A mass spectrum resolution device for measuring laser ablation ion species with improved time of flight mass spectrometry includes a vacuum system unit, a plasma production unit, and a particle restraint selection and separation unit, wherein the particle restraint selection and separation unit comprises a particle limit selector and a plurality of ion pulse accelerated electrode plates; the particle limit selector comprises a restrainer lifting block, a restrainer and a restrainer selection baffle; a through hole is formed in the restrainer lifting block; a plurality of circular holes with different apertures are formed in the restrainer selection baffle, and the restrainer and the restrainer selection baffle are arranged in the restrainer lifting block and can move; and the ion pulse accelerated electrode plates are arranged in the advance direction of particles and are axially parallel to the restrainer lifting block.

An acceleration voltage generator is configured to cause a power MOSFET to turn on or off to switch a high direct-current voltage, so as to generate a high-voltage pulse for an ejection of ions from an ion ejector. A drive signal is used to cause the power MOSFET to turn on, and further includes a secondary drive signal to recharge a gate capacitance to cause the power MOSFET to stay in an on-state. In a drive signal generator, edge detection circuits generate an edge detection signal based on a start signal; selection circuits generate a primary drive signal by adjusting the edge detection signal in its signal width; and a secondary drive signal generator includes multiple circuit elements such as a semiconductor element, and generates the secondary drive signal.

Elongation of orthogonal accelerators is assisted by ion spatial transverse confinement within novel confinement means, formed by spatial alternation of electrostatic quadrupolar field (22). Contrary to prior art RF confinement means, the static means provide mass independent confinement and may be readily switched. Spatial confinement defines ion beam (29) position, prevents surfaces charging, assists forming wedge and bend fields, and allows axial fields in the region of pulsed ion extraction, this way improving the ion beam admission at higher energies and the spatial focusing of ion packets in multi-reflecting, multi-turn and singly reflecting TOF MS or electrostatic traps.

A mass spectrum resolution device for measuring laser ablation ion species with improved time of flight mass spectrometry includes a vacuum system unit, a plasma production unit, and a particle restraint selection and separation unit, wherein the particle restraint selection and separation unit comprises a particle limit selector and a plurality of ion pulse accelerated electrode plates; the particle limit selector comprises a restrainer lifting block, a restrainer and a restrainer selection baffle; a through hole is formed in the restrainer lifting block; a plurality of circular holes with different apertures are formed in the restrainer selection baffle, and the restrainer and the restrainer selection baffle are arranged in the restrainer lifting block and can move; and the ion pulse accelerated electrode plates are arranged in the advance direction of particles and are axially parallel to the restrainer lifting block.

A detector system for targeted analysis and/or sample collection by distance-of-flight mass spectrometry (tDOF-MS).

A time-of-flight (ToF) mass spectrometer, comprising: a pulsed ion injector for forming an ion beam that travels along an ion path; a detector for detecting ions in the ion beam that arrive at the detector at times according to their m/z values; an ion focusing arrangement located between the ion injector and the detector for focusing the ion beam in at least one direction orthogonal to the ion path; and a variable voltage supply for supplying the ion focusing arrangement with at least one variable voltage that is dependent on a charge state and/or an amount of ions of at least one species of ions in the ion beam. A corresponding method of mass spectrometry is provided. The charge state and/or an amount of ions may be acquired from a pre-scan, or predicted. Tuning of the spectrometer based on a charge state and/or an amount of ions of at least one species of ions in the ion beam may be performed on the fly.

A drive unit for driving an acceleration electrode of a mass spectrometer is disclosed. The drive unit includes a power converter comprising a switching element and pulsing circuitry that can form output pulses suitable for driving an acceleration electrode of a mass spectrometer. The drive unit also includes a controller that is configured to synchronise operation of the switching element with the pulsing circuitry.

A transfer electrode unit (240) is configured by coaxially arranging a plurality of loop electrodes (241A, 241B, 241C), and guides ions to an orthogonal acceleration region (242C) by allowing the ions to pass through an inner side of the plurality of electrodes (241A, 241B, 241C) each of which is applied with a voltage. A voltage having a higher absolute value than the voltage applied to the plurality of electrodes (241A, 241B, 241C) is applied to a flight tube (246), and the ions accelerated in the orthogonal acceleration region (242C) are introduced to a flight space formed in the flight tube (246). A shield portion (241F) is provided between the transfer electrode unit (240) and the flight tube (246), and suppresses that an electric field derived from the voltage applied to the flight tube (246) enters the transfer electrode unit (240).

Methods for confirming charged-particle generation in an instrument are provided. A method to confirm charged-particle generation in an instrument includes providing electrical connections to a charged-particle optics system of the instrument while the charged-particle optics system is in a chamber. The method includes coupling an electrical component having an impedance to charged-particle current generated in the chamber. Moreover, the method includes measuring an electrical response by the electrical component to the charged-particle current. Related instruments are also provided.

The driver condition detection system includes a driver monitor camera capturing a face of a driver of a vehicle and generating a facial image of the driver, and a driver condition detection part configured to detect a condition of the driver based on the facial image. If a part of face parts of the driver is hidden in the facial image, the driver condition detection part is configured to detect a condition of the driver based on face parts of the driver not hidden in the facial image. The face parts of the driver are a mouth, nose, right eye, and left eye of the driver.