The disclosure provides a composition including a filler, a lipid having a melting point of about 29° C. or above, water, and a flavoring agent or an active ingredient or both a flavoring agent and an active ingredient, which is optionally substantially free of isomalt and substantially free of tobacco material, excluding any nicotine component present, based on the total weight of the composition. The disclosure also provides compositions including a filler, a lipid having a melting point of about 29° C. or above, water in an amount of at least about 15% by weight, based on total weight of the composition, and a flavoring agent or an active ingredient or both a flavoring agent and an active ingredient.

The disclosure provides liquid aerosol precursor compositions adapted for use in an aerosol delivery device, comprising two or more organic acids. For example, one such composition includes: at least one aerosol former, nicotine, benzoic acid, lactic acid, and levulinic acid, wherein benzoic acid is present in a molar ratio of benzoic acid to nicotine of at least 0.15, wherein lactic acid is present in a molar ratio of lactic acid to nicotine of at least 0.2, and wherein levulinic acid is present in a molar ratio of levulinic acid to nicotine of at least 0.12. The disclosure further provides devices and kits incorporating such compositions.

The disclosure provides liquid aerosol precursor compositions adapted for use in an aerosol delivery device, comprising two or more organic acids. For example, one such composition includes: at least one aerosol former, nicotine, benzoic acid, lactic acid, and levulinic acid, wherein benzoic acid is present in a molar ratio of benzoic acid to nicotine of at least 0.15, wherein lactic acid is present in a molar ratio of lactic acid to nicotine of at least 0.2, and wherein levulinic acid is present in a molar ratio of levulinic acid to nicotine of at least 0.12. The disclosure further provides devices and kits incorporating such compositions.

A non-heating, non-combustion type flavor inhaler including a supply flow path unit including a first flow path leading aerosol toward a user side and a suction port, a liquid holding unit accommodating an aerosol base, a second flow path having one end communicating with the liquid holding unit and the other end which is located in the supply flow path unit and is opened toward the suction port side, and having a conductive portion, a liquid feeding system feeding the aerosol base, a power supply and a control unit applying a voltage to the conductive portion, to atomize the aerosol base and to eject the aerosol from an opening of the other end, and a static elimination unit neutralizing charge of the aerosol ejected from the opening.

A non-heating, non-combustion type flavor inhaler including a supply flow path unit including a first flow path leading aerosol toward a user side and a suction port, a liquid holding unit accommodating an aerosol base, a second flow path having one end communicating with the liquid holding unit and the other end which is located in the supply flow path unit and is opened toward the suction port side, and having a conductive portion, a liquid feeding system feeding the aerosol base, a power supply and a control unit applying a voltage to the conductive portion, to atomize the aerosol base and to eject the aerosol from an opening of the other end, and a static elimination unit neutralizing charge of the aerosol ejected from the opening.

A (Z)-solanone has the steric formula of:

##STR00001##

with the name of (S,Z)-5-isopropyl-8-methyl-6,8-diene-2-one or (R,Z)-5-isopropyl-8-methyl-6,8-diene-2-one. A process for the preparation of the (Z)-type solanone and the use thereof in flavoring of cigarette shred are further disclosed. The process includes the following steps: (1) reacting isopentanal and methyl vinyl ketone, under the action of a catalyst and a co-catalyst, to give (S)-2-isopropyl-5-carbonylhexanal or (R)-2-isopropyl-5-carbonylhexanal; (2) reacting the (S)-2-isopropyl-5-carbonylhexanal or the (R)-2-isopropyl-5-carbonylhexanal obtained in step (1) with (iodomethyl)triphenylphosphonium iodide, to give (S,Z)-7-iodo-5-isopropyl-6-ene-2-one or (R,Z)-7-iodo-5-isopropyl-6-ene-2-one; and (3) reacting the (S,Z)-7-iodo-5-isopropyl-6-ene-2-one or the (R,Z)-7-iodo-5-isopropyl-6-ene-2-one obtained in step (2) with pinacol isopropenylborate in the presence of a catalyst to give the (Z)-solanone.

A (Z)-solanone has the steric formula of:

##STR00001##

with the name of (S,Z)-5-isopropyl-8-methyl-6,8-diene-2-one or (R,Z)-5-isopropyl-8-methyl-6,8-diene-2-one. A process for the preparation of the (Z)-type solanone and the use thereof in flavoring of cigarette shred are further disclosed. The process includes the following steps: (1) reacting isopentanal and methyl vinyl ketone, under the action of a catalyst and a co-catalyst, to give (S)-2-isopropyl-5-carbonylhexanal or (R)-2-isopropyl-5-carbonylhexanal; (2) reacting the (S)-2-isopropyl-5-carbonylhexanal or the (R)-2-isopropyl-5-carbonylhexanal obtained in step (1) with (iodomethyl)triphenylphosphonium iodide, to give (S,Z)-7-iodo-5-isopropyl-6-ene-2-one or (R,Z)-7-iodo-5-isopropyl-6-ene-2-one; and (3) reacting the (S,Z)-7-iodo-5-isopropyl-6-ene-2-one or the (R,Z)-7-iodo-5-isopropyl-6-ene-2-one obtained in step (2) with pinacol isopropenylborate in the presence of a catalyst to give the (Z)-solanone.

There is provided a vaporizable formulation comprising (i) one or more solvents; and (ii) less than about 1 wt % of a cooling agent based on the weight of the vaporizable formulation; wherein the cooling agent volatilizes at a higher temperature than menthol at atmospheric pressure. There is also provided a vaporizable formulation comprising (i) one or more solvents; and (ii) less than about 12 wt % of a cooling agent based on the weight of the vaporizable formulation; wherein the cooling agent volatilizes at a higher temperature than menthol at atmospheric pressure and is a compound of formula (I) or a salt and/or solvate thereof as defined herein.

There is provided a vaporizable formulation comprising (i) one or more solvents; and (ii) less than about 1 wt % of a cooling agent based on the weight of the vaporizable formulation; wherein the cooling agent volatilizes at a higher temperature than menthol at atmospheric pressure. There is also provided a vaporizable formulation comprising (i) one or more solvents; and (ii) less than about 12 wt % of a cooling agent based on the weight of the vaporizable formulation; wherein the cooling agent volatilizes at a higher temperature than menthol at atmospheric pressure and is a compound of formula (I) or a salt and/or solvate thereof as defined herein.

An aerosol-generating film having a tobacco content of less than 1 percent by weight is provided, the aerosol-generating film including: a cellulose based film-forming agent; a non-cellulose based thickening agent; water; nicotine; and a polyhydric alcohol, a content of cellulose based film-forming agent being at least about 14 wt percent weight and less than or equal to about 26 wt percent, and a content of water being less than about 30 wt percent and a content of polyhydric alcohol is at least about 30 wt percent.