Devices, systems, and methods used to seal a treatment area to prevent embolic agents from migrating are described. The concept has particular benefit in allowing liquid embolic to be used with a variety of intravascular therapeutic applications, including for occluding aneurysms and arteriovenous malformations in the neurovasculature.

Devices and methods divert blood flow from a first vessel to a second vessel and maintain blood flow in the first vessel. The device includes a first segment and a second segment. The first segment is configured to anchor in the first vessel. The first segment includes a window to allow blood to flow into the first segment, through the window, and distal in the first vessel. The second segment is configured to anchor in the second vessel. The second segment is configured to allow blood to flow into the first segment, through the second segment, and into the second vessel.

A system for treating heart disease, such as pulmonary hypertension or right heart failure, including an implantable component and external components for monitoring the implantable component is provided. The implantable component may include a compliant member, e.g., balloon, coupled to a reservoir via a conduit. Preferably, the compliant member is adapted to be implanted in a pulmonary artery and the reservoir is adapted to be implanted subcutaneously. The external components may include a clinical controller component, monitoring software configured to run a clinician's computer, a patient monitoring device, and a mobile application configured to run on a patient's mobile device.

Provided herein is an apparatus having a first tubular body, a second tubular body disposable within the first tubular body, a first plurality of fenestrations in fluid communication with a gallbladder lumen, and an expandable body disposed around the first plurality of fenestrations. The first plurality of fenestrations is configured to deliver a phase changing ablation medium by spraying the phase changing ablation medium in a spatially diffuse pattern into the space defined by the expandable body between the first plurality of fenestrations and the wall of the gallbladder. The first tubular body and the second tubular body define an annular flow path. A pressure sensor measures intraluminal pressure of the gallbladder. A control unit is coupled to the pressure sensor.

Some embodiments of a system or method for treating heart tissue can include a control system and catheter device operated in a manner to intermittently occlude a heart vessel for controlled periods of time that provide redistribution of blood flow. In particular embodiments, the system can be configured to provide an estimation of the cumulative effects of the treatment. For example, some embodiments of the system or method can treat myocardium that is at risk of infarction by intermittently altering blood flow in a venous system to induce microcirculation within the myocardium, and can output a cumulative dosage value indicative of a measurement of progress of reducing an infarct size.

Disclosed are implantable medical devices for the occlusion of a bodily lumen, cavity, vessel, or organ, as well as methods for manufacturing such occlusion devices, and methods for treating a subject using the occlusion devices. The devices generally include a wire having shape memory properties and a flexible membranous material disposed about the wire. Some embodiments include a lateral fringe on the membranous material. Some embodiments include a fluid capture cup affixed to the wire.

The disclosure provides for a device and method for dilation. The dilation device may include a catheter body having a proximal portion and a distal portion, a dilation expandable body in fluid communication with a first opening on the distal portion of the catheter body, and an occlusion anchor expandable body in fluid communication with a second opening on the distal portion of the catheter body. The method for dilating a stricture site may include inserting the dilation device into a stricture site of a patient, expanding the occlusion anchor expandable body at the stricture site, and expanding the dilation expandable body at the stricture site.

The present invention provides a percutaneous vascular surgical system for performing endovascular/neurovascular interventions, the system incorporating a sheath having a proximal end and a distal end and defining a main lumen extending between the proximal and distal ends, an auxiliary lumen also defined by the sheath, a reversibly inflatable balloon located about the sheath adjacent the distal end and in fluid communication with the auxiliary lumen, a syringe selectively connectable to the main lumen to create suction through the main lumen, and a vessel closure device for the closure of the arteriotomy, the surgical system and method of the invention having utility in a large number of percutaneous vascular procedures such as carotid artery stenosis or neurovascular interventions and enabling four procedures to be performed with one system, being percutaneous access, emboli removal, flow reversal and arteriotomy closure.

Systems, apparatus, and methods are described for treatment of varicocele and associated conditions. In some embodiments, systems, apparatus, and methods described herein can include forming one or more fluid connections or fistulas between blood vessels such as a gonadal vein (e.g., spermatic vein, ovarian vein) and surrounding veins. In some embodiments, systems, apparatus, and methods described herein can include occluding one or more blood vessels such as a gonadal vein (e.g., spermatic vein, ovarian vein). In some embodiments, systems, apparatus and methods described herein relate to flow diverters, replacement valves, etc., e.g., for treatment of varicocele and associated conditions.

The invention relates to an infusion catheter device. This catheter device 10 has an elongate, substantially tubular shape defining a longitudinal axis, a distal end (D) and a proximal end (P), configured to be introduced into a conduit (50) having an inner wall (54) and an outer wall (56) and comprising at least one partial or total obstruction (60) or occlusion to be treated, said device comprising, at its distal end (D), one or more infusion orifices (16, 18, 20, 22) for an infusion liquid (LI), and, upstream from the one or more infusion orifices, at the proximal side (P) of the infusion catheter (10), at least one obturating element (70) for temporary obturating, configured to treat said obstruction (60) or occlusion and to perform the infusion of the infusion liquid (LI) downstream from the obturating element (70) and in the obturating position. This device is suitable in particular for cardiac surgery and interventional cardiology.