Extra-urethral implants and methods of use are disclosed. Implants can treat disorders or diseases of the prostate by, for example, enlarging the lumen of the prostatic urethra.

Devices, systems and methods for retracting, lifting, compressing, supporting or repositioning tissues, organs, anatomical structures, grafts or other structures within the body of human or animal subjects for the purpose of treating a diseases or disorders and/or for cosmetic or reconstructive purposes and/or for research and development purposes or other purposes.

Extra-urethral implants and methods of use are disclosed. Implants can treat disorders or diseases of the prostate by, for example, enlarging the lumen of the prostatic urethra.

The devices and methods can provide short-term strength and rigidity and long-term stability and support after a bone and/or ligament injury in a single procedure. An orthopedic fixation device may include a body having a first end, a second end, and a length therebetween. The body may include a first portion, a second portion and a shaft portion disposed between the first portion and the second portion. The shaft portion may include one or more bioabsorbable materials. The body may include an internal channel disposed along the length. The device may also include a suture being disposed within the internal channel.

The present disclosure relates generally to the field of medical devices for delivering artificial chordae tendineae in a patient. A system for adjusting tension in an artificial chordae tendineae includes an artificial chordae tendineae coupleable between a clip and an anchor. The clip is engageable with a leaflet of a heart valve while the anchor is engageable with a papillary muscle or heart wall. The anchor includes a body portion, and a locking portion coupleable with the artificial chordae tendineae and configured to allow movement of the artificial chordae tendineae in a first direction while preventing movement of the artificial chordae tendineae in a second direction opposite the first direction. An actuator is coupled to the locking portion for selectively releasing the locking portion to enable selective movement of the artificial chordae tendineae in the second direction.

Apparatus for attaching a first object to a second object, the apparatus comprising a distal anchor comprising a generally cylindrical body and a vertical bore extending through the generally cylindrical body; a proximal anchor comprising a generally cylindrical body, a first vertical bore extending through the generally cylindrical body, a second vertical bore spaced distally from the first vertical bore parallel to the first vertical bore, a third vertical bore spaced distally from the second vertical bore parallel to the first vertical bore, and a fourth vertical bore spaced distally from the third vertical bore parallel to the first vertical bore; and a suture having a proximal end and a distal end, with an enlargement formed at the distal end, wherein the suture extends through the vertical bore, through the fourth vertical bore, through the third vertical bore, through the second vertical bore and through the first vertical bore.

Bone anchors having improved fixation are discussed. The bone anchors include an anchor body and radially protruding ribs that extend approximately parallel to a longitudinal axis of the bone anchor. A leading distal edge of each rib may be configured in a tapered knife-edge configuration. Such ribs may mitigate the plow-out effect, preserving contact between the ribs and the surrounding bone along the length of the anchor. Furthermore, such ribs provide increased surface area, improving fixation strength.

A method of repairing a heart valve provides intravascular access for repair of a heart valve through a ventricular trans-septal approach. An external guide catheter can be inserted through a vein of a patient into the right ventricle via the right atrium. An internal guide catheter can be inserted through the external guide and can provide access to the septum for a puncture tool to create an opening through the septum to the left ventricle. The internal guide can then be advanced into the left ventricle and used to guide a deployment catheter that deploys a repair device onto the heart valve.

A clip includes a first side portion and a second side portion fastenable together and configured to attach to a broad suture. The first side portion has a first aperture sized to permit passage of the broad suture therethrough. The second side portion has a second aperture sized to permit passage of the broad suture therethrough, and at least one prong in the second aperture configured to penetrate the broad suture. A stopper surface is provided on the first side portion, wherein the prong contacts the stopper surface when the first side portion and the second side portion are fastened together so as to maintain the prong in the broad suture to thereby attach the clip to the broad suture.

An adjustable anchor system provides for securing tissue to bone and includes an anchor with a collapsible suture loop affixed thereto and a tissue suture connected to the collapsible suture loop. After the tissue suture is loaded into the tissue and the anchor implanted into the bone the collapsible loop is collapsed to tension the tissue suture.