An image processing method, which is executed by a processor, comprises acquiring choroid information from an image of a fundus of an examined eye, and comparing the choroid information against a choroid normative database and determining whether or not there is an abnormality in the fundus.

An optical coherence tomographic device of polarization-sensitive type may include: an image capturing unit configured to capture a tomographic image of a subject eye, and a display unit configured to display the tomographic image captured by the image capturing unit. The tomographic image may include at least two images selected from a group consisting of: an image showing a tissue in the subject eye by scattering intensity, an image showing a melanin distribution in the subject eye, an image showing a fiber density in the subject eye, an image showing a fiber direction in the subject eye, and an image showing a blood flow in the subject eye. The display unit may be configured to display the at least two images at a same position and on a same cross section such that the at least two images are superimposed on each other.

An apparatus includes an obtaining unit configured to obtain, using an optical coherence tomography, an analysis map for a disk and an analysis map for a macular area, which are analysis results of three-dimensional data obtained by capturing an image of a region of a fundus of a subject's eye that includes the disk and the macular area, and a control unit configured to cause a display unit to display side by side a two-dimensional image of the region including the disk and the macular area, the analysis map for the optic disk, and the analysis map for the macular area.

A non perfusion area is detected from a fundus image. A fundus image is acquired, a first non perfusion area in a first region of the fundus is extracted from the fundus image, and a second non perfusion area in a second region of the fundus is extracted from the fundus image.

In an ophthalmological device, a memory stores a three dimensional data set acquired by applying OCT to a subject's eye. A fourth color coding unit assigns color information according to a depth position to the three dimensional data set. A fourth layer region identifying unit identifies layer regions by applying segmentation to the three dimensional data set, A fourth blood vessel region extracting unit extracts a blood vessel region from each of the layer regions identified. A fourth front image constructing unit constructs a front image based on each of the blood vessel regions extracted. A fourth image composing unit composes at least two of the front images constructed based on the color information, to construct a composite front image.

This invention relates to, in part, methods and compositions that are useful for the diagnosis, treatment, or prevention of a blinding eye disease, including in the discovery of drugs that are efficacious against these diseases. Diseases include, for example, age related macular degeneration and reticular pseudodrusen disease, and the methods described herein include, for example, the method named delayed near infrared analysis (DNIRA).

Examination of the structure and function of blood vessels is an important means of monitoring the health of a subject. Such examination can be important for disease diagnoses, monitoring specific physiologies over the short- or long-term, and scientific research. This disclosure describes technology and various embodiments of a system and method for imaging blood vessels and the intra-vessel blood flow, using at least laser speckle contrast imaging, with high speed so as to provide a rapid estimate of vessel-related or blood flow-related parameters.

An ophthalmic photography apparatus is provided with an irradiation optical system that irradiates a subject's eye with near-infrared light containing two or more wavelength components, a light receiving optical system that forms an image by concentrating reflected light derived from the near-infrared light reflected off a fundus or interior of the subject's eye, an imaging unit that outputs an image signal for each wavelength component by taking a fundus image or an intraocular image formed by the light receiving optical system, and an image generation unit that generates a fundus image or an intraocular image of the subject's eye by combining image signals outputted from the imaging unit.

Formulations and methods of treatment are disclosed for prevention and/or treatment of visual loss from age-related macular degeneration. The disclosed formulations include botulinum neurotoxin. The disclosed formulations may be applied to an intraocular or extraocular region of a patient. If applied to an extra ocular region of a patient, the botulinum-based pharmaceutical formulation may then be transported to the intra-ocular region of the patient, allowing the active ingredient(s) to penetrate into the choroid, neuro-retina, and/or retinal pigment epithelium without direct injection into the eye, eliminating risk of retinal detachment, retinal break, retinal hemorrhage, and blindness. The methods described herein allow for increased blood flow to the choroid, which improves removal of metabolites and intra retinal fluid and also serves to arrest, reverse and/or delay early and later stages of age-related macular degeneration.

Methods for the prevention and treatment of ocular disorders, in particular glaucoma, through blocking the toxic effects of β-amyloid (Aβ) derivatives, and pharmaceutical compositions for effecting such prevention and treatment thereof.