A medical probe includes an elongate body for insertion into an organ of a patient, and an electrode that is attached to the elongate body. Multiple thermocouples are disposed at respective different locations of the electrode and electrically coupled to the electrode, and are configured to sense respective temperatures at the locations.

An ultrasonic surgical instrument including a blade that treats tissue and a fluid control system to cool the blade by pumping cooling fluid through the blade. The blade defines a blade lumen in fluid contact with an inflow and return conduit of the fluid control system. The fluid control system may further include a fluid reservoir holding the cooling fluid and a pump. The pump is configured to deliver the fluid from the fluid reservoir, through the inflow conduit and the blade lumen, and into return conduit.

Apparatus, consisting of a power supply having a first electrical connection to a relatively high voltage source and connectable to ablation circuitry in a catheter via a second electrical connection. There are rechargeable first and second subsidiary power sources in the power supply. The apparatus also has a control unit, and a first switch alternately connecting the ablation circuitry to the first and second subsidiary power sources responsively to control signals from the control unit. The apparatus also has a second switch alternately connecting one of the first and second subsidiary power sources to the high voltage source for recharging thereof responsively to the control signals while the one of the first and second subsidiary power sources is disconnected from the ablation circuitry and another of the first and second subsidiary power sources is connected to the ablation circuitry by the first switch.

An embodiment includes a system comprising: a catheter; an optic fiber having a long axis and a short axis that is orthogonal to the long axis; first and second radiopaque elements coupled to the optic fiber; a first wire coupled to the optic fiber and extending from the first radiopaque element to the second radiopaque element; a fluid; wherein (a)(i) the first wire wraps at least partially around an exterior surface of the optic fiber; (a)(ii) an outer diameter of the first wire and an outer diameter of the optic fiber are collectively less than an inner diameter of the catheter, and (a)(iii) the first wire is configured to center the optic fiber within the catheter within a plane orthogonal to the long axis.

A thrombectomy system includes an aspiration catheter configured for advancement through vasculature of a subject to facilitate clot removal from the vasculature of the subject. The thrombectomy system includes a fluid jet proximate to a distal end of the aspiration catheter. The thrombectomy system includes a flow direction sensor positioned on the aspiration catheter proximate to the fluid jet. The flow direction sensor is configured to detect a flow direction of fluid at a distal region of the aspiration catheter during operation of a clot removal state of the thrombectomy system. The flow direction of the fluid at the distal region of the aspiration catheter indicates a clog state of the aspiration catheter.

A surgical instrument includes a transducer configured to produce vibrations at a predetermined frequency. An ultrasonic end effector extends along a longitudinal axis and is coupled to the transducer. The ultrasonic end effector comprises an ultrasonic blade and a clamping mechanism. A controller receives a feedback signal from the ultrasonic end effector and the feedback signal is measured by the controller. A lumen is adapted to couple to a pump. The controller is configured to control fluid flow through the lumen based on the feedback signal, and the lumen is located within the ultrasonic end effector.

Disclosed herein are the systems, devices and methods for treating cancer and metastasis using low energy immune priming. The low energy immune priming includes administering immunopriming energy. The low energy immune priming can be combined with an adjunct therapy.

A cryosurgery system, comprising two or more cryoprobes is provided. Each cryoprobe includes a probe shaft having a distal section insertable in a patient and a proximal coupler. A connector interface with connection ports permits connections to a corresponding cryoprobe. Each connection port can have an isolating sleeve between the proximal coupler and the connection port when the proximal coupler of the respective cryoprobe is inserted in the connection port. The isolating sleeve can include an electrically insulating material so as to electrically isolate each cryoprobe connected to its corresponding connection port from other cryoprobes connected to their corresponding connection ports. An electrical measurement system can be connected to each connection port to detect electrical signals associated with the probe shaft. A control system can detect, based on the electrical signals detected by the electrical measurement system whether the probe shaft is electrically connected to the electrical heater.

Aspects of the present disclosure are directed to, for example, a method for determining a temperature distribution across an ablation catheter tip. The method including contacting tissue with a distal tip of an ablation catheter, receiving temperature data from a plurality of thermocouples distributed about the distal tip of the ablation catheter, and based on the received temperature data, determine a temperature distribution across the distal tip of the ablation catheter. Also disclosed is a method of controlling the temperature of an ablation catheter tip while creating a desired lesion using various energy sources and energy delivery methodologies.

Disclosed embodiments relate to devices, systems, and methods of shaping, shrinking, opening, dilating, stiffening, or otherwise modifying a Eustachian tube and its surrounding tissue in order to improve the Eustachian tube's function. For example, patients with blocked, closed, or hypertrophic Eustachian tubes may be able to achieve improved function including easier equalization of pressure between the inner ear and environment.