A system comprises a fluid supply, a pressure regulator, a pressure valve, and a vent assembly. The fluid supply stores a volume of a fluid and is fluidly coupled to an outlet tube. The outlet tube is configured to be fluidly coupled to at least a portion of an organ environment. The organ environment configured to hold an organ. The pressure regulator is fluidly coupled to the outlet tube and is configured to maintain a fluid pressure of the fluid being supplied to the organ environment from the outlet tube. The fluid being supplied is at a pressure range above ambient to maintain the organ in an inflated position. The pressure valve is fluidly coupled to the outlet tube and inhibits increase of the fluid pressure above a threshold. The vent assembly removes excess fluid from the organ environment and includes a vent tube disposed within the organ environment and a vent valve disposed outside of the organ environment.

A portable housing for holding an organ or tissue for at least one of perfusion, storage, diagnosis, and transport of the organ or tissue includes a main chamber within which the organ or tissue and a liquid perfusate for the organ or tissue may be located, and it also includes a secondary chamber that is within the main chamber and that is for holding the liquid perfusate. A volume of the secondary chamber is less than a volume of the main chamber, and a top of the secondary chamber is below a top of the main chamber.

A thermo-protection-storage-cell (1) for the ensuring of a temperature range from a lower temperature exposure limit to an upper temperature exposure limit contains a thermo-cell body (2) and at least one filling chamber (3) which is arranged in the thermo-cell body (2). The at least one filling chamber (3) is filled with a first phase-change material (4) which changes its phase at the point of the lower temperature exposure limit. The at least one filling chamber (3) is filled with a second phase-change material (5) which changes its phase at the point of the upper temperature exposure limit. The thermo-protection-storage-cell (1) facilitates an efficient and safe ensuring of a temperature-sensitive good in a useful way, especially during its transport.

Provided herein are systems, methods, and kits for controlling and monitoring environmental conditions of a semen sample during transport. The technologies disclosed herein allow for at-home male fertility sample collection and subsequent transport to a laboratory to undergo fertility testing. One or more environmental conditions can be tracked during transport which provide the data used to determine whether a sample needs to be resubmitted or if the conditions during transport were such that a false test result is unlikely.

Disclosed herein is a transport device comprising a first section of an outer container comprising a shell on the inside having the shape of a spherical cap with an inner diameter and an opening, wherein the opening of the spherical cap faces upwards, and an inner container having an upper section, a lower section and an inner hollow volume defined thereby, wherein at least the lower section has a spherical shape on the outside, the outer diameter of which is smaller than the inner diameter of the spherical cap of the outer container. The inner container is suitable to be arranged in the spherical cap of the outer container in a freely pivotable fashion, and is capable of accommodating a payload.

A dry vapor cryogenic storage container includes an absorbent core made from a porous material that absorbs a liquid cryogen and releases the cryogen in vapor form as the absorbed liquid evaporates. Fluid channels are formed in the absorbent core to increase the available surface area through which the liquid cryogen can be absorbed. The core can absorb the cryogenic liquid much faster with inclusion of the fluid channels. The absorbent core can be made by cutting a cavity and drilling holes in a stack of calcium silicate panels. The cavity holds a contents container or an inner core. The inner core can be part of an extractor and made from porous material including fluid channels for absorbing liquid cryogen. Contents containers can be housed in the inner core.

The present invention discloses an afterload device for ex situ heart perfusion, which includes an afterload energy storage module, a pressure regulation module and two flow rate regulators that are connected through a conduit. The afterload energy storage module includes a rigid closed container and a flexible container. The perfusion fluid flows into the flexible container from one side thereof through the conduit, and the perfusion fluid flows out from the flexible container at another side thereof as the flexible container is subjected to the action of the medium pressure in the rigid hermetic container. The pressure regulation module includes two pressure regulation valves and a compressible-medium source, for regulating the pressure range within the rigid hermetic container to be always maintained between the set diastolic pressure and the set systolic pressure.

Systems and methods of the invention generally relate to prolonging viability of bodily tissue, especially an organ such as a lung, by adjusting pressure as needed to maintain a constant pressure within the organ even during external pressure fluctuations due, for example, to transportation of the organ in an airplane. Gas passing into and out of the organ may be conditioned to prolong tissue viability.

Systems and methods of the invention generally relate to prolonging viability of bodily tissue, especially lung tissue, through the use of an expandable accumulator to maintain a constant pressure within the lumen of the organ even during external pressure fluctuations due to, for example, flight. Systems and methods may include prolonging donor organ viability in storage through the use of an organ container that mimics the geometry and orientation of the organ in vivo.

A container unit (6) is provided for storing an organ or body tissue, wherein the container unit is configured as an insert for a storage apparatus and wherein the container unit comprises: a container body (602) defining a storage region; an inlet port (632) for connection to a fluid supply system to receive persufflation fluid; an outlet port (634) for connection to a said organ or body tissue stored in the container body; and a fluid processing device (604) comprising an internal passageway (636) connecting the inlet port to the outlet port, wherein the fluid processing device is configured to process, e.g. cool and humidify, persufflation fluid flowing through the internal passageway from the inlet port to the outlet port. The present disclosure also relates to a storage apparatus, a kit of parts, and a method of preparing an apparatus to store and preserve an organ or body tissue.