Systems and methods for improving vision of a subject implanted with an intraocular lens (IOL). In some embodiments, a method of treating an ocular disease of a subject having an implanted intraocular lens (IOL) includes determining visual needs of a subject that are associated with an ocular disease of the subject determining a pattern of a plurality of pulses of radiation to apply, by refractive index writing, and applying the plurality of pulses of radiation to the one or more selected areas of the IOL.

A device and a method, which is individual to a patient, treat malignant diseases by using selectively acting tumor-destructive mechanical pulses (TMI). The tumor-destructive pulse shapes and frequency are determined using physical cell properties, which are individual to each patient. The device is controlled in such that lethal pulse fields are applied in the tumor area.

Various systems and methods for controlling an ultrasonic surgical instrument according to the location of tissue grasped within an end effector are disclosed. A control circuit can be configured to apply varying power levels, via a generator, to an ultrasonic transducer driving an ultrasonic electromechanical system to oscillate an ultrasonic blade. Further, the control circuit can measure impedances of the ultrasonic transducer corresponding to the varying power levels and determine a location of tissue positioned within the end effector according to a difference between the impedances of the ultrasonic transducer relative to a threshold.

An apparatus capable of generating high power microwave frequency pulses for use with an electrosurgical device. The apparatus may be used for coagulating or ablating biological tissue. The apparatus includes an amplifier line-up comprising: a microwave signal generator for generating microwave radiation; a modulator arranged to pulse the microwave radiation; and an amplifier module arranged to increase the power of pulses of microwave radiation. The amplifier module works by providing a set of amplifiers that exhibit a gain that is greater than the total loss experienced at the components that divide the input signal and then combine the output signals. For example, if each amplifier in the array has a gain of 10 dBm, it is viable to use conventional power splitters and combiners to obtain an output microwave signal with substantially higher power than is provided by conventional electrosurgical generators.

A surgical instrument includes a shaft, an end effector extending distally from the shaft, and a housing extending proximally from the shaft. The housing includes a motor configured to generate at least one motion to effectuate the end effector, and a power source configured to supply power to the surgical instrument, wherein the power source includes a casing, a data storage unit, and a deactivation mechanism configured to interrupt access to data stored in the data storage unit. In addition, the power source includes a battery pack and a deactivation mechanism configured to deactivate the battery pack if the casing is breached.

Systems and methods for improving vision of a subject implanted with an intraocular lens (IOL). In some embodiments, a method of treating an ocular disease of a subject having an implanted intraocular lens (IOL) includes determining visual needs of a subject that are associated with an ocular disease of the subject determining a pattern of a plurality of pulses of radiation to apply, by refractive index writing, and applying the plurality of pulses of radiation to the one or more selected areas of the IOL.

Systems and methods for improving vision of a subject implanted with an intraocular lens (IOL). In some embodiments, a method includes applying a plurality of laser pulses to the IOL. The laser pulses can be configured to produce, by refractive index writing on the IOL, a predetermined change in phase profile of the IOL to increase spectacle independence.

Systems and methods for improving vision of a subject implanted with an intraocular lens (IOL). In some embodiments, a method includes determining at least one photic phenomenon experienced by the subject after implantation of the IOL; and applying a plurality of laser pulses to the IOL, the laser pulses being configured to produce, by refractive index writing on the IOL, a phase shift in the IOL to compensate for the photic phenomenon.

A calibration method for a hand-held surgical instrument is disclosed. The hand-held instrument includes a drive motor, a firing rod controlled by the drive motor and having at least one indicator, and a sensor configured to detect the at least one indicator. A microcontroller includes a pulse modulation algorithm stored therein to control the drive motor. The microcontroller executes a calibration algorithm to adjust at least one program coefficient in the pulse modulation algorithm.

Volumetrically oscillating plasma flows, the volume of which controllably expands and contracts with time, are disclosed. Volumetrically oscillating plasma flows are generated by providing an energy with a power density that changes with time to the plasma-generating gas to form a plasma flow. The changes in the energy power density result in plasma flow volumetric oscillations. Volumetric oscillations with a frequency of above 20,000 Hz results in ultrasonic acoustic waves, which are known to be beneficial for various medical applications. System for providing volumetrically oscillating plasma flows and a variety of surgical non-surgical applications of such flows are also disclosed.