A system for generating data relating to a tissue core comprises a core needle biopsy module configured to obtain a tissue core from a locus within the body, and a tissue disintegration module operably connected to the core needle biopsy module and configured to receive a tissue core from the core needle biopsy module and convert at least a portion of the tissue core into gaseous tissue molecules. The system also comprises first vacuum pump means configured to convey a tissue core from the needle biopsy module to the tissue disintegration module, and second vacuum pump means configured to convey gaseous tissue molecules from the tissue disintegration module to an analyser module.

A biopsy system includes a biopsy device, a control module, and a tissue transport tube. The biopsy device includes a probe, a needle, a cutter, and a transport valve. The needle extends distally from the probe. The cutter is movable relative to the needle and defines a cutter lumen. The holster is configured to couple to the probe. The transport valve is in communication with the cutter lumen. The control module is in communication with the biopsy device and includes a sample management assembly configured to receive one or more tissue samples severed by the cutter. The transport tube extends between the sample management assembly and the biopsy device. The transport tube is in communication with the transport valve such that the transport tube is configured to receive the one or more tissue samples severed by the cutter.

A biopsy needle arrangement comprises a needle sheath and a needle. The biopsy needle arrangement is configured to be operatively connected to an actuator device configured to push the needle and the sheath distally in a sliding direction x. The biopsy needle arrangement further comprises a needle connector configured to attach the needle to the actuator device and a sheath connector configured to attach the needle sheath to the actuator device. The needle connector is configured to disengage the needle from the actuator device when the needle is subjected to a force in the sliding direction, which exceeds a threshold force. Also or alternatively, the sheath connector is configured to disengage the needle sheath from the actuator device when the needle sheath is subjected to a force in a direction opposite the sliding direction, which exceeds a threshold force.

A biopsy device includes a cylindrical hollow stylet having a proximal end, a distal end, and a uniform wall thickness. The proximal end and the distal end are disposed on the longitudinal axis. A longitudinal recess forms a sample chamber and is positioned adjacent the distal end of the cylindrical hollow stylet. A longitudinal insert has a longitudinal length, a distal terminal end, and an elongate channel. The longitudinal insert is positioned within the cylindrical hollow stylet with the distal terminal end proximal to the longitudinal recess. The longitudinal insert is immovably connected to the cylindrical hollow stylet. The elongate channel is configured to maintain a fluid passageway through the cylindrical hollow stylet from the proximal end to the longitudinal recess.

Medical devices and methods for removing a predetermined portion of soft tissue from a target tissue layer, thereby creating a channel between two side walls of the target tissue layer, are described. The medical device is a cutting tool comprising: an elongated round body extending along a longitudinal axis and having a uniform outer cross-section at a proximal side thereof; a cutting portion at a distal side of the elongated body, comprising at a distal end thereof a cutting edge of a first cross-section being smaller than said outer cross-section, and a distally and continuously decreasing outer cross-section; and a chamber extending along the longitudinal axis inside the cutting tool from said cutting portion, the chamber having dimensions enabling storing of the removed soft tissue portion inside the chamber thereby providing a validation to the channel creation.

A device including a probe unit and a driver unit for tissue extraction and sample collection is disclosed. The probe unit includes an injection unit, a driving mechanism, a filtering mechanism and a tissue sample container. The injection unit includes a needle actuated by a prime-mover and the driving mechanism, which drives the needle into the subject for extraction of tissue sample. The tissue extraction is performed by a rotational motion of the needle and pressure. The pressure is provided by a pressure subsystem in the lumen of the needle and the tissue is collected in the tissue sample container. The amount of pressure applied is controlled by a control subsystem based on the organ specific requirement.

A tissue cutting device that is especially suited for neurosurgical applications is disclosed and described, as well as alternative systems for tissue preservation and transport. The cutting device includes an outer cannula in which a reciprocating inner cannula is disposed. A tissue collector is also provided and is in fluid communication with the lumen of the inner cannula. A temperature control sleeve may be disposed around the tissue collector to control the temperature of the tissue samples. A preservation system may be supplied that is configured to deliver fluids to tissue samples in the tissue collector. A fluid supply sleeve may be disposed about the outer cannula and is selectively positionable along the length of the outer cannula.

A full core biopsy device includes a needle assembly having stylet, spoon, and at least one coring cannula. A window is located in at least one of the spoon and coring cannula. An excising finger is configured to prolapse through the window into a lumen of the inner spoon or cannula to sever a tissue sample upon translation or axial advancement of the excising finger.

Devices, systems and methods useable for useable for monitoring a physiological variable in a target tissue or body fluid located within the thorax of a subject by optical spectroscopy.

A biopsy needle for collecting a tissue specimen includes an outer cannula and an inner tube received within the outer cannula and configured to receive a stylet. The outer cannula is fixedly coupled to a needle holder that is coupled to and moves with a movable base that is axially movable within the handle housing. An inner driven structure (curvilinear part) is configured to selectively engage the movable base and travel therewith in a first stage of operation and in a second stage of operation in which the inner driven structure is disengaged from the movable base, the inner driven structure is driven along the movable base which is held in a stationary position. The coupling between the inner driven structure and the inner tube is such that the axial driving of the inner driven structure imparts rotation to the inner tube relative to the outer cannula.