A multiple drive interference screw device with a head having multiple insertion features. The screw component has a tubular body with a first end and a closed second end, and the head is positioned at the first end and configured to engage with a driver to advance the screw into the bone A penetrating tip is positioned at the second end. The head of the screw component has at least three insertion features, such as a hex shaped insertion feature around the major diameter of the head and a hexalobe shaped insertion feature within the hex shaped insertion feature, and a sprocket shaped insertion feature positioned exterior to the hex shaped insertion feature.

The disclosure provides systems and related methods for delivering a prosthesis to a target location. The system includes a tether delivery catheter and a prosthesis delivery catheter, and also can include a lock delivery catheter or knot pusher, as desired. Various embodiments of useful valve prostheses are also disclosed.

A suture anchor method including a suture anchor and a suture anchor drive. The suture anchor is positionable on a rod of the suture anchor drive. The rod defines an awl for forming a hole in a bone. The suture anchor drive further has an impactor for moving the suture anchor along the rod between a retracted position and an advanced position so as to implant the suture anchor in the bone with the awl positioned in the bone.

The invention relates to tissue anchor in medical procedures. More specifically the invention relates to a tethered anchor. The tethered anchor includes a tether portion (108) that is elongate and extends between a first end and a second end, the tether portion being formed of a flat film construct; and an anchor portion (106) that defines a width that is greater than a width of the tether portion, the anchor portion being integrally formed with the tether portion of the flat film construct and extending continuously from the second end of the tether portion, the anchor portion having a first aperture (402) through which the tether portion extends.

Various implementations of a bone anchoring assembly comprise a bone anchor and an insert. The bone anchor comprises a proximal end a distal end an outer profile suitable for defining a firm and stable coupling with the bone tissue, and a seat open at the proximal end, in which the seat defines an axis. The insert defines an axis that is suitable for being received in the seat of the bone anchor and comprises a proximal end a distal end and one or more eyelets placed at the proximal end. Moreover, the seat and the insert comprise snap coupling means suitable for axially retaining the insert in the seat and suitable for allowing the free rotation of the insert in the seat around the axis of the insert.

The disclosure provides systems and related methods for delivering a prosthesis to a target location. The system includes a tether delivery catheter and a prosthesis delivery catheter, and also can include a lock delivery catheter or knot pusher, as desired. Various embodiments of useful valve prostheses are also disclosed.

A method of treating diastolic heart failure includes implanting a cardiac implant in a heart of a subject diagnosed as suffering from diastolic heart failure. A superior portion of a flexible tether of the cardiac implant is anchored to one or more left-atrial sites of one or more walls of the left atrium. An inferior portion of the flexible tether is anchored to a site of a wall of a mid third of the left ventricle, of a wall of an apical third of the left ventricle, and/or of a papillary muscle of the left ventricle. As a result, the flexible tether reduces a volume of the left atrium during at least a portion of ventricular diastole of each cardiac cycle, thereby enhancing ventricular filling. Other embodiments are also described.

A stitching anchor nail includes an anchor body in a shape of straight tube, a non-circular blade jack formed in and through an axis portion of the anchor body along an axis direction thereof, a thread-in structure at a rear-end part of the anchor body, and a spiral tooth structure formed on a side surface of the anchor body and extending from a rear-end part toward a front end of the anchor body along a spiral direction. The spiral tooth structure is formed with a tooth-in entrance at a front end thereof and has a cross section in a shape of a trapezoid having an included angle ranging from 45 to 55 degree between two side edges of the trapezoid and has a tooth top in a width ranging from 0.4 to 0.7 mm.

A system and method comprising an anchor assembly including an anchor and a locking element, a tensionable fixation member (e.g., surgical suture, tape, etc.), and a release member, wherein the anchor further comprises a first end, second end and anchor body. This re-tensionable anchor is designed to be implanted into bone. One end of a suture or other tensionable fixation member is attached to the tissue on one end to assist with fixation of soft tissue. Once the anchor has been seated in the bone, the second end of the suture or tensionable fixation member is pulled through a “one-way only” passage in body of the anchor. When the tensionable fixation member enters the body of the anchor, it traverses past by bending or deflecting out of the way a locking element within the anchor that will permit passage of the suture and will stay in contact with the fixation member via elastic compression that results from the elastic bending or deflection but prevent it from passing back. This continuous locking on the suture creates fixation security, allows for optimal tensioning, and prevents loosening in the opposite direction. An instrument designed to reach the locking element and deliberately bend or deflect it will allow for loosening the suture to provide for the ability to readjust the tension to the operator's liking.

An example anchor-manipulation tool includes (i) at a distal portion of the tool, an anchor-engaging element and an actuator, (ii) at an extracorporeal proximal portion of the tool, a controller, and (iii) a flexible longitudinal member extending between the proximal portion and the distal portion. The distal portion of the tool can be transluminally advanced to an anchor that is intracorporeally implanted in a subject. Subsequently, the anchor-engaging element can be engaged with an eyelet defined by a head of the anchor. Subsequently, the controller can be used to transition the tool into an articulatably-coupled state in which: (i) the eyelet at least in part inhibits movement of the anchor-engaging element away from the anchor, and (ii) the distal portion of the anchor-manipulation tool is deflectable with respect to the anchor. Subsequently, the anchor can be de-anchored by using the anchor-manipulation tool to apply a de-anchoring force to the eyelet.