A BFRT cuff and portable electric pump system and a method for exercising using said cuff. The method incudes providing a BFRT cuff and a portable electric pump system, placing the BFRT cuff on a limb of a user, connecting the BFRT cuff to the portable electric pump system, selecting a pressure value or percent of limb occlusion pressure (LOP), causing the portable electric pump system to supply air to the BFRT cuff until the LOP of said limb is obtained, terminating air flow to the BFRT cuff and then reducing the pressure in the BFRT cuff, disconnecting the BFRT cuff from the portable electric pump system, and exercising the limb of the user while the BFRT cuff is at a selected pressure or a selected percent of LOP.

Methods and apparatus are provided for assessing endothelial function in a mammal. In certain embodiments the methods involve applying to the artery a substantially constant external pressure that causes the tension in the arterial wall to be reduced, where the pressure is provided via a cuff adjacent to and/or around a region of the mammal's body; determining, over the course of one or more cardiac cycles, changes in pressure in the cuff resulting from cardiac activity of the mammal to establish a baseline value for a parameter related to endothelial function in the mammal; applying a stimulus to the mammal; determining, over the course of one or more cardiac cycles, changes in pressure in the cuff resulting from cardiac activity of the mammal to establish a stimulus-effected value for a parameter related to endothelial function in the mammal; wherein the baseline value is determined from measurements made when the mammal is not substantially effected by the stimulus; and wherein differences in the baseline value and the stimulus-effected value provide a measure of endothelial function in the mammal.

Radial artery compression devices with an inflatable chamber and a substantially rigid frame are disclosed. The inflatable chamber of the radial artery compression devices can be inflated and then deflated according to a predetermined protocol. Some substantially rigid frames can form a wall of the inflatable chamber. Some substantially rigid frames can include indicia to facilitate positioning of the inflatable chamber relative to a puncture site of a patient.

Systems and methods and devices are provided for treating conditions such as heart failure and/or pulmonary hypertension by at least partially occluding flow through the superior vena cava for an interval spanning multiple cardiac cycles. A catheter with an occlusion device is provided along with a controller that actuates a drive mechanism to provide at least partial occlusion of the patient's superior vena cava, which reduces cardiac filling pressures, and induces a favorable shift in the patient's Frank-Starling curve towards healthy heart functionality and improved cardiac performance. The occlusion device may include a lumen obstructed by a relief valve that may permit fluid flow through the occlusion device to release an excessive build-up of pressure.

[Object] To provide a hemostasis aid and a tourniquet by which a blood vessel at a puncture site can be more reliably distended.

[Solving Means] A hemostasis aid 1 includes a tourniquet 10 including a plurality of pressurizing layers 11a to 11e divided in a width direction and a control device 20 that pressurizes the pressurizing layers 11a to 11e sequentially from the pressurizing layer 11a on one end side A in the width direction W to on the other end side B. Accordingly, a puncture site can be reliably distended by wrapping the tourniquet 10 such that the puncture site is positioned on a patient's distal side with respect to the other end side.

An inflatable belt 100 for use in a BFR system with an outer belt material 102 hermetically sealed to an inner belt material 101 along a perimeter, thereby forming at least one inflatable chamber 103, the inflatable chamber having an input port 104 for accepting a gas into the chamber, the inflatable belt further comprising a first fastening means 110 in communication with the outer belt material, for attaching to a second fastening means 111 in communication with the outer belt material, thereby locking a circumference of the inflatable belt, when wrapped around a user's limb.

A wearable system comprises tourniquets. Each of the tourniquets comprises an inflatable chamber, and is configured to occlude blood flow in an artery of a wearer. The wearable system comprises compressed gas sources in fluid communication with the inflatable chamber of the tourniquets. The wearable system comprises valves. Each of the valves comprises an input in fluid communication with one of the compressed gas sources, and an output in fluid communication with the inflatable chamber of one of the tourniquets. The wearable system comprises fixed pressure regulators. Each of the fixed pressure regulators is in fluid communication with the valves, and is configured to regulate a pressure of the compressed gases delivered to the inflatable chamber of at least one of the tourniquets. The wearable system comprises switches. Each of the switches is configured to operate one of the valves.

A modular wound treatment system includes a central modular hub having a modular connection for one or more pneumatically-actuated, modular components, such as a pneumatically-actuated soft robotic gripper component configured to curve and at least partially encircle the wound when actuated and thereby apply direct pressure to the wound, and a pneumatically-actuated tourniquet component configured to apply pressure proximal to the wound to limit the flow of arterial blood to the wound. The system also includes a pressurized gas supply in pneumatic communication with the modular connection, sensors for measuring the amount of pressure being applied by the pneumatically-actuated, modular components, a display for providing system information, and a controller for controlling the system. Methods of treating a wounded subject using the system are also provided.

A remotely operated blood flow occlusion or restriction cuff for use as a muscle building device or a compact medical emergency reperfusion tourniquet. A module on the cuff housing an air pump, a controller operating the air pump and power supply. The inflation and deflation of the cuff controlled using a smart device in communication with the controller. In the preferred embodiment this is via a Smartphone app and Bluetooth protocol. The tourniquet operating in conjunction with a Doppler ultrasound and/or pulse oximeter to monitor arterial inflow.

Embodiments of the present invention are directed to devices, systems and methods adapted for implementing intermittent displacement of blood to mitigate peripheral nerve neuropathy such as that induced by chemotherapeutic agents (i.e., chemotherapy-induced neuropathy (CIN)) that are administered to a patient. Such devices, systems and methods advantageously provide for precise, uniform and controlled blood flow occluding (and optionally blood displacing) compression along irregular surfaces of an appendage of a patient. Such precise, uniform and controlled blood occluding compression is imparted upon the epidermal and dermis skin layers within the aforementioned areas of a patient's extremities to decrease the time that free nerve endings located in the epidermal and encapsulated nerve endings located in the dermis skin layers are exposed to nerve damaging chemotherapy chemicals, thereby substantially decreasing CIN caused by prolonged exposure to such chemicals.