A braided vaso-occlusive member formed out of first plurality of filaments interwoven with a second plurality of filaments, wherein filaments of the first plurality are helically wound in a first rotational direction along an elongate axis of the braided member, and filaments of the second plurality are wound in a second rotational direction opposite the first rotational direction, such that filaments of the first plurality cross over and/or under filaments of the second plurality at each of a plurality cross-over locations axially spaced along the elongate axis of the braided member, wherein at each cross-over location, the filaments of the first plurality cross over at least two consecutive filaments of the second plurality, then cross under only a single filament of the second plurality, and then cross over at least two additional consecutive filaments of the second plurality.

An apparatus includes a plurality of beads a linking assembly joining the beads together. The beads and the linking assembly are arranged in an annular arrangement and sized to form a loop around an anatomical structure in a patient. The loop may move between a contracted and expanded configuration. The loop is magnetically biased toward the contracted configuration by a magnetic bias of the beads. Each bead includes a housing having a first piece and a second piece that together define a magnetic chamber. A magnetic is within the magnetic chamber. A weld joins the first piece and the second piece while hermetically sealing the magnet chamber. The first piece of the housing includes a mounting feature integrated with a surface of the first piece. The mounting feature mates with a fixture to constrain the first piece of the housing as the weld is formed.

A method of manufacturing a bead assembly for a sphincter augmentation device includes initiating 3D printing of a unibody housing such that the unibody housing defines a first opening, a chamber, and a magnet chamber. The method further includes pausing the 3D printing process, inserting a magnet within the magnetic chamber, and then resuming 3D printing of the unibody housing to form a hermetic seal between the magnet chamber and an external surface of the unibody housing.

An apparatus includes a plurality of beads and a linking assembly joining the beads together. The beads include a first bead having a first external contact surface, and a second bead having a second external contact surface. A magnet is contained within the housing. The beads and the linking assembly are arranged in an annular arrangement and sized to form a loop around an anatomical structure in a patient. The loop may move between a contracted and expanded configuration. The loop is magnetically biased toward the contracted configuration by a magnetic bias of the beads. The first external contact surface and the second external contact surface engage each other as the loop transitions into the contracted configuration to drive the first bead and the second bead into a predetermined orientation relative to each other about the linking assembly in the contracted configuration.

Hemostasis systems and related methods are generally described. In some embodiments, a hemostasis system may include an inflatable intrauterine balloon. The balloon may be configured to apply pressure to a patient's uterus to reduce the risk of postpartum hemorrhage. In some embodiments, the balloon may be inserted at least partially into the uterus and inflated. A support, which may be located inside the balloon, may expand from a contracted configuration to an expanded configuration to help maintain the balloon's position relative to the cervix when the balloon is inflated. In some embodiments, the support may contract with and/or due to deflation of the balloon, allowing the balloon to move out of the uterus. The balloon may be covered with a hemostatic covering (e.g., gauze preloaded with a hemostatic agent such as hexatomic acid) to enhance the balloon's hemostasis properties.

Embolic coils with detachable segments that are separated by detachment capsules that are thermolytically degradable such that varying lengths of coil may be implanted into a vascular malformation to occlude same. The capsules are radiotransparent when compared to the adjoining coil segments to the location of the segments is easily seen. The capsules further include protruding electrical contacts that make positive contact with terminals on a delivery catheter. The terminals on the delivery catheter serve as markers so the relationship between the detachment capsules and the terminals is easily visible under x-ray.

A method for treating a genetically associated chronic obstructive pulmonary disease. At least one implant is advanced into an airway of a lung having a genetically associated chronic obstructive pulmonary disease. The at least one implant is delivered into the lung to increase tension of the lung and thereby improve breathing function of the lung.

Body lumen occlusion apparatus and methods are described.

An intracorporeal space filling device and a delivery system and method for using the device is disclosed. The space filling device is preferably configured for percutaneous delivery from a peripheral conduit of a patient. The space filling device has an elongated tubular or interconnected bead structure which may have a transmutable material disposed within it. The transmutable material can be altered from a non-rigid state to a rigid state by the application of various types of energy or by other suitable means. The space filling device can be positioned by a delivery system and detached from the delivery system after desired positioning is achieved.

An aneurysm embolization device can include a body having a single, continuous piece of material that is shape set into a plurality of distinct structural components. For example, the device can have an expandable component and an atraumatic tip portion extending therefrom. Further, the tip portion can be configured to enable the device to be implanted within the aneurysm while tending to mitigate risk of puncturing the aneurysm dome or otherwise assist in framing the aneurysm in advance of placement of additional embolic material.