiation source, start of radiation irradiation by the radiation source, and controller for determining timing of each of operations of sample and hold in each of the pixels each time the start of radiation irradiation is detected by the detector. The timing of at least one operation of the operations is timing in radiation irradiation period, and each of the pixels includes convertor for converting radiation into electrical signal, and sample and hold circuit for sample-holding the signal from the conversion element over plural times in accordance with the timing of each of the operations determined by the controller.

A radiation imaging apparatus is provided. The apparatus includes an imaging unit including pixels and a control unit. Each of the pixels includes a conversion unit and a sample/hold circuit. The control unit causes the imaging unit to perform first imaging and second imaging after the first imaging to generate one energy subtraction image, and controls a timing of causing the sample/hold circuit in the first imaging to sample a first image signal obtained by the first imaging and a timing of causing the sample/hold circuit in the second imaging to sample a second image signal obtained by the second imaging in accordance with radiation irradiation conditions set in advance so as to reduce a difference between an amount of noise contained in the first image signal and an amount of noise contained in the second image signal.

A radiation counting device is provided that includes a scintillator, a pixel circuit, and an analog-to-digital conversion circuit. In the radiation counting device, the scintillator generates a photon when radiation is incident. In the radiation counting device, the pixel circuit converts the photon into charge, stores the charge over a predetermined period, and generates an analog voltage in accordance with the amount of stored charge. In the radiation counting device, the analog-to-digital conversion circuit converts the analog voltage into a digital signal in a predetermined quantization unit less than the analog voltage generated from the one photon.

Disclosed is a radiographic imaging system including: radiation detecting elements that is two-dimensionally arrayed; and an image acquiring circuit that acquires an image by causing the radiation detecting elements to accumulate and release charges and reading the released charges, wherein the radiographic imaging system comprises a hardware processor that: controls the image acquiring circuit to successively acquire radiographs while changing at least a binning number; controls the image acquiring circuit to acquire offset images respectively for the radiographs in which a binning number in resetting the radiation detecting elements before acquiring the offset images and binning numbers in acquiring the offset images are equal respectively to a binning number in resetting the radiation detecting elements before acquiring the radiographs and binning numbers in acquiring the radiographs; and performs an offset correction on the radiographs by using the offset images respectively for the radiographs.

An imaging device with low power consumption is provided. It includes a pixel capable of outputting difference data between two different frames, a circuit determining the significance of the difference data, a circuit controlling power supply, an A/D converter, and the like; obtains image data and then obtains difference data; and shuts off power supply to the A/D converter and the like in the case where it is determined that there is no difference, and continues or restarts the power supply to the A/D converter and the like when it is determined that there is a difference. Determining the significance of the difference data can be performed row by row in a pixel array or at nearly the same time in all the pixels included in the pixel array.

A microscopic imaging method, includes illuminating a specimen with illumination radiation and capturing detection radiation along a detection axis. The detection radiation is caused by the illumination radiation, at a first time as a wide-field signal and at a second time as a composite signal. The composite signal is formed by a superposition of a confocal image and a wide-field image; extracting the confocal image by subtracting the wide-field signal from the composite signal, wherein a correction factor is used. A current correction factor is ascertained for each executed imaging and/or for each imaged specimen (1) and the confocal image is extracted using the respective current correction factor.

A radiation counting device is provided that includes a scintillator, a pixel circuit, and an analog-to-digital conversion circuit. In the radiation counting device, the scintillator generates a photon when radiation is incident. In the radiation counting device, the pixel circuit converts the photon into charge, stores the charge over a predetermined period, and generates an analog voltage in accordance with the amount of stored charge. In the radiation counting device, the analog-to-digital conversion circuit converts the analog voltage into a digital signal in a predetermined quantization unit less than the analog voltage generated from the one photon.

An imaging control apparatus obtains a plurality of images at different radiation energies, the images having been obtained as a result of irradiating a subject with radiation whose energy changes during one shot, and detecting, a plurality of times, the radiation that has passed through the subject during the one shot; generates an energy subtraction image by performing energy subtraction processing using a plurality of images; and generates a difference image using a plurality of generated energy subtraction images.

A radiation imaging apparatus includes an imaging unit having a pixel array of pixels, and a signal processing unit for processing a signal from the imaging unit. Each pixel includes a conversion element for converting radiation into electrical signal and a reset unit for resetting the conversion element, the signal processing unit generates radiation image based on first image corresponding to electrical signal converted by the conversion unit of each pixel in a first period, and second image corresponding to electrical signal converted by the conversion element of each pixel in a second period which starts after start of the first period and ends before end of the first period, and in each pixel, the conversion element is not reset by the reset unit in the first period.