Optical geometry calibration devices, systems, and related methods for x-ray imaging are disclosed. An optical-based geometry calibration device is configured to interface with a two-dimensional (2D) imaging device to perform three-dimensional (3D) imaging. The optical-based geometry calibration device includes one or more optical cameras fixed to either an x-ray source or an x-ray detector, one or more markers fixed to the x-ray detector or the x-ray source, with each of the one or more optical cameras being configured to capture at least one photographic image of one or more corresponding optical markers when each x-ray image of the object is captured, and an image processing system configured to compute positions of the x-ray source relative to the x-ray detector for each 2D projection image based on the at least one photographic image of the one or more markers

There is provided a method for at least partly determining the orientation of an edge-on x-ray detector with respect to the direction of x-rays from an x-ray source. The method includes obtaining (S1) information from measurements, performed by the x-ray detector, representing the intensity of the x-rays at a minimum of two different relative positions of a phantom in relation to the x-ray detector and the x-ray source, the phantom being situated between the x-ray source and the x-ray detector and designed to embed directional information in the x-ray field when exposed to x-rays. The method also includes determining (S2) at least one parameter associated with the orientation of the x-ray detector with respect to the direction of x-rays based on the obtained information from measurements and a geometrical model of the spatial configuration of the x-ray detector, x-ray source and phantom.

Provided is a method of generating a virtual x-ray image, the method including: obtaining a 3-dimensional (3D) image of a patient; determining a projection direction of the 3D image in consideration of a position relationship between an x-ray source of an x-ray device and the patient; and generating a virtual x-ray image by projecting the 3D image on a 2D plane in the determined projection direction.

A method for repositioning a mobile imaging system includes: a) capturing an image recording of at least one optical marker as a reference variable which is disposed close to an examination and/or treatment area of an object, b) capturing the image recording direction as a further reference variable, c) wherein the capturing mobile imaging system is in a predefined position and/or alignment suitable for image recording, d) detecting a changed and/or non-capturable position of the at least one optical marker and/or a changed and/or non-capturable image recording direction, and e) repositioning the mobile imaging system using a comparison of the reference variables from a) and b) with the respectively corresponding reference variables from d). An image capturing unit and an optical marker are also provided.

Disclosed is a calibration phantom for an x-ray imaging system having an x-ray source and an x-ray detector. The calibration phantom includes a combination of geometric objects of at least three different types and/or compositions including: a first object located in the middle, including a first material; a plurality of second objects arranged around the periphery of the first object, at least a subset of the second objects including a second material different than the first material, wherein the first object is relatively larger than the second objects; a plurality of third objects arranged around the periphery of the first object and/or around the periphery of at least a subset of the second objects, at least a subset of the third objects including a third material different than the first material and the second material, wherein the third objects are relatively smaller than the second objects.

A method for determining the position and/or orientation of at least one sensor system relative to the base structure of a scanning system during scanning of an object, the method includes obtaining one or more tracking images using one or more cameras, where the cameras are in a fixed position with respect to the sensor system; and determining from the one or more tracking images the position and/or orientation of the sensor system relative to the base structure at a given time.

Disclosed are a quantum dot population including a plurality of cadmium free quantum dots, a quantum dot polymer composite including the same, and a display device including the same. The plurality of cadmium free quantum dots includes: a semiconductor nanocrystal core comprising indium and phosphorous, a first semiconductor nanocrystal shell disposed on the semiconductor nanocrystal core and comprising zinc and selenium, and a second semiconductor nanocrystal shell disposed on the first semiconductor nanocrystal shell and comprising zinc and sulfur, wherein an average particle size of the plurality of cadmium free quantum dots is greater than or equal to about 5.5 nm, a standard deviation of particle sizes of the plurality of cadmium free quantum dots is less than or equal to about 20% of the average particle size, and an average solidity of the plurality of cadmium free quantum dots is greater than or equal to about 0.85.

Various embodiments of an X-ray imaging system employ a C-arm (60) and an X-ray overlay controller (410). In a planning overlay display mode, the controller (410) processes a planning X-ray image (420) and a reference planning X-ray image (421), both illustrative of the planning X-ray calibration device (400) and further processes a base X-ray image (424, 425) (422) illustrative of a base X-ray calibration device to control a display of a planned tool trajectory overlay (412) and a tracked tool position overlay (413) onto the planning X-ray image (420). In a guiding overlay display mode, the controller (410) processes a pair of interventional X-ray images (424, 425) and a guiding X-ray image (426), all illustrative of a guiding X-ray calibration device (402), to control a display of a guidance tool trajectory overlay (414) and a racked tool position overlay (415) onto the guiding X-ray image (426).

A valence of a target element of a sample and crystallinity of a sample can be detected with a small device. The analysis device 100 includes: a placement holder 110 for placing a sample S; an X-ray source 11 for irradiating the sample S with X-rays; a first detector 141 for detecting characteristic X-rays generated from the sample S by the irradiation of the X-rays; a second detector 142 for detecting X-rays diffracted by the sample; and a signal processing device 20. The signal processing device 20 detects the valence of the target element of the sample based on the characteristic X-rays detected by the first detector 141, and detects the crystallographic data of the sample based on the X-rays detected by the second detector 142.

A method of performing a radiological biopsy and associated system includes scanning a living human subject with a CT scanner to locate coordinates of an area of potential pathology and then using the coordinates to direct synchrotron radiation to a location at, or proximat the coordinates to obtain a high-resolution image of the area of potential pathology. The CT scan is accomplished with a CT scanner such as a C-Arm, vertical or horizontal CT scanner. A synchrotron radiation source emits synchrotron radiation through the subject and is processed by a processing system. The method and system allow for concurrent or sequential scanning of the subject by the CT scanner and synchrotron radiation scanner. The resulting images provide histological resolution of areas of potential pathology.