A rotational atherectomy device for removing a stenotic tissue from the iliac artery of a patient. The device comprises a flexible, rotatable drive shaft having an elongated proximal portion, an elongated distal portion. An abrasive element is mounted to the drive shaft between the elongated proximal and distal portions of the drive shaft and between and spaced away from a pair of counterweights which are mounted to said elongated portions of the drive shaft. The eccentric abrasive element and the counterweights are configured for rapid rotation together with the drive shaft, the drive shaft is configured to extend throughout an entire length of the iliac artery to be treated. One elongated portion of the drive shaft extends out of the patient through a first access opening located in a femoral artery which is ipsilateral to the treated artery. Another elongated portion of the drive shaft extending through a second access opening located in another peripheral artery of the patient. A method of treating an iliac artery of a patient using such a rotational atherectomy device.

A method of treating a lesion in a body lumen to enlarge a passageway in the lumen including providing a cutting member, connecting a tracking member to the cutting member to form an assembly, inserting the connected cutting member and tracking member through a first lumen of a catheter, withdrawing the catheter from the cutting member and tracking member, inserting the catheter over the tracking member and leaving the cutting member outside the catheter, and expanding a portion of the catheter to move the cutting member into cutting contact with the lesion. A device for treating a lesion in a body lumen including a cutting member having a coupler to connect a tracking member is also provided.

A capturing unit provided on a distal end of a second tube can be deformed into a contracted state and an expanded state, in which the capturing unit is deployed to form a capturing chamber. The capturing chamber has an opening area decreased as it goes from a distal end opening of the capturing chamber toward a proximal end opening of the capturing chamber. A third tube rotatable relative to the second tube and a cutting unit provided on a distal end of the third tube for cutting a foreign substance are arranged in a second lumen. In the expanded state of the capturing unit, the cutting unit is arranged more toward the proximal end opening of the capturing chamber than the distal end opening.

Systems and devices are described which include a tissue cutting device including a tethering component; an elongated flexible cutting component having a first end and a second end, the first and the second end of the elongated flexible cutting component secured to the tethering component; at least one tether having a first end and a second end, the first end of the at least one tether attached to the elongated flexible cutting component, the second end of the at least one tether operably coupled to the tethering component, the tethering component configured to at least one of extend and retract the at least one tether; and a motor operably coupled to the tethering component, the motor including circuitry configured to rotate the tethering component and the secured elongated flexible cutting component; wherein extension and retraction of the at least one tether by the tethering component changes a shape formed by the elongated flexible cutting component.

The present disclosure relates to a mechanical thrombectomy device that includes a catheter assembly with a basket assembly formed of a proximal hub and a distal hub; a flexible tube having a first end attached to the proximal hub and a second end attached to the distal hub; and a plurality of basket wires. The flexible tube may be laser-cut to allow for bending, elongation, and compression. The basket wires each have a first end attached to the proximal hub and a second end attached to the distal hub. The basket wires are disposed around the flexible tube and configured to expand to a preset shape. The basket assembly is attached to a distal end of a rotatable shaft. A drive assembly is configured to rotate the rotatable shaft to rotate the basket assembly. The basket assembly when rotated is configured to macerate a material proximate to the basket assembly.

An intravascular device, such as s guidewire device, includes a hollow proximal section and a hollow distal section joined to the proximal section and extending distally from the proximal section to form a continuous lumen extending from a proximal end of the device to a distal end of the device. An inner member extends from the proximal end to the distal end and is joined to the distal end. The inner member is translatable within the lumen in response to applied tension. At least the distal section includes a micro-fabricated cutting pattern that enables deflection of the distal end in response to the application of tension to the inner member.

The present invention is related to scoring or cutting balloon catheters carrying at least on a portion of their surface at least one drug or drug preparation and at least one lipophilic antioxidant at a ratio of 3-100% by weight of the at least one lipophilic antioxidant in relation to 100% by weight of the drug, wherein a combination of the at least one drug being a limus drug and the at least one lipophilic antioxidant being butylated hydroxytoluene is excluded.

A device suitable for removing material from a living being is provided, featuring at least an aspiration pump, powered by a motor. The aspiration pump and any optional infusate pump preferably feature a helical pumping mechanism, and operate at a high rate of rotation, thereby ensuring adequate pumping performance and flexibility. The helical pumping mechanism may be a helical coiled wire about a central core tube. The helical coil wire, whether together with, or independent of, the core tube, may be rotated to cause a pumping action. Additionally, a narrow crossing profile is maintained, ensuring that the device may reach more tortuous regions of the vasculature. In one embodiment, the system comprises a wire-guided mono-rail catheter with a working head mounted on a flexible portion of the catheter that can laterally displace away from the guide wire to facilitate thrombus removal. The working head may be operated to separate and move away from the guide wire to come within a closer proximity of the obstructive material to more effectively remove it from the vessel.

A medical device is disclosed for cutting substances inside a body lumen. The medical device includes: a drive shaft that is rotatable; at least one strut that is rotatably connected to a distal side of the drive shaft, the at least one strut extending along a rotation axis, and wherein a central portion of the at least one strut is bent so as to be expandable radially outwardly; and a support portion that is rotatably connected to the distal side of the drive shaft, and wherein the support portion is formed in a mesh shape and a tubular shape while including multiple gaps, at least a portion of which is positioned on a radially inside of the at least one strut, and which is expandable radially outwardly by a central portion in a direction extending along the rotation axis being bent.

An apparatus for cutting a wall of a vessel (V), such as scoring or slicing a lesion (L) associated therewith. The device includes a cutter (10) with a single shaft (12) having a branched portion including at least two radially expandable arms. A first (16) of the expandable arms includes at least one blade (20) for slicing or scoring the lesion (L) when expanded. A second (18) of the expandable arms may also include a blade (20), or may have no blade. A sheath (S) may also be provided. The arm or arms with blades may also include a limiter (22) for limiting the cutting depth of the blade (20). An anchor may also be provided for anchoring the cutter (10) in the vessel (V).