An apparatus for use with a neutron source for producing reaction-product nuclei from reactant nuclei includes a plurality of reactant nuclei and a plurality of moderating nuclei. The reactant nuclei and the moderating nuclei are configured to increase the probability of neutron capture by reactant nuclei to achieve enhanced ratios of neutron capture by reactant nuclei to neutron source neutron production. Moderating nuclei and neutron reflection are used to minimize neutron leakage. Temperature control, including cryogenic temperature control, may be used to enhance the rate or probability of reactant nuclei neutron capture. The reactant nuclei may include molybdenum-98 and reaction-product nuclei may include technetium-99m.

A method of irradiating a target with a high power density irradiation beam is described. The method can use an irradiation system configured to output an irradiation beam through a vacuum window. The irradiation beam is scanned repetitively back and forth between two angular orientations of the irradiation beam as the irradiation beam strikes and traverses the vacuum window. The target is moved as the irradiation beam is scanned. The irradiation beam and the target are aligned. The scanning of the irradiations beam and the moving of the target are synchronized to each other. The scanning of the irradiation beam prevents localized overheating of the vacuum window and allows the irradiation beam to have a power density that would damage the vacuum window if the irradiation beam were not scanned.

A continuous wave ion linear accelerator PET radioisotope system is disclosed. The system includes a high brightness H.sup. ion source, a continuous wave RF quadrupole structure, and continuous wave RF interdigital structures to accelerate the ion beam to about 14 MeV. A high energy beam transport system is also described that includes a photo-detachment beam splitter and a magnet lattice for forming the proton beam into a beam having a Waterbag beam profile. The system also includes one or more targets upon which the proton beam is incident. The targets are either a high power metallic target oriented at about 10 degrees or a low thermal conductivity target oriented at about 35 degrees. The invention includes a method of producing PET isotopes by use of the systems described.

A method of irradiating a target with a high power density irradiation beam is described. The method can use an irradiation system configured to output an irradiation beam through a vacuum window. The irradiation beam is scanned repetitively back and forth between two angular orientations of the irradiation beam as the irradiation beam strikes and traverses the vacuum window. The target is moved as the irradiation beam is scanned. The irradiation beam and the target are aligned. The scanning of the irradiations beam and the moving of the target are synchronized to each other. The scanning of the irradiation beam prevents localized overheating of the vacuum window and allows the irradiation beam to have a power density that would damage the vacuum window if the irradiation beam were not scanned.

A beam accelerator system operable to produce a medical isotope, including an ion accelerator that generates an ion beam; a low-pressure chamber; an anode adjacent and fluidly connected to the low-pressure chamber; a plasma window adjacent and fluidly connected to the anode; and a cathode housing adjacent and fluidly connected to the plasma window. The plasma window has a plurality of plates, each plate having an aperture that is aligned with an aperture in one or more adjacent plates to form a plasma channel. One or more plates in the plurality of plates includes a unitary plate having an aperture therein, and one or more cooling channels entering the unitary plate at a first side of the unitary plate and exiting the unitary plate at a second side of the unitary plate. The one or more cooling channels run through a thickness of the unitary plate.

Systems and methods that facilitate the transmutation of long-lived radioactive transuranic waste into short-live radioactive nuclides or stable nuclides using an electrostatic accelerator particle beam to generate neutrons.

An apparatus for generating medical isotopes provides an annular fissile solution vessel surrounding a neutron generator. The annular fissile solution vessel provides for good capture of the emitted neutrons and a geometry that provides enhanced stability in an aqueous reactor. A neutron multiplier and/or a neutron moderator may be used to improve the efficiency and control the criticality of the reaction in the annular fissile solution vessel.

A radioisotope production apparatus includes a particle accelerator, a first target portion on which a charged particle beam emitted from the particle accelerator is incident and through which the charged particle beam passes, and a second target portion on which the charged particle beam passing through the first target portion is incident. In the first target portion, a target material is held in a beam passage, and a cooling gas supply unit which blows a cooling gas to the target material is provided. In a second target portion, a target substrate is held on a beam axis and a downstream-side surface of the target substrate with respect to the charged particle beam is cooled by cooling water. A total thickness of target foils of the first target portion on the beam axis is smaller than a thickness of the target substrate of the second target portion on the beam axis.

Radioisotope production system includes an electrical field system and a magnetic field system that are configured to direct a particle beam of charged particles along a beam path within an acceleration chamber. The magnetic field system is energized by a drive current to generate a magnetic flux into the acceleration chamber for controlling the particle beam. The radioisotope production system also includes a target system configured to hold a target material and receive the particle beam. The radioisotope production system also includes a monitoring system that is configured to: (a) determine an operating parameter of the radioisotope production system as the particle beam is directed toward the target material and (b) change the drive current, thereby changing the magnetic flux, based on the operating parameter.

An apparatus for generating medical isotopes provides an annular fissile solution vessel surrounding a neutron generator. The annular fissile solution vessel provides for good capture of the emitted neutrons and a geometry that provides enhanced stability in an aqueous reactor. A neutron multiplier and/or a neutron moderator may be used to improve the efficiency and control the criticality of the reaction in the annular fissile solution vessel.