Apparatus, systems, and methods are provided for monitoring AF episodes, delivering ATP pulses, and/or achieving electrical isolation of the left atrial appendage (LAA) of a patient's heart and/or preventing thrombus formation after electrical isolation. For example, devices are provided that may implanted from within the left atrium, e.g., to isolate the LAA, prevent thrombus formation within the LAA, facilitate endothelialization, and/or deliver pacing.

The present methods, systems, and devices relate to an occlusion device for blocking a biological tube, the biological tube being prone to a peristaltic wave having a wave length, and where the occlusion device comprises at least two sections, where each section is connected by at least one narrowing to at least one other section. The occlusion device is of an elastic material, and each section is configured to deform when a force is applied by the peristaltic wave, and the length of at least one of the at least two sections corresponds substantially to the wave length of the peristaltic wave in the biological tube, so as to absorb the peristaltic wave. The methods, systems, and devices relates to reversible contraception of female and/or male gendered species intervening with biological tube, which are responsible for transportation of fertility fluids, such as the transportation of spermatozoes or oocytes in for example the human reproductive system.

A reinforcement device is described. This reinforcement device may include mesh elements (such as two mesh elements) arranged in a sequence and spatially offset from each other along a sequence direction, where a given mesh element includes a sack having a mesh wall, an opening defined by a border, and an orientation along a normal direction perpendicular to the opening. Moreover, the reinforcement device may include one or more connectors, where a given connector has a length and is mechanically coupled to adjacent mesh elements in the sequence. Note that the one or more connectors may be configured to or may allow the orientation of the given mesh element to change, independent of orientations of a remainder of the mesh elements, by rotating about a longitudinal direction in a plane of the opening and perpendicular to the orientation.

The invention relates to an implant for vascular applications that can be transported by means of a catheter and is intended in particular to influence the blood flow in the area of arteriovenous malformations, such as fistulas and aneurysms, to fill the saclike dilation of the malformation, promote thrombus formation and cover the neck of the malformation. The implant according to the invention is provided with an occlusion unit (1, 13) having a three-dimensional shape constructed from several subunits (5a, 14) from a framework of struts (5, 16, 17), with a covering, preferably a membrane (6), being located between struts (5, 16, 17).

Disclosed herein is an intrasacular aneurysm occlusion device with a proximal bowl-shaped mesh which covers the neck of an aneurysm sac and a distal globular mesh between the proximal bowl-shaped mesh and the dome of the aneurysm sac. The proximal bowl-shaped mesh blocks blood flow into the aneurysm sac and the distal globular mesh holds the bowl-shaped mesh in place against the aneurysm neck.

A plugging device, including a first part, and a second part connected to the first part. The first part or the second part includes a plurality of braiding filaments and a gathering member; portions of the braiding filaments that are close to one ends of the braiding filaments cooperate to form a disc face. The plugging device further includes a film member. The film member at least covers part of an outer surface of the disc face; the gathering member includes an inner sleeve and an outer sleeve, both of which are hollow and sleeved; and one end of each braiding filament and at least part of a gathering region of the film member are all fixed to the gathering member.

A packaging for an implant to hold the implant in a first condition. The packaging including a first packaging tube and a container, wherein the implant is movable from the container into the first tube and maintained within the first tube in a second condition, the implant having a first transverse dimension in the first condition and a second transverse dimension in the second condition, the second transverse dimension being less than the first transverse dimension.

A system for treatment of an aneurysm includes an intrasaccular device that can be delivered using a catheter. The device can include at least one expandable structure adapted to transition from a compressed configuration to an expanded configuration when released into the aneurysm. The expandable structure can have a specific shape or porosity. Multiple expandable structures can also be used, in which case each of the expandable structures can have a unique shape or porosity profile. The morphology of the aneurysm and orientation of any connecting arteries can determine the type, size, shape, number, and porosity profile of the expandable structure used in treating the aneurysm.

Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).

An embodiment of the invention includes an expandable implant to endovascularly embolize an anatomical void or malformation, such as an aneurysm. An embodiment is comprised of a chain or linked sequence of expandable polymer foam elements. Another embodiment includes an elongated length of expandable polymer foam coupled to a backbone. Another embodiment includes a system for endovascular delivery of an expandable implant (e.g., shape memory polymer) to embolize an aneurysm. The system may include a microcatheter, a lumen-reducing collar coupled to the distal tip of the microcatheter, a flexible pushing element detachably coupled to an expandable implant, and a flexible tubular sheath inside of which the compressed implant and pushing element are pre-loaded. Other embodiments are described herein.