The invention includes a transradial introducer sheath support and integral hemostasis device. The device includes a wristband and an introducer sheath support mount attached to the wristband. The wristband is made from a flexible and resilient material that is applied to the distal forearm of the patient or other desired location on the patient. The support mount may be a molded unitary structure, such as made from a thermoplastic material, and is attached directly to the outer surface of the wristband. An inflatable hemostatic element is incorporated in the wristband and mounted to an interior surface of the wristband. The hemostatic element may be selectively inflated to apply pressure to a radial access point of the patient during and after removal of the transradial introducer sheath from the patient. Another embodiment provides a hemostatic element by a rotatable clasp of the sheath support mount.

Aspects of the present disclosure are directed toward providing enhanced structural support to an organ. As may be implemented in accordance with one or more embodiments, an apparatus includes structure configured and arranged to partially encircle a tubular organ, having a semi-cylindrical shape with a tapered end and blunt end of the cylinder. A gap region provides a region of the organ that is unrestricted/unsupported. Struts/lattice facilitate ingrowth of tissue, and couple the apparatus to the organ, which allows the apparatus to provide support/restrict flow in the organ without necessarily coupling to any other structure (e.g., with the majority or all of the support provided via the apparatus as coupled onto and terminating on a sidewall of the tubular organ).

A brain injury reduction system provides a protective measure to reduce severity of brain injury caused by collision or blast. A sensing device of the system detects an impending or occurring event (e.g., collision or blast) in an environment surrounding the individual and sends information about the event to a controller of the system. The sensing device can be stationary or moves with the individual. Based on the information, the controller determines whether the event will likely cause brain injury to the individual. If so, the controller sends an instruction to an actuation device of the system to activate the protective measure. The actuation device uses transcutaneous electrodes to electrically simulate glottis closure and contraction of the abdominal musculature to induce a Valsalva-like maneuver. The Valsalva-like maneuver can increases the stiffness of the brain tissues in the intracranial compartment, and thus reduces the susceptibility of the brain tissues to deformation.

A device for performing a remote ischemic conditioning treatment. The device includes an inflatable cuff and a cartridge which is a source of gas for inflating the cuff. A first valve controls the flow of gas from the cartridge to the cuff so as to maintain a predetermined pressure in the cuff during an ischemic period. A second valve allows gas to escape from the cuff during a reperfusion period of the remote ischemic conditioning treatment. A controller which may be battery-powered is used to control the opening and closing of the valves. The cartridge may contain a gas, or materials which, under certain conditions, react to produce a gas. The chemical reaction may be initiated by an electrical pulse or signal from the controller.

The invention provides methods for reducing traumatic injury through the use of ischemic conditioning.

A system for performing remote ischemic conditioning includes an inflatable cuff configured to encircle a limb of a subject and a controller removably attached to the cuff. The controller includes a pump; a manifold in fluid communication with the pump; a connector in fluid communication with the manifold and in removable fluid communication with the inflatable cuff; a pressure sensor; and a control circuit configured to implement a remote ischemic conditioning treatment protocol.

There is provided a method for controlling a flow of sperms in a uterine tube formed by a uterine tube wall of a patient. The method comprises gently constricting (i.e., without substantially hampering the blood circulation in the uterine tube wall) at least one portion of the uterine tube wall to influence the flow of sperms in the uterine tube, and stimulating the constricted wall portion to cause contraction of the uterine tube wall portion to further influence the flow of sperms in the uterine tube. The method can be used for restricting or stopping the flow of sperms in the uterine tube, or for actively moving the fluid in the uterine tube, with a low risk of injuring the uterine tube.

A compression device can include an adjustable belt, an inflation bladder, and a control module. The adjustable belt can be sized to fit circumferentially around a subject's abdomen. The inflatable bladder and the control module can be secured to the belt. The control module can include a housing that encloses at least one of a pump, a pressure relief valve, and a controller. The pump and the pressure relief valve can be in fluid communication with the bladder. The pump can be configured to inflate the bladder to a pre-determined pressure and apply a compressive pressure to the subject's abdomen. The pressure relief valve can be configured to decrease the pressure within the bladder. The controller can be configured to automatically adjust the compressive pressure in response to a change in the subject's posture. The controller can be in electrical communication with the pump and the pressure relief valve.

A pressure adjustment unit of a hemostatic instrument includes a main container portion connected to a side of a balloon and an auxiliary balloon serving as an expansion member. The main container portion has, for example, air passing holes for permitting a portion of a fluid (air) to be expelled. A sliding member is installed at the main container portion and is movable along the main container portion from a state in which the air passing holes of the main container portion are blocked to a state in which one or more of the hole are open, and a moving body movable inside the main container portion to successively block the air passing holes opened by moving the sliding member.

Monitoring vital parameters of a wearer of a compression garment by analyzing a pressure signal waveform indicative of a fluid pressure in an inflatable and deflatable bladder of the compression garment. Analyzing the pressure signal waveform for an oscillating amplitude as a function of time and/or a representation of a pulse of the wearer provides an indication of blood pressure of the wearer.