A treatment system includes a fluid cooling supply system for chilling and delivering liquid coolant to a patient. The fluid cooling supply system includes a cooling device and a heat exchanger device. The heat exchanger device is biased to the cooling device and is in fluid communication with a treatment device in a patient. The fluid cooling supply system includes at least one biasing mechanism to provide a given biasing force between the heat exchanger device and the cooling device to effectuate and improve heat transfer. The liquid coolant may be circulated through an energy delivery device positioned in an airway of a patient to preserve tissue. The system is controlled to circulate liquid coolant at a given temperature and pressure for a selected amount of time during pulmonary treatment of a patient.

The invention relates to ablation catheter electrodes that solve in part the problem of tissue charring during radiofrequency ablation. The electrode assemblies of the invention include passageways that lead from the inner lumen of the assemblies to the surface of the assemblies, wherein the passageways have a smooth conjunction with the outer surface. These smooth conjunctions comprise rounded edges or are chamfered. In the case of rounded edges, the rounded edges can have fixed radii of about 0.002 to about 0.008.

Devices for therapeutic nasal neuromodulation and associated systems and methods are disclosed herein. A system for therapeutic neuromodulation in a nasal region configured in accordance with embodiments of the present technology can include, for example, a shaft and a therapeutic element at a distal portion of the shaft. The shaft can locate the distal portion intraluminally at a target site inferior to a patient's sphenopalatine foramen. The therapeutic element can include an energy delivery element configured to therapeutically modulate postganglionic parasympathetic nerves at microforamina of a palatine bone of the human patient for the treatment of rhinitis or other indications. In other embodiments, the therapeutic element can be configured to therapeutically modulate nerves that innervate the frontal, ethmoidal, sphenoidal, and maxillary sinuses for the treatment of chronic sinusitis.

A surgical instrument (10, 100) configured to facilitate gripping and manual adjustment by a left-handed or righted-handed user. The surgical instrument includes a rod (11) having a first end (12a) attachable to a working end (13, 113) of the instrument via a mount (16). The rod has a second end (12b) coupled to a handle (14) having rotational directionality for gripping by a first hand of the user. The handle is rotatable about the rod so as to allow the user to adjust an angular displacement of the user's finger relative to the working end, and a locking member (20, 146) prevents rotation of the handle relative to the rod when the beveled indent is optimally located relative to the working end.

Skin treatment apparatus comprising an energy applicator structure configured to establish heating or ablation at a predetermined and controllable (i.e. selectable) depth below a surface of skin tissue with which it is in contact. The applicator structure may receive a cooling medium and microwave frequency electromagnetic energy, which provide a combined treatment effect that results in heating or ablation in a zone beneath the skin surface. The applicator may be a waveguide (e.g. waveguide horn antenna) with internal shielding configured to provide a substantially uniform heating effect. The applicator may include a thermal camera to monitor treatment.

The invention relates to ablation catheter electrodes that solve in part the problem of tissue charring during radiofrequency ablation. The electrode assemblies of the invention include passageways that lead from the inner lumen of the assemblies to the surface of the assemblies, wherein the passageways have a smooth conjunction with the outer surface. These smooth conjunctions comprise rounded edges or are chamfered. In the case of rounded edges, the rounded edges can have fixed radii of about 0.002 to about 0.008.

Cooling systems for medical probe assemblies are provided. For example, a cooling system comprises a pump assembly including a control unit having a controller, a motor, and a pump head driven by the motor; a fluid reservoir; a lumen for delivering a cooling fluid to the medical probe assembly distal end; tubing extending through the pump head for conveying the cooling fluid from the fluid reservoir to the lumen; and a flow sensor for sensing the cooling fluid flow rate. The pump head is disposed between the fluid reservoir and the medical probe assembly to pump the cooling fluid from the fluid reservoir to the lumen. The flow sensor is disposed between the pump head and the medical probe assembly to sense the cooling fluid flow rate. Methods for controlling fluid flow rate through a cooling circuit and systems for using a plurality of medical probe assemblies also are provided.

A laser treatment system comprising a plurality of laser devices disposed on a cart, a combiner coupled to the plurality of laser devices, the combiner configured to combine a plurality of laser signals from the plurality of laser devices into a single conducting medium and a treatment head coupled to the conducting medium, the treatment head configured to deliver the plurality of laser signals to a predetermined location.

A system comprises a teleoperated manipulator, a manually operated instrument, and a position sensor coupled to the manually operated instrument. The position sensor is configured to generate pose information for the manually operated instrument. The system further comprises a controller configured to map a pose of the manipulator to a fixed world reference frame based on three-dimensional pose information for the manipulator known internally within the system. The controller is further configured to map a pose of the manually operated instrument to the fixed world reference frame based on the pose information for the manually operated instrument.

A medical device for ablation of a target tissue is disclosed. The medical device includes a catheter assembly attached to a balloon for the ablation of the target tissue. The catheter assembly includes a proximal end and a distal end. The catheter assembly includes a plurality of individual shafts placed concentrically or adjacent to each other. Further, the plurality of individual shafts includes a respective lumen, wherein the lumens of the plurality of individual shafts can be configured to supply radio frequency (RF) energy to an RF transmitter placed inside the balloon and also to serve as the passageway for a fluid to travel within the balloon. The fluid flowing within the lumens of the catheter assembly can further help in expanding the balloon and transferring energy from the RF transmitter within the balloon to the ablation site via a plurality of windows attached.