A system is provided that furnishes expert procedural guidance based upon patient-specific data gained from surgical instruments incorporating sensors on the instrument's working surface, one or more reference sensors placed about the patient, sensors implanted before, during or after the procedure, the patient's personal medical history, and patient status monitoring equipment. Embodiments include a system having a surgical instrument with a sensor for generating a signal indicative of a property of a subject tissue of the patient, which signal is converted into a current dataset and stored. A processor compares the current dataset with other previously stored datasets, and uses the comparison to assess a physical condition of the subject tissue and/or to guide a procedure being performed on the tissue.

Embodiments include a clamp for a medical procedure, the clamp having a first clamp member having a first end and a second end, a second clamp member having a first end and a second end, a hinge, the hinge coupling the first ends of the first and second clamp members, a biasing member, the biasing member coupling the second ends of the first and second clamp members, the biasing member being configured to apply a first clamping force in a first stage, and a second clamping force in a second stage, where the second clamping force is greater than the first clamping force.

A cordless, hand-held dermatologic hair-regrowth-inhibiting apparatus may include: a self-contained housing configured for gripping by a person's hand for cordless manipulation in a hair-regrowth-inhibiting procedure; a light source comprising one or more diode laser bars within the housing; a direct drive electrical circuit within the housing comprising one or more batteries for energizing the light source to produce output light pulses, wherein the electrical circuit does not include any storage capacitors that energize the light source by capacitor discharge; and a light path within the housing including an aperture through which the output light pulses are propagated out of the housing having properties sufficient for at least temporary hair-regrowth inhibition.

A dermatologic hair-regrowth-inhibiting apparatus is disclosed which is cordless and sufficiently compact as to be hand-held. A self-contained housing is configured for gripping by a person's hand for cordless manipulation in a hair-regrowth-inhibiting procedure. A light source and electrical circuit are contained within the housing. The circuit includes one or more batteries for energizing the light source to produce output light pulses. A light path within the housing includes an aperture through which eye-safe light pulses are propagated out of the housing having properties sufficient for at least temporary hair-regrowth inhibition. A diffuser is disposed along the light path to reduce the integrated radiance to an eye-safe level.

The measurement system 110 comprises a light source 120 configured and arranged for emitting a light beam via a polarization modulator 130 to a target position inside the skin 160, wherein the polarization modulator 130 is configured and arranged to simultaneously provide, in use, a first and a second region in a cross-section of the light beam in the target position, the first and the second region being distinct and having a corresponding first and second direction of polarization, the first and the second polarization direction being different from each other, and the measurement system also comprises a detection unit 150 to simultaneously detect a first and a second intensity of reflected light 145, the first intensity corresponding to light reflected from the first region of the light beam in the target position 160, and the second intensity corresponding to light reflected from the second region of the light beam in the target position 160, and the measurement system further comprises a processor being coupled to the detection unit 150 for determining a difference between the first and the second intensity.

Various examples are directed to systems and methods for operating and controlling a modular surgical instrument comprising an operating mode. A controller may receive electrical signal associated with an activation of at least one user-actuated input device electrically coupled to the controller and override the operating mode of the surgical instrument upon receiving the electrical signal.

Systems are provided for delivering a calibrated ultraviolet radiation pulse at a treatment plane during a laser-ablation treatment of a patient's eye. Exemplary systems include an ultraviolet radiation source, and a fluorescent plate positioned to receive an initial ultraviolet radiation pulse produced by the ultraviolet radiation source. The fluorescent plate generates a visible light pulse in response to the initial ultraviolet radiation pulse. Exemplary systems further include a photon detector positioned to receive the visible light pulse for generating an electrical signal in response to the visible light pulse, and a processing module configured to determine an energy of the initial ultraviolet radiation pulse based on an amplitude and a decay time of the electrical signal, determine an energy calibration signal based on the determined energy of the initial ultraviolet radiation pulse, and provide the energy calibration signal to the ultraviolet radiation source for producing the calibrated ultraviolet radiation pulse.

A system for working biological tissue, the system comprising: a tool comprising a laser operable to perform at least one action of work; positioning means for positioning the tool relative to the biological tissue to perform the at least one action of work; a controller; storage storing electronic program instructions for controlling the controller; and an input means; wherein the controller is operable, under control of the electronic program instructions, to: receive input via the input means; process the input and, on the basis of the processing, control the positioning means and the tool to work the biological tissue.

A system and method for compensation of angular distortions in a system utilizing light emitters and light sensors disposed on non-parallel jaws may include determining a first point at a first side of a region of interest and a second point at a second side of the region of interest, determining a linear curve including the first and second points, and utilizing the linear curve to remove the angular distortion from the region of interest between the first and second points, A system and method for compensation of angular distortions may alternatively include modeling a non-pulsatile illumination pattern according to the intensities of individual emitters, comparing the pattern according to the model against a non-pulsatile illumination pattern detected using the light sensors, and varying the intensities of the individual emitters based on the comparison until angular distortion has been removed.

A method for tissue assessment includes ablating tissue at a site within a body of a living subject using an invasive probe applied to the site. At a first stage in ablation of the tissue, first measurements are made of scattered light intensities from the site at a plurality of different wavelengths. At a second stage in the ablation of the tissue, subsequent to the first stage, second measurements are made of the scattered light intensities from the site at the plurality of different wavelengths. Progress of the ablation is assessed by computing different, respective measures of change in the scattered light intensities at the different wavelengths occurring between the first and second measurements, and comparing the respective measures.