A01N1/0215

Methods of Preserving Blood Samples for Mass Screening to Detect at-Risk Individuals for Autoimmune Diseases
20210140961 · 2021-05-13 ·

A method of screening an individual for an autoimmune disease comprising analyzing a blood sample, containing at least one biomarker, from an individual wherein the blood sample is suspended and preserved by a blood stabilizing solution and wherein the autoimmune disease is rheumatoid arthritis, celiac disease, systemic lupus erythematosus, or Sjogren's syndrome.

METHODS FOR COLLECTING AND PROCESSING AUTOGRAFTS, PROCESSED AUTOGRAFTS, KITS FOR COLLECTING AND TRANSPORTING AUTOGRAFTS, AND TOOLS FOR PREPARING AUTOGRAFTS

The present invention is directed to methods for collecting and processing autografts, processed autografts, kits for collecting and transporting autografts, and tools for preparing autografts. It is also directed to autologous bone grafts, and methods of preparing them.

MODIFIED DONOR ORGANS
20230404064 · 2023-12-21 ·

A repaired ex vivo organ suitable for transplantation in a human, said repaired ex vivo organ having undergone ex vivo organ perfusion for a maintenance period, wherein said organ had been assessed as being unsuitable for transplantation into a human before the maintenance period and was determined to be suitable for transplantation after the maintenance period.

COMPOSITION FOR REMOVING PHOSPHOLIPIDS AND CELL DEBRIS AND METHOD FOR REMOVING PHOSPHOLIPIDS AND CELL DEBRIS ON BIOLOGICAL TISSUE

Disclosed in the present application is a composition for removing phospholipids and cell debris, comprising an alcohol, an alcohol ether, and a surfactant, wherein the alcohol accounts for 50-90 wt %, preferably 60-80 wt %; the alcohol ether accounts for 5-40 wt %, preferably 10-20 wt %; the surfactant accounts for 0.1-5 wt %, preferably 1-3 wt %. The present application further provides a method for removing phospholipids and cell debris on biological tissue. The composition of the present application is used for treating biological tissue, and the treated biological tissue has an excellent anti-calcification effect.

Methods for collecting and processing autografts, processed autografts, kits for collecting and transporting autografts, and tools for preparing autografts

The present invention is directed to methods for collecting and processing autografts, processed autografts, kits for collecting and transporting autografts, and tools for preparing autografts. It is also directed to autologous bone grafts, and methods of preparing them.

Perfusion Loop Assembly for an Ex-Vivo Liver Perfusion and a Method for Ex-Vivo Liver Perfusion

A perfusion loop assembly for ex vivo liver perfusion includes a pump providing perfusion fluid through a line branching at a branching point into a first branch line and a second branch line. The first branch line provides a first portion of the perfusion fluid to the hepatic artery of the liver, the first branch line coupled with a gas exchanger, where the first branch line includes a flow rate sensor and/or a pressure sensor. The second branch line provides a second portion of the perfusion fluid to the portal vein of the liver; the second branch line includes a valve for controlling flow of perfusion fluid into the portal vein. The second branch line includes a flow rate sensor and/or a pressure sensor. A liver chamber assembly holds the liver ex vivo, and an outlet line for the perfusion fluid connects the liver chamber assembly and the pump.

MATERIALS AND METHODS FOR PROCESSING BLOOD SAMPLES
20200316498 · 2020-10-08 ·

Provided herein are materials and methods relating to cell-free DNA. In particular, the technology relates to methods and materials for the preparation and handling of blood samples for future use in applications involving cell-free DNA.

AQUEOUS COMPOSITION BASED ON POLYOXYMETHYLENE DIALKYL ETHERS (POM) AND THEIR USE FOR THE PRESERVATION AND/OR EMBALMING OF THE HUMAN OR ANIMAL BODY

The invention relates to a mixture of polyoxymethylene dialkyl ethers (POM) having a specific molecular distribution of n as well as its preparation method.

The invention also relates to a composition comprising: a) a mixture of polyoxymethylene dialkyl ethers (POM) having a restricted specific molecular distribution b) at least one biocidal agent c) at least one pro-penetrating agent d) at least one dye e) optionally, another additive
and water as diluent,

It also relates to a non-therapeutic method of preserving and/or embalming a dead human or animal body using the composition, such as the use of this composition for anatomopathological purposes.

AQUEOUS COMPOSITION BASED ON POLYOXYMETHYLENE DIALKYL ETHERS (POM) AND THEIR USE FOR THE PRESERVATION AND/OR EMBALMING OF THE HUMAN OR ANIMAL BODY

The invention relates to a composition comprising: a) a mixture of polyoxymethylene dialkyl ethers (POM) having a restricted specific molecular distribution b) at least one biocidal agent c) at least one pro-penetrating agent d) at least one dye e) optionally, another additive and water as diluent.

It also relates to a non-therapeutic method of preserving and/or embalming a dead human or animal body using the composition, such as the use of this composition for anatomopathological purposes.

DETOXIFICATION AND STABILIZATION OF IMPLANTABLE OR TRANSPLANTABLE BIOLOGICAL MATERIAL

This invention relates to method of detoxification and stabilization of implantable or transplantable biological material of human or animal origin, the method including the following steps: treatment of the material with an antibiotic solution containing at least one antifungal agent/s; treatment of the material in a solution containing an organic acid surfactant bile acid; treatment of the material in a solution to remove the organic acid surfactant bile acid; and treatment of the material in a primary alcohol such as ethanol. The solution containing an organic acid surfactant bile acid contains a synergistic triple combination of the organic acid surfactant bile acid, an anionic surfactant, and a non-ionic surfactant.