A nicotine formulation for an aerosol-generating system is provided, the nicotine formulation including: one or more water-miscible polyhydric alcohols, the nicotine formulation having a water-miscible polyhydric alcohol content of greater than or equal to about 40 percent by weight, the nicotine formulation being solid at 25° C. or having a viscosity at 25° C. of greater than or equal to about 100 Pa.Math.s, the one or more water-miscible polyhydric alcohols including glycerine and propylene glycol, and a ratio of the weight percent glycerine content to the weight percent propylene glycol content of the nicotine formulation is greater than or equal to about 1.5. An aerosol-generating article and an aerosol-generating system are also provided.

An oral pouched product is disclosed, the oral pouched product includes a saliva permeable pouch, a pouch composition, the pouch composition includes heat-treated fibers, nicotine, water in an amount of less than 65% by weight of the pouch composition, and at least one sugar alcohol. Also, a method for manufacturing an oral pouched product is disclosed.

An oral pouched product is disclosed, the pouched product comprising a saliva permeable pouch and a pouch composition, the pouch composition comprising a powdered composition, water, and a liquid flavor composition, wherein the liquid flavor composition is added to the powdered composition after the water. A further oral pouched product and a method of manufacturing an oral pouched product is disclosed.

A nicotine pouch composition is disclosed, the pouch composition comprising free-base nicotine and having a water content of at least 15% by weight of said pouch composition. Furthermore, an oral nicotine pouch product comprising the pouch composition and a method for manufacturing the oral nicotine pouch product is disclosed.

An aerosol generating substrate comprising an aerosol generating material, wherein the aerosol generating material comprises an amorphous solid, the amorphous solid comprising 1-60 wt % of a gelling agent; 5-80 wt % of an aerosol generating agent; and 1-70 wt % of an active ingredient; wherein these weights are calculated on a dry weight basis; wherein bi-modal or multi-modal release of one or more active ingredients of the amorphous solid is observed in use.

An aerosol generating article for use in an aerosol generating assembly, the article comprising an aerosol generating substrate comprising an aerosol generating material, wherein the aerosol generating material comprises an amorphous solid, the amorphous solid comprising: 1-60 wt % of a gelling agent; 5-60 wt % of an aerosol generating agent; and 10-60 wt % of a tobacco extract; wherein these weights are calculated on a dry weight basis.

An aerosol generating assembly comprising an aerosol generating substrate and a heater which is configured to heat but not burn the aerosol generating material. The aerosol generating substrate comprises an aerosol generating material, the aerosol generating material comprising an amorphous solid. The amorphous solid comprises 1-60 wt % of a gelling agent, 0.1-50 wt % of an aerosol generating agent, and 0.1-80 wt % of a flavor, wherein these weights are calculated on a dry weight basis.

Two genes, A622 and NBB1, can be influenced to achieve a decrease of nicotinic alkaloid levels in plants. In particular, suppression of one or both of A622 and NBB1 may be used to decrease nicotine in tobacco plants.

An aerosolizable formulation having one or more aerosol-forming agents and a flavoring agent being an extract obtained from an alcoholic beverage, and wherein the extract contains less than about 5% v/v ethanol. A process for forming an aerosolizable formulation, forming an aerosol from the aerosolizable formulation, a contained aerosolizable formulation, an electronic aerosol provision system and the use of an extract obtained from an alcoholic beverage as a flavoring agent in an electronic aerosol provision system, wherein the extract contains less than about 5% v/v ethanol.

An extraction method of a flavor constituent comprises: a step A for heating a tobacco raw material which is subjected to an alkali treatment; and a step B for bringing a release component released in the gas phase in the step A into contact with a collection solvent at normal temperature until any time from when a first condition is satisfied to when a second condition is satisfied. The total amount of saccharides contained in the tobacco raw material is 9.0 wt % or less when a gross weight of the tobacco raw material in the dry state is 100 wt %. The first condition is determined based on variations in the pH of the collection solution. The second condition is determined based on the remaining amount of nicotine component.