A systemic human repair and enhancement system that provides stem cell therapy utilizing an apparatus and methods for administering a treatment schedule of non-invasive and drug-free narrow and specific 0.6180 Hz frequency continuous sine wave therapy to the patient's cells. The frequency therapy may be in-vivo and in-vitro applications. The frequency therapy stimulates systemic stem cell production, particularly at a tissue sites having loss of function due to a condition, aging, damage, and or disease. The frequency therapy system encompasses a narrow and specific ultra-low continuous sine wave frequency stimulation therapy that produces one or more of the enhanced cell production, release, viability, proliferation, migration and or engraftment of the human patient's own genetically compatible stem cells, and the therapy enhances the stem cell's secretions thereby safely enhancing the secretion's therapeutic effects during stem cell therapy and simultaneously systemically enhancing the patient's pre-existing cells and tissues.

A generator, ultrasonic device, and method for controlling a temperature of an ultrasonic blade are disclosed. A control circuit coupled to a memory determines an actual resonant frequency of an ultrasonic electromechanical system comprising an ultrasonic transducer coupled to an ultrasonic blade by an ultrasonic waveguide. The actual resonant frequency is correlated to an actual temperature of the ultrasonic blade. The control circuit retrieves from the memory a reference resonant frequency of the ultrasonic electromechanical system. The reference resonant frequency is correlated to a reference temperature of the ultrasonic blade. The control circuit then infers the temperature of the ultrasonic blade based on the difference between the actual resonant frequency and the reference resonant frequency. The control circuit controls the temperature of the ultrasonic blade based on the inferred temperature

Various embodiments are described herein for a device for using acoustic or mechanical energy to perform an action at a target site of an object. The device comprises a conduit having an aperture disposed at the target site, a displacement signal source for generating a mechanical displacement signal, a coupling assembly having for coupling the displacement signal source to the conduit, a pressure controller coupled to the proximal end of the conduit to vary an amount of pressure in the conduit when obtaining a first entity from or delivering a second entity to the target site, and a control unit for controlling the displacement signal source to generate the mechanical displacement signal based on a desired acoustic or mechanical wave mode.

A method of controlling the temperature of an ultrasonic blade between two temperature set points includes applying a first power level to an ultrasonic transducer to set an ultrasonic blade temperature to a first target temperature T1, monitoring a phase angle φ between voltage V.sub.g(t) and current I.sub.g(t) signals applied to the transducer, inferring the temperature of the blade based on the phase angle φ, determining that a transection process is complete, and applying a second power level to the transducer to set the blade temperature to a second target temperature T2. The transducer may be coupled to the blade via an ultrasonic waveguide. The first target temperature may be optimized for vessel sealing and the second target temperature may be optimized for clamp arm pad life. The control circuit may determine that transection is complete by determining that the ultrasonic blade contacts the clamp arm pad.

An ultrasonic device may include an electromechanical ultrasonic system having a resonant frequency, the system including a transducer coupled to an ultrasonic blade. A method of driving the blade may include determining a tissue type contacting the blade, setting current delivered to the transducer to achieve a desired blade temperature, and setting a desired period during which the desired temperature is applied to the tissue. The tissue type may be determined by measuring an impedance of the transducer, comparing an impedance measurement data point to a reference data point, and classifying the impedance measurement data point based on a result of the comparison. Alternatively, the tissue type may be determined by applying a drive signal to the transducer, sweeping the frequency of the drive signal from below to above a resonance of the ultrasonic system, measuring and recording impedance/admittance variables, and comparing the measured variables to reference variables.

A method of determining an initial temperature of an ultrasonic blade may include measuring a resonant frequency of an ultrasonic blade prior to activating an ultrasonic transducer, in which the ultrasonic transducer is coupled to the blade via an ultrasonic waveguide, comparing the measured resonant frequency to a baseline resonant frequency, determining an initial temperature of the ultrasonic blade based on a difference between the measured resonant frequency and the baseline resonant frequency, and applying a power level to the blade based on the initial temperature of the blade. The method may further include applying a high power level to the transducer when the initial temperature of the ultrasonic blade is low or applying a low power level to the transducer when the initial temperature of the blade is high. The baseline resonant frequency may be stored in a memory look up table.

Systems and associated methods for ultrasonically-assisted placement of orthopedic implants are described herein. An example system includes an ultrasonic generator, a transducer, and a probe, surgical instrument, and/or an implant. Ultrasonic energy can be delivered to a region of a bone using the system to remove a portion of the bone.

A method of determining instability of an ultrasonic blade includes monitoring a phase angle φ between voltage Vg(t) and current Ig(t) signals applied to an ultrasonic transducer, coupled to an ultrasonic blade via an ultrasonic waveguide, inferring the blade temperature based on the phase angle φ, comparing the inferred temperature to an ultrasonic blade instability trigger point threshold, and adjusting a power level applied to the ultrasonic transducer to modulate the temperature of the blade. The method may also include determining a frequency/temperature relationship of an ultrasonic blade that exhibits a displacement or modal instability and compensating for a thermal induced instability of the ultrasonic blade. The method may be implemented in an ultrasonic surgical instrument or by a control circuit in a power generator for the ultrasonic surgical instrument.

A radio frequency (RF) instrument may include a method of classifying a tissue in live time. The method may include activating the instrument for a first period of time T1 when the RF instrument contacts the tissue, plotting at least three electrical parameters associated with the tissue to classify the tissue into distinct groups, and applying a classification algorithm to classify the tissue into a distinct group in live time. The parameters may include an initial impedance of the tissue, a minimum impedance of the tissue, and an amount of time that the impedance slope is ˜0. The instrument may collect the parameters during a predetermined amount of time, such as within the first 0.75 seconds of the activation of the device. The classification algorithm may include a support vector machine algorithm that may use a linear, polynomial, or radial basis set.

A piezoelectric device comprising: (a) a handpiece for holding by a user; (b) a cutting insert for said handpiece; (c) an ultrasound transducer disposed within the handpiece, the ultrasound transducer capable of providing first and second ultrasound frequency vibrations to the cutting insert in response to an electrical signal; and (d) a switch allowing the user to control the electrical signal and thereby provide either said first or second ultrasound frequency vibrations to the cutting insert.
The device is useful in a method of placing an implant into an implant site comprising cutting overlying gingival tissue at a first ultrasound frequency capable of cutting soft tissue, then switching to a second ultrasound frequency capable of cutting the underlying jawbone.