An elongate resilient tube of a mesh of shape memory alloy is used to therapeutically occlude an opening in body tissue. The tube is compressible so that it can be delivered to the opening in the body within a catheter. The tube self-expands as it is released from the catheter to contiguously form, sequentially, the following shapes: an outer bell-shaped structure; an inner bell-shaped structure disposed within the outer bell-shaped structure to conformingly engage an inner side of the outer bell-shaped structure; a tubular connector having a diameter substantially smaller than the inner bell-shaped structure, the tubular connector extending away from an apex of the inner bell-shaped structure; an inner plate-shaped structure; an outer plate-shaped structure; and a releasable connector. The bell shape is placed on one side of the opening, and the plate shape is placed on the other side of the opening, the connector passing through the opening.

An intracorporeal space filling device and a delivery system and method for using the device is disclosed. The space filling device is preferably configured for percutaneous delivery from a peripheral conduit of a patient. The space filling device has an elongated tubular or interconnected bead structure which may have a transmutable material disposed within it. The transmutable material can be altered from a non-rigid state to a rigid state by the application of various types of energy or by other suitable means. The space filling device can be positioned by a delivery system and detached from the delivery system after desired positioning is achieved.

An occluding device apparatus includes an embolization coil with a distal end and a proximal end with an opening and an attacher that is threaded through the opening at the proximal end of the embolization coil. The apparatus further comprises a delivery kit for delivery of the embolization coil in a body cavity. The kit comprises a guide catheter for percutaneous introduction of the embolization coil and an inner catheter slidably disposed within the guide catheter during insertion. The inner catheter comprises a proximal end and a distal end. The inner catheter further includes a hub disposed adjacent the proximal end. The kit further comprises a guide wire slidably disposed within the inner catheter. The guide wire provides a path during insertion thereof within a body cavity. The kit further comprises a pushwire to advance the embolization coil through the inner catheter.

Embodiments of the present disclosure are configured to assess effectiveness of an endovascular aneurysm coiling procedure. A system is provided that can include a flow-sensing intravascular device with a flexible elongate member which is sized and shaped for insertion into a vasculature, and a flow sensing element secured to a distal portion of the flexible elongate member. A computer can be in communication with the flow-sensing intravascular device. With a coil is positioned within an aneurysm, the computer can detect a flow measurement of fluid entering the aneurysm based on data obtained by the flow sensing element positioned within the aneurysm, and can determine that the fluid flow measurement is at or below an acceptable level. If flow is at an unacceptable level, additional coils can be added to further restrict flow. Also, a second source of fluid into the aneurysm can be indicated by the flow measurements.

An assembly at a proximal end of an intravascular delivery system can allow the proximal end of a pull wire to move independently of a delivery tube. The assembly can generally include the pull wire, the delivery tube, a feature to prevent the proximal end of the pull wire from becoming inaccessible due to distal movement of the pull wire, and a feature to protect the proximal end of the pull wire from inadvertent, premature manipulation. When the intravascular delivery system is navigating tortuous vasculature, the proximal end of the pull wire can move distally in relation to the proximal end of delivery tube, relieving stress on the distal end of the pull wire. The proximal end of the pull wire can be protected from inadvertent manipulation during delivery and made available for manipulation once the distal end of the delivery system is in place.

An endoscopic treatment tool set includes: an endoscopic treatment tool that includes a sheath having a lumen, an elongated shaft inserted into the lumen and the elongated shaft having an insertion passage, a stylet disposed in the insertion passage, an implant connected to the stylet, and a manipulation part provided at the sheath; and a jig. The endoscopic treatment tool is packed together with the jig. The jig is coupled to a proximal end portion of the stylet disposed in the manipulation part and the jig is configured to be movable relative to the manipulation part. The implant is connected to the jig via the stylet, and the implant is configured such that the jig is pulled toward a proximal end side of the manipulation part so that the stylet is moved to a proximal end side in the insertion passage and the implant is loaded in the insertion passage.

A lung volume reduction system is disclosed comprising an implantable device adapted to be delivered to a lung airway of a patient in a delivery configuration and to change to a deployed configuration to bend the lung airway. The invention also discloses a method of bending a lung airway of a patient comprising inserting a device into the airway in a delivery configuration and bending the device into a deployed configuration, thereby bending the airway.

A vasculature occlusion device detachment system including a heating element of a predetermined resistivity. A coil securing suture terminates in a proximal bead retained within the heating element while the distal end of the coil securing suture extends beyond the distal end of the heating element and is attached to the proximal end of the vasculature occlusion device. The coil securing suture is independently rotatable of the heating element 360 degrees about a longitudinal axis extending therethrough the heating element. A power source applies electrical current to the heating element via an electrically conductive corewire and separate insulated electrically conductive wire to increase its resistance and, as a result of the heat produced, sever the coil securing suture.

Disclosed herein are devices, designs, methods of manufacturing and using medical devices comprising expandable bodies for treating saccular vascular aneurysms and occluding segments of blood vessels and other biological conduits. Exemplary expandable bodies include hollow gold structures that can be folded, wrapped, and compressed, joined to a delivery device, advanced to location in the body of patient in need of treatment, expanded by injection of a fluid into the central void, and separated from the delivery device, remaining in place in an open, expanded form without the addition of support structures to the central void. Other expandable bodies include coiled wires that can be loaded into delivery catheters and expelled from the delivery catheters using pusher devices. Also disclosed herein, are methods of using multiple medical devices and expandable bodies where the expandable bodies are placed adjacent to each other to occlude a saccular aneurysm.

A device for occluding a vasculature of a patient including a micrograft having an absorbent polymeric structure with a lumen of transporting blood. The micrograft has a series of peaks and valleys formed by crimping. The occluding device is sufficiently small and flexible to be tracked on a guidewire and/or pushed through a microcatheter to a site within the vasculature of the patient. Delivery systems for delivering the micrografts are also disclosed.