An endovascular system employs a lever structure to deploy an embolic device at a target site in the vasculature of a patient. The endovascular system comprises an elongate tubular member provided with a lever structure and an elongate detachment wire to assert an effort to the proximal portion of a lever member outwardly, thereby generating a load to the distal portion of the lever member inwardly to allow the lever structure to engage and secure the embolic device. The elongate detachment wire is disengageable from the lever structure to remove the effort asserted to the proximal portion of the lever member, thereby removing the load off the distal portion of the lever member to allow the lever structure to disengage and release the embolic device.

Disclosed are implantable medical devices for the occlusion of a bodily lumen, cavity, vessel, or organ, as well as methods for manufacturing such occlusion devices, and methods for treating a subject using the occlusion devices. The devices generally include a wire having shape memory properties and a flexible membranous material disposed about the wire. Some embodiments include a lateral fringe on the membranous material. Some embodiments include a fluid capture cup affixed to the wire.

An implant for occluding a left atrial appendage may include an expandable framework including a body portion and a disk portion, wherein the expandable framework is configured to shift between a collapsed configuration and an expanded configuration, and an occlusive disk element disposed within the disk portion. The disk portion may include a first disk portion integrally formed with the body portion, and a second disk portion movably attached to the first disk portion by at least one hinge member.

Various aspects of the present disclosure are directed toward systems, methods, and apparatuses that include an occlusion device having a barrier member. The barrier member may include an enlargeable portion and a tail portion extending from the enlargeable portion. The enlargeable portion and the tail portion are releasably coupled to the delivery catheter such that the tail portion is radially unsupported and collapsible upon deployment.

An occlusive implant may include an expandable framework configured to shift between a collapsed configuration and an expanded configuration, the expandable framework including a proximal end and a distal end. The expandable framework includes a plurality of anchor members extending radially outward from the expandable framework in the expanded configuration, each anchor member including a root portion fixedly attached to the expandable framework and extending distally to a trunk portion in the expanded configuration. At least a portion of the trunk portion extends radially outward relative to the root portion in the expanded configuration. At least one of the plurality of anchor members includes a plurality of branches extending radially outward from the trunk portion in the expanded configuration.

Thrombectomy devices, systems and methods for extraction of vascular thrombi from a blood vessel.

A method of occluding an aneurysm includes positioning a braided implant within an aneurysm sack such that an outer non-inverted layer contacts a wall of the aneurysm and an inverted layer apposes the outer non-inverted layer to form a double layer of braid across a neck of the aneurysm. A radiopaque end of the braided implant can be positioned centrally within the aneurysm so that the radiopaque end extends adjacent or across a plane defined by a fold between the outer non-inverted layer and the inner inverted layer. Embolic coils can be inserted into the aneurysm sac and inhibited from exiting the aneurysm at the neck by the double layer braid across the aneurysm neck.

Systems and methods for treating an aneurysm in accordance with embodiments of the present technology include intravascularly delivering an occlusive member to an aneurysm cavity via an elongated shaft and transforming a shape of the occlusive member within the cavity. The method may include introduction of an embolic element to a space between the occlusive member and an inner surface of the aneurysm wall. In some embodiments, the elongated shaft is detachably coupled to a distal portion of the occlusive member.

A tubular braided implant is provided including a braid that can be delivered as a single layer braid, invert into itself during deployment to form at least two nested sacks and include additional braid material that can fill the innermost sack. The additional braid material can loop or coil like a ribbon and/or invert to form smaller and smaller nested sacks. The braid can have a variable braid angle along its length such that when positioned for delivery, the can have a high braid angle near its distal end and a low braid angle near the proximal end. In addition, or as a replacement for the braid material that fills the innermost sack, the implant can include an embolic coil that can loop within the innermost sack.

A device for occluding a vasculature of a patient including a micrograft having an absorbent polymeric structure with a lumen of transporting blood. The micrograft has a series of peaks and valleys formed by crimping. The occluding device is sufficiently small and flexible to be tracked on a guidewire and/or pushed through a microcatheter to a site within the vasculature of the patient. Delivery systems for delivering the micrografts are also disclosed.