Rotational atherectomy devices and systems can remove or reduce stenotic lesions in blood vessels by rotating one or more abrasive elements within the vessel. The abrasive elements are attached to a distal portion of an elongate flexible drive shaft that extends from a handle assembly that includes a driver for rotating the drive shaft. In particular implementations, the handle assembly encapsulates an electric motor assembly, a pump assembly, and a controller assembly.

Retrieval assemblies configured to capture an obstruction located in a bodily duct of a patient and associated methods of manufacture are provided. According to one implementation a retrieval assembly is provided that includes a distal collar fixed stationary on an elongate wire, a proximal collar slideable along a portion of the length of the elongate wire, and a plurality of shape memory elongate capturing elements that each has a proximal end coupled to the proximal collar and a distal end coupled to the distal collar. The retrieval device is configured to automatically transition from a radially constrained state to an expanded rest state with the proximal collar located nearer the distal collar when in the expanded rest state. As the retrieval device transitions from the radially constrained state to the expanded rest state, proximal portions of the capturing elements invert around the proximal collar.

Rotational atherectomy devices and systems can remove or reduce stenotic lesions in blood vessels by rotating one or more abrasive elements within the vessel. The abrasive elements are attached to a distal portion of an elongate flexible drive shaft that extends from a handle assembly that includes a driver for rotating the drive shaft. In particular implementations, the handle assembly encapsulates an electric motor assembly, a pump assembly, and a controller assembly.

Rotational atherectomy devices and systems can remove or reduce stenotic lesions in blood vessels by rotating one or more abrasive elements within the vessel. The abrasive elements are attached to a distal portion of an elongate flexible drive shaft that extends from a handle assembly that includes a driver for rotating the drive shaft. In particular implementations, the handle assembly encapsulates an electric motor assembly, a pump assembly, and a controller assembly.

An adjustable loop stripper for stretching an arterial wall outwardly as plaque is excavated inwardly.

Rotational atherectomy devices and systems can remove or reduce stenotic lesions in blood vessels by rotating one or more abrasive elements within the vessel. The abrasive elements are attached to a distal portion of an elongate flexible drive shaft that extends from a handle assembly that includes a driver for rotating the drive shaft. In particular implementations, the handle assembly encapsulates an electric motor assembly, a pump assembly, and a controller assembly.

A cutting balloon catheter with concealed blades is provided. A pressure channel communicated with the balloon is formed by a gap between the outer tube and the inner tube. The cutting assembly includes first support rings sleeved on the outer tube and a blade group, the first support rings are capable of generating radial elastic deformation and sliding freely. The push-pull tube is sleeved on the outer tube, and the protective bag is configured to encapsulate the balloon and the cutting assembly. When the cutting assembly is pushed to the balloon, after the balloon is expanded, the blade group cuts a section of the protective bag opposite to the balloon to expose the blade group. The catheter can pass through the complex and tortuous blood vessels to reach the lesion site, and realize effective cutting while reducing the damage to the blood vessels.

Systems and methods are provided for altering the shape of a target tissue structure of a subject, e.g., a nasal septum or other nasal tissue that include securing a first end of a shaping element to tissue adjacent the structure; manipulating the tissue to alter a shape of the structure; and applying a force to the shaping element to maintain the altered shape of the structure.

A method and apparatus for treating a clot in the blood vessel of a patient, and particularly the treatment of a pulmonary embolism is disclosed. The treatment includes restoring flow through the clot followed by clot removal, either partially or substantially completely. The clot treatment device is expandable into the blood vessel and may contain radial extensions that assist in restoring flow as well as in removing clot material.

Methods and apparatus are provided to facilitate the minimally invasive removal of tissue biopsies and to facilitate the direct approach to anesthetizing the chest wall, in accordance with embodiments of the present invention. A pull-type cutting device 1 comprises two coaxially nested tubes, each extending from a proximal end 21 to a distal end 22. The first tube 61 defines a guide wire lumen 23 for slidingly receiving a guide wire. The second tube 63 extends over the first tube 60 and coupled thereto at the distal end 22 defining an expandable portion 13 adjacent the distal end 22. The second tube 63 defines an inflation lumen 25 extending from the shaft proximal end 21 to the expandable portion 13. The inflation lumen 25 communicates inflation fluid from the proximal end 21 to the expandable portion 13 so as to inflate and deploy the expandable portion 13. Disposed adjacent the shaft distal end 22 is a cutting head 10 comprising the expandable portion 13 having a cutting portion 11 distal from the shaft distal end 22.