The present invention is directed to methods for collecting and processing autografts, processed autografts, kits for collecting and transporting autografts, and tools for preparing autografts. It is also directed to autologous bone grafts, and methods of preparing them.

The kit for collection of umbilical cord, umbilical cord blood and placenta includes a collection case and a case cover hinged with the collection case. A tool box, a refrigeration box and a freezing box are arranged in the collection case. A liner plate is arranged in the tool box and provided with an accommodating trough, at least three storage troughs and several test tube troughs. An umbilical cord collection box, a placenta collection box and a blood collection bag are respectively arranged in the three storage troughs. A reagent bottle for containing a cell protection solution is arranged in the refrigeration box. Several ice bags are arranged in the freezing box.

The present invention provides pathogen-inactivated red blood cell compositions.

The present invention provides pathogen-inactivated red blood cell compositions.

A preservation solution for corneal tissues in vitro includes: approximately 0.05%-15% by weight/volume of a culture medium for biological tissues, approximately 0.05%-20% by weight/volume of at least one polymer compound having oncotic properties and a Mean molecular weight between 5000 and 550000 Dalton, and approximately 0.05%-5% by weight/volume of at least one nutrient protein, which is a uniquely synthetic origin.

The preservation solution being suitable for preserving the corneal tissues at a temperature between approximately +2? C. and approximately +37? C. and for a preservation period up to 4 weeks, maintaining the vitality of the corneal cells in a substantially unchanged state and the corneal thickness in a substantially physiological state during the preservation period at temperatures between approximately +2? C. and approximately +37? C.

Provided are systems and methods for treating a biological fluid, e.g., to inactivate pathogens.

Methods for denucleation of biological tissue. A method of denucleating biological tissue can include exposing a target tissue to at least one hyperosmotic solution and at least one hypoosmotic solution in an alternating fashion, and then applying a glutaraldehyde solution to the target tissue to fix the extracellular matrix and cytoskeleton of the target tissue.

This disclosure relates to methods of preserving mesenchymal stromal/stem cells (MSCs) for use in clinical applications. In certain embodiments, this disclosure relates to methods of preserving MSCs comprising mixing MSCs with interferon-gamma prior to cryopreserving, freezing, or cooling the MSCs to a temperature below zero degrees Celsius.

There is provided a method or improving the surface sterility of an invertebrate organism having an external cuticle, comprising contacting an outer surface of the organism, or a portion thereof, with an aqueous alcohol solution of less than about 70% v/v for a period of less than 60 seconds. The method is especially useful to provide research-grade organisms which can be utilised in research involving injection of compositions through the external cuticle, by reducing phenotype changes resulting from introduction of surface contaminants into the interior of the organism.

Provided are methods, kits, and compositions for preparing platelet compositions suitable for infusion, including improved methods, compositions, and kits for pathogen inactivation of an apheresis-derived preparation of platelets.