A system for patient cardiac imaging and tissue modeling. The system includes a patient imaging device that can acquire patient cardiac imaging data. A processor is configured to receive the cardiac imaging data. A user interface and display allow a user to interact with the cardiac imaging data. The processor includes fat identification software conducting operations to interact with a trained learning network to identify fat tissue in the cardiac imaging data and to map fat tissue onto a three-dimensional model of the heart. A preferred system uses an ultrasound imaging device as the patient imaging device. Another preferred system uses an MRI or CT image device as the patient imaging device.

Prostate biopsy systems are provided that include a 3D ultrasound probe support configured to receive an ultrasound probe for transperineal imaging. One or more template grids can have a plurality of apertures extending therethrough to receive and guide a biopsy needle along a trajectory associated with respective apertures when the template grid is fixed to the support and the biopsy system is positioned in the perineal area of a patient. Patient-specific template grids can also be developed and produced. This system enables fully transperineal prostate biopsy (i.e. both imaging and needle placement are perineal) and eliminates the need for an external racking device for image fusion as well as needle tracking. In addition, it reduces the infection risk associated to transrectal approach.

Systems and methods are disclosed for identifying features of a blood vessel using extravascular and intravascular images in order to estimate a virtual flow reserve (VFR) of the imaged blood vessel. Aspects of the disclosure include using extravascular images to estimate the size of the blood vessel in regions that have not been intravascularly imaged. The VFR estimation may be based on a resistance model that incorporates both the intravascular image data and the estimated blood vessel size. In other aspects, multiangled extravascular images are captured and analyzed in order to identify the size and orientation of branch vessels.

Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart, and create a three-dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model.

An ultrasound imaging probe (204) includes a transducer array (210). The transducer array includes one or more transducer elements (212). The ultrasound imaging probe further includes an illumination component (218) and an optical imaging component (220). The ultrasound imaging probe further includes an elongated housing (302) with a long axis (304). The elongated housing includes a proximal end region (306) affixed to a handle (308) and a distal end region (310) with a tip region (312). The elongated housing houses the transducer array, the illumination component, and the optical imaging component in the distal end region.

A system and method for prostate cancer treatment under local anesthesia includes creating a superficial skin and subcutaneous block in a perineal area of a patient by administering a first anesthetizing agent; creating a deep nerve block under ultrasound guidance by administering a second anesthetizing agent, the second anesthetizing agent infiltrating cavernosal nerve bundle tissue and periprostatic space; and ablating prostate tissue. The office-based method, statistical models and computer generated treatment plans identify and ablate prostate tissue containing cancer through or via the perineum while preserving prostate function, and critical anatomical structures. Multiple technologies are integrated and processed to deliver a safe treatment procedure, under local anesthesia by integrating the information of magnetic resonance imaging and planning the ablative treatment using algorithms that ensure maximal precision in both killing cancerous tissue and preserving healthy tissue along with its corresponding function.

In an ultrasound diagnostic apparatus and an operation method of the ultrasound diagnostic apparatus of the invention, a control circuit performs polarization processing on a plurality of ultrasound transducers in a non-diagnosis period, during which transmission of ultrasound waves and reception of reflected waves for performing ultrasound diagnosis are not performed, in a case where the cumulative driving time of the plurality of ultrasound transducers for performing the ultrasound diagnosis becomes equal to or longer than a specified time. A transmission circuit generates a first transmission signal having a driving voltage for performing ultrasound diagnosis using a pulse generation circuit in the case of performing the ultrasound diagnosis, and generates a second transmission signal having a polarization voltage for performing polarization processing using the same pulse generation circuit as in the case of generating the first transmission signal in the case of performing the polarization processing.

Multi-modal medical image registration and associated devices, systems, and methods are provided. For example, a method of medical imaging can include: receiving a first image of a patients anatomy in a first imaging modality; receiving a second image of the patients anatomy in a second, different imaging modality; determining a first pose of the first image relative to a reference coordinate system of the patients anatomy; determining a second pose of the second image relative to the reference coordinate system; determining co-registration data between the first image and the second image based on the first pose and the second pose; and outputting, to a display, the first image co-registered with the second image based on the co-registration data.

Systems and methods for mapping a region of interest within breast tissue utilize multiple layers of information to produce a unique digital fingerprint of breast tissue. X-ray and ultrasound imaging is combined with elastography and Doppler to create an architectural map of a breast including coordinates to mark one or more regions of interest. The architectural map can be utilized during future imaging procedures and surgeries to automatically and virtually indicate the location of previously biopsied lesions. The architectural map can be displayed on a user interface of a computing device to guide a user to the region of interest during imaging.

A device is for estimating a blood pressure of a user by a combination of an acoustic mode employing acoustic emitters and acoustic detectors and an optical mode using light sources and photodetectors forming source—detector pairs. The device includes an acoustic selection unit to determine the pertinent acoustic emitter—acoustic detector pair as well as an optical selection unit to determine the pertinent light source—photodetector pairs.