A nicotine pouched product is disclosed, the nicotine pouched product having a pouch composition and a pouch membrane enclosing the pouch composition, the pouch composition including at least one water-insoluble fiber, water in an amount of at least 15% by weight of the composition, and nicotine, wherein the pouch membrane comprises further nicotine in an amount of at least 15% by weight of a total content of nicotine in the pouched product.

An oral pouched product is disclosed, the oral pouched product includes a saliva permeable pouch, a non-tobacco pouch composition, the pouch composition includes heat-treated fibers, nicotine in an amount of 0.1-5.0% by weight of the pouch compositions, water in an amount 15-65% by weight of the pouch composition, at least one sugar alcohol, and less than 0.5% preservative by weight of the pouch composition. Also, a method for manufacturing an oral pouched product is disclosed.

A method of manufacturing a concentrated tobacco extract for an aerosol-generating article is provided, including: providing a natural tobacco material; heating the material to a temperature and for a time such that volatile species including nicotine are released from the material, the heating includes heating the material in a flow of inert gas or in a flow of a combination of an inert gas with water or steam or heating the material under vacuum; collecting the released volatile species and forming a liquid, naturally derived tobacco extract including the collected species, a polyhydric alcohol, and at least about 40 percent by weight of water; and heating the liquid extract to evaporate at least some of the water and obtain concentrated tobacco extract, by heating to a temperature and for a time such that a water content in the naturally derived tobacco extract is reduced by at least about 60 percent.

A method of producing a liquid tobacco extract is provided, the method including the steps of: preparing a tobacco starting material including natural tobacco material such that during the step of preparing the tobacco starting material, the tobacco is not subjected to any treatment adapted to alter the pH of the tobacco; heating the tobacco starting material in a flow of inert gas at an extraction temperature of between 125 degrees Celsius and 160 degrees Celsius for between 90 minutes and 270 minutes; collecting volatile compounds released from the natural tobacco starting material during the heating step; and forming a liquid tobacco extract comprising the collected volatile compounds.

A liquid tobacco extract is provided, including: a non-aqueous solvent; at least 0.2 percent by weight of nicotine based on a weight of the liquid tobacco extract; and a ratio by weight of (β-ionone+β-damascenone) to (phenol) of greater than 0.25.

A method of producing a blended liquid tobacco extract, including: preparing a first tobacco starting material having a first reducing sugar content and a first nicotine content; preparing a second tobacco starting material having a second reducing sugar content and a second nicotine content, the first and the second starting materials being different from each other and have not been subjected to a prior extraction; heating the first tobacco starting material at a first extraction temperature; heating the second tobacco starting material at a second extraction temperature lower than the first extraction temperature; collecting volatile compounds released from the first and the second starting materials during heating; and combining the collected volatile compounds released from the first and the second starting materials and forming the blended liquid tobacco extract from the combined volatile compounds.

An oral pouched product is disclosed, the oral pouched product includes a saliva permeable pouch, a pouch composition, the pouch composition includes heat-treated fibers, nicotine, water in an amount of less than 65% by weight of the pouch composition, and at least one sugar alcohol. Also, a method for manufacturing an oral pouched product is disclosed.

The disclosure provides oral compositions and products including an active agent, a carrier/filler, and a buffer. Preferably, the composition can be configured such that, when in contact with a user's saliva, the composition is at a pH of about 6.5 to about 8. Buffers particularly may include amino acids, such as glycine, or salts thereof, as well as various phosphates.

The disclosure provides for oral compositions and products that can have a relatively low water content and/or a relatively low water activity. Such compositions and products can comprise at least one active ingredient, a filler/carrier component, and water in an amount of less than 10% by weight, based on the total weight of the composition. Further, the compositions and products can have a water activity of about 0.85 or less.

Two genes, A622 and NBB1, can be influenced to achieve a decrease of nicotinic alkaloid levels in plants. In particular, suppression of one or both of A622 and NBB1 may be used to decrease nicotine in tobacco plants.