Systems and methods for removal of clot material from vessel lumens are disclosed. A medical device assembly can include a catheter having a lumen and a distal portion configured to be positioned at or adjacent a treatment site within a vessel. An expandable member has a first portion coupled to the distal portion of the catheter, and a second portion extending away from the catheter distal portion. An elongate shaft extends through the lumen of the catheter, and the second portion of the expandable member is releasably coupled to the shaft. When the shaft is slidably moved relative to the surrounding catheter, the second portion of the expandable member can be released from the shaft, and the shaft can be withdrawn or removed.

A method of penetrating an intravascular occlusion including the steps of: obtaining an apparatus with a sleeve assembly defining an elongate passageway having a lengthwise axis, a stabilizing assembly, and a blade assembly; directing the sleeve assembly into an operative position within a vessel passage wherein an outlet from the elongate passageway is adjacent an occlusion within the vessel passage; through the stabilizing assembly, stabilizing the sleeve assembly in the operative position; and with the sleeve assembly stabilized in its operative position advancing the blade assembly in a first lengthwise direction relative to the sleeve assembly to penetrate the occlusion.

The present disclosure is directed a method of facilitating treatment via a vascular wall defining a vascular lumen containing an occlusion therein. The method may include providing a first intravascular device having a distal portion and at least one aperture and positioning the distal portion of the first intravascular device in the vascular wall. The method may further include providing a reentry device having a body and a distal tip, the distal tip having a natural state and a compressed state and inserting the distal tip, in the compressed state, in the distal portion of the first intravascular device. The method may further include advancing the distal tip, in the natural state, through the at least one aperture of the first intravascular device.

The present disclosure is directed to a device. The device may include a distal shaft defining a central lumen and an orienting element comprising at least one inflatable member. Wherein a first portion of the orienting element extending from the shaft in a first direction and a second portion of the orienting element extending from the shaft in a second direction. Further, wherein the second direction is substantially opposite the first direction.

Apparatus, including a guidewire, having a distal end dimensioned to penetrate into a nasal sinus and a balloon, which is fitted over the guidewire in proximity to the distal end. There is an inflation channel, which runs along the guidewire and is coupled to convey a pressurized fluid into the balloon so as to inflate the balloon. The apparatus also includes a first electrode, fixedly attached to a distal tip of the guidewire, and a second electrode, fixedly attached to the guidewire at a location proximal to the distal tip. There are conductive leads running along the guidewire and coupled to apply an electrical potential between the first and second electrodes.

The present disclosure is directed to a device. The device may include a distal shaft defining a central lumen and an orienting element comprising at least one inflatable member. Wherein a first portion of the orienting element extending from the shaft in a first direction and a second portion of the orienting element extending from the shaft in a second direction. Further, wherein the second direction is substantially opposite the first direction.

A medical apparatus includes a guidewire and a fixator catheter. The fixator catheter comprises a tubular body with a distal portion and a proximal portion, and further includes a distal opening, a fixator secured to the distal portion, and a body opening arranged between the fixator and the proximal portion. The guidewire passes through the body opening and the distal opening of the fixator catheter. The fixator is movable between a compact configuration and an expanded configuration and, in the expanded condition, is capable of anchoring the guidewire and fixator catheter in a lumen of a blood vessel.

A rotary catheter for opening partially and totally obstructed bodily vessels of varying diameter (e.g., blood vessel) which comprises a motor-driven flexible hollow shaft rotatably disposed in a flexible tube, an aspiration channel defined between the flexible tube and the hollow shaft, a tip affixed to a distal end of the hollow shaft having a rounded distal end being rotatable and slideable over the guidewire, the tip having sides, a base and a crown that is offset away from a longitudinal axis of the hollow shaft further than the base and a distance between the sides being smaller than a distance between the crown and the base leaving open passages along the tip, the guidewire can be withdrawn proximally to allow the rotating crown to displace the distal end of the tip away from said wall of said vessel to tunnel through a total obstruction.

The present invention provides a catheter for treating occlusions in blood vessels. An exemplary catheter for treating occlusions in blood vessels comprises a tubular inner member including a base segment with a first lumen defining a fluid inlet port, and a second lumen defining a fluid outlet port. An extension segment is distal to the base segment. The extension segment has a reduced cross-section. An emitter assembly includes a first insulated wire extending through the second lumen and a second insulated wire, and a conductive sheath wrapped circumferentially around the first insulated wire, the second insulated wire, and the extension segment. A cap or balloon is sealably attached to the distal end of the catheter and surrounds the emitter assembly, said cap or balloon being fillable with conductive fluid.

Apparatus, including a guidewire, having a distal end dimensioned to penetrate into a nasal sinus and a balloon, which is fitted over the guidewire in proximity to the distal end. There is an inflation channel, which runs along the guidewire and is coupled to convey a pressurized fluid into the balloon so as to inflate the balloon. The apparatus also includes a first electrode, fixedly attached to a distal tip of the guidewire, and a second electrode, fixedly attached to the guidewire at a location proximal to the distal tip. There are conductive leads running along the guidewire and coupled to apply an electrical potential between the first and second electrodes.