Disclosed herein is a bowl-shaped neck bridge with a distal-facing concavity and a central lumen. The neck bridge is inserted and expanded within a cerebral aneurysm. The, embolic members (such as embolic coils, embolic ribbons, or string-of-pearls embolic strands) are inserted through the central lumen into the aneurysm sac.

An endovascular device, including an elongated flexible sheath defining a lumen with an inner opening sized for enabling selective advancement of an endovascular instrument therethrough, the sheath having at least a first region and a second region; an electrode within the first region of the sheath; and a constrictor associated with the first region of the sheath, the constrictor being configured, while at least the first region and the second region of the sheath are positioned within a body and in response to an input received from outside the body, to reversibly narrow the lumen of the sheath in an area adjacent the electrode to thereby bring the electrode into contact with an adjacent portion of the endovascular instrument.

A distal portion (16) of an elongated body (12) is configured to mate with a distal portion (20) of an interface member (18) mechanically connected to an embolization device (22). The embolization device (22) is additionally attached to the elongated body (12). The elongated body distal portion (16) and the interface member proximal portion (19) may collectively define a protrusion and a recess configured to receive the protrusion to provide the mating. The elongated body (12), interface member (18), and embolization device (22) may be configured for delivery to a vasculature target site, and manipulation of the deployed embolization device (22) may be facilitated by the mating between the elongated body (12) and the interface member (18).

Retrieval of material from vessel lumens can be improved by use of a distal element comprising an expandable mesh. a treatment device includes an elongated member having a proximal portion and a distal portion configured to be positioned within a blood vessel at a treatment site at or near a thrombus. A distal element comprising a plurality of woven filaments defining a shaft at a proximal portion and a body distal of the shaft is coupled to the distal portion of the elongated member via a connection assembly. In an expanded state, at least a portion of the distal element is configured to be in apposition with the blood vessel wall at the treatment site to anchor or stabilize the elongated member with respect to the blood vessel. The distal element can be electrically coupled to an extracorporeal current generator.

An implantable medical device includes an elongate member having a cross-sectional dimension that is less than 0.00085 inch, wherein the elongate member is made from a material comprising a platinum-tungsten alloy having a percentage of tungsten that is at least 10% by weight or alternatively the implantable medical device includes an elongate member made from a material comprising an alloy containing rhenium.

There is provided herein a non-occlusive blood restricting device for treating a vascular malformation, the blood restricting device consisting of a wire comprising a first section configured to be coiled into a first coil when deployed within the vascular malformation; wherein the first coil comprises a spiral or sequence of loops, the spiral or sequence of loops having a gradually decreasing diameter; and wherein the first coil is configured to line a neck and/or a wall of the vascular malformation so as to at least partially cover an orifice thereof, and a second section configured to be deployed within a blood vessel, adjacent the vascular malformation; wherein the second section is configured to form a second coil, circumferentially lining a wall of the blood vessel.

An implant including an open end and a pinched end can have a predetermined shape. When in the predetermined shape, the tubular braid can include a proximal inversion and two segments, and the braid can be composed of one or more wires. The first segment can extend from the open end of the tubular braid to the proximal inversion. The second segment can be at least partially surrounded by the open end and extend from the proximal inversion to the pinched end. The tubular braid can also include at least one corrugated fold. The one or more corrugated folds can be located within the first segment, second segment, or both. The corrugated folds can be configured to assist in anchoring the example device when in the implanted shape within an aneurysm in a similar manner to stent struts to help the tubular braid hold its shape.

Methods, devices, and systems for mechanically reducing the volume of the lung. Some embodiments include endobronchially positioning an anchoring device within a lung, the anchoring device comprising at least a distal anchor, expanding at least a portion of the distal anchor to anchor the distal anchor against lung lumen tissue, and tensioning at least a portion of the device to reduce the volume of the lung.

Treatment of an aneurysm or other vascular defect can be facilitated or enhanced by an implant delivered with a thermally activated detachment system. A delivery system can include an implant with a proximal portion that defines a port. A pusher device can include arms extending distally from a junction of the pusher device and through the port, with distal sections of the arms disposed within the implant. The arms can, at a certain temperature, transition from engagement with the implant to a shape that facilitates release of the implant. Additionally or alternatively, a coil can engage an outer surface of the implant at the proximal portion and transition to a shape that facilitates release of the implant.

Delivery and detachment of an implant can be enhanced by a retraction mechanism to secure portions of a delivery wire within an interior space of the implant. A delivery system can include an implant having a proximal end portion. A delivery wire can include (i) a detachment zone proximal to the proximal end portion and (ii) a distal region distal to the proximal end portion. An expansion member can be located between the proximal end portion and the distal region of the delivery wire. The expansion member can be biased to move the distal region of the delivery wire distally away from the proximal end portion when severed at the detachment zone.