An apparatus for storing an organ or body tissue is disclosed, comprising: a container unit comprising a container body defining a storage region, wherein the container body includes an opening to enable the organ or body tissue to be admitted to, and removed from, the storage region; and a surgical drape (802) comprising: a securing portion (804) which is securable to the container unit, a peripheral outer portion (808) which surrounds the securing portion, and a frangible portion (810) separating the securing portion from the peripheral outer portion; wherein the securing portion is securable to the container body to enable the drape to extend around a portion of the periphery of the opening with the peripheral outer portion of the drape arranged outward of the opening; and wherein the frangible portion extends around the securing portion to enable the peripheral outer portion to be separated from the securing portion by tearing the frangible portion.

Methods and apparatus use low temperature and elevated pressure to depress the freezing and melting temperature of water and aqueous solutions, to induce suspended animation in materials including but not limited to biological material, soluble molecules, organic and inorganic compounds. Disposing such materials in a pressure vessel and increasing the pressure to about 210 MPa depresses the freezing and melting temperature of water, biological matter, and materials in aqueous solution, to about −22° C. Storage at low temperature under high pressure suspends metabolic activity and induces cryostasis. The methods and apparatus may be used for cryo-banking biological materials that cannot be frozen or vitrified, or otherwise preserved, including, but not limited to, cells, tissues, human organs for transplantation, and entire organisms.

The invention is directed to an energy efficient thermoelectric heat pump assembly. The thermoelectric heat pump assembly preferably includes two to nine thermoelectric unit layers capable of active use of the Peltier effect; and at least one capacitance spacer block suitable for storing heat and providing a delayed thermal reaction time of the assembly. The capacitance spacer block is thermally connected between the thermoelectric unit layers. The present invention further relates to a thermoelectric transport and storage devices for transporting or storing temperature sensitive goods, for example, vaccines, chemicals, biologicals, and other temperature sensitive goods. Preferably the transport or storage devices are configured and provide on-board energy storage for sustaining, for multiple days, at a constant-temperature, with an acceptable temperature variation band.

The present invention relates to a method of freezing of biological material and a freezing apparatus for freezing of biological material.

Compositions, methods and kits are described for stabilizing cells and biological samples, allowing for storage and transportation of stabilized cells and biological samples. Cells can be stabilized in whole blood or fractionated blood. Isolated cells can also be stabilized.

A living body specimen transport device for receiving multiple living body specimens has a frame, a rotating bracket, and a storage assembly. The rotating bracket can be rotated with respect to the frame. The storage assembly can receive a container with a living body specimen and be rotated with respect to the rotating bracket. A center of gravity of the storage assembly is lower than a pivoting point where the rotating bracket is mounted on the frame and a pivoting point where the storage assembly is mounted on the rotating bracket. With such structure, even when the living body specimen transport device is vibrated and shaken during transporting and then the frame of the living body specimen transport device is tilted or turned over, the rotating bracket and the storage assembly can rotate to be vertical by themselves, which keeps the living body specimen being soaked in the preservation solution.

A method and apparatus for freezing a liquid droplet includes dispensing, by a liquid dispenser, a droplet of liquid into a fluid chamber containing a freezing liquid. The droplet of liquid is allowed to dwell in the freezing liquid for at least a predetermined dwell time so that the droplet of liquid freezes to a frozen droplet. The method and apparatus further includes injecting, by a gas injector, a stream of gas transversely to a surface of the freezing liquid at about where the frozen droplet is located along the surface of the freezing liquid contained in the fluid chamber so that the frozen droplet sinks in the freezing liquid.

The present disclosure provides an organ supporting device and a manufacturing system thereof. The organ supporting device includes a tube with a one or more bends to create two supporting regions for an organ. The supporting regions are connected via a connecting region. The tube is supplied with temperature control material, such as a cooling fluid, by a circulation component. The temperature of the organ and fluid are sensed by one or more sensors and the sensed temperatures are provided to a temperature control unit to increase or decrease the temperature of the temperature control material to maintain a temperature of an organ for in-vivo or ex-vivo surgical procedures.

Disclosed herein are recellularized livers prepared from decellularized liver extracellular matrices. Also disclosed herein are kits and systems comprising a recellularized liver as described herein. Also disclosed herein are methods of recellularizing livers from decellularized liver extracellular matrices.

A shock absorbing device to protect cryogenically frozen biological material includes an outer sleeve and a foam sleeve. The outer sleeve defines an interior volume and has an opening configured to pass a biological material container into the interior volume. The foam sleeve is in the interior volume and has an opening and an interior cavity. The opening of the foam sleeve is aligned with the opening of the outer sleeve to pass the biological material container into the interior cavity. In another embodiment, the shock absorbing device includes a first layer, a foam layer, and a liner layer to retain the foam layer. A first side of the foam layer is adjacent and facing a second side of the first layer. A first side of the liner layer is adjacent and facing a second side of the foam layer.