Devices for therapeutic nasal neuromodulation and associated systems and methods are disclosed herein. A system for therapeutic neuromodulation in a nasal region configured in accordance with embodiments of the present technology can include, for example, a shaft and a therapeutic element at a distal portion of the shaft. The shaft can locate the distal portion intraluminally at a target site inferior to a patient's sphenopalatine foramen. The therapeutic element can include an energy delivery element configured to therapeutically modulate postganglionic parasympathetic nerves at microforamina of a palatine bone of the human patient for the treatment of rhinitis or other indications. In other embodiments, the therapeutic element can be configured to therapeutically modulate nerves that innervate the frontal, ethmoidal, sphenoidal, and maxillary sinuses for the treatment of chronic sinusitis.

Devices for therapeutic nasal neuromodulation and associated systems and methods are disclosed herein. A system for therapeutic neuromodulation in a nasal region configured in accordance with embodiments of the present technology can include, for example, a shaft and a therapeutic element at a distal portion of the shaft. The shaft can locate the distal portion intraluminally at a target site inferior to a patient's sphenopalatine foramen. The therapeutic element can include an energy delivery element configured to therapeutically modulate postganglionic parasympathetic nerves at microforamina of a palatine bone of the human patient for the treatment of rhinitis or other indications. In other embodiments, the therapeutic element can be configured to therapeutically modulate nerves that innervate the frontal, ethmoidal, sphenoidal, and maxillary sinuses for the treatment of chronic sinusitis.

Devices for therapeutic nasal neuromodulation and associated systems and methods are disclosed herein. A system for therapeutic neuromodulation in a nasal region configured in accordance with embodiments of the present technology can include, for example, a shaft and a therapeutic element at a distal portion of the shaft. The shaft can locate the distal portion intraluminally at a target site inferior to a patient's sphenopalatine foramen. The therapeutic element can include an energy delivery element configured to therapeutically modulate postganglionic parasympathetic nerves at microforamina of a palatine bone of the human patient for the treatment of rhinitis or other indications. In other embodiments, the therapeutic element can be configured to therapeutically modulate nerves that innervate the frontal, ethmoidal, sphenoidal, and maxillary sinuses for the treatment of chronic sinusitis.

A method for forming a resonating structure within a body lumen, the method including advancing a flexible microwave catheter into a body lumen of a patient, the flexible microwave catheter including a radiating portion at the distal end of the flexible microwave catheter, the radiating portion configured to receive microwave energy, and at least one centering device proximate the radiating portion configured to deploy radially outward from the flexible microwave catheter; positioning the radiating portion near tissue of interest; deploying the at least one centering device radially outward from the flexible microwave catheter within the body lumen such that a longitudinal axis of the radiating portion is substantially parallel with and at a fixed distance from a longitudinal axis of the body lumen near the targeted tissue; and delivering microwave energy to the radiating portion such that a circumferentially balanced resonating structure is formed with the body lumen.

A medical instrument includes a shaft, an inflatable balloon and a Radiofrequency (RF) ablation electrode. The shaft is configured for insertion into a body of a patient. The inflatable balloon is coupled to a distal end of the shaft. The RF ablation electrode is disposed on an external surface of the balloon and has a distal edge configured to reduce electric field angular gradients of an RF electric field emitted from the distal edge.

A microwave delivery device, including a coaxial feedline having an inner conductor, an inner dielectric insulator coaxially disposed about the inner conductor, and an outer conductor coaxially disposed about the inner dielectric, and a radiating portion operably coupled to a distal end. The radiating portion includes a radiating portion inner conductor operable coupled to and extending from a distal end of the coaxial feedline inner conductor, a shielding outer conductor helically wrapped about the radiating portion inner conductor and operably coupled to the coaxial feedline outer conductor; and a shielding dielectric positioned between the radiating portion inner conductor and the shielding outer conductor wherein the width of the shielding outer conductor varies according to the longitudinal position thereof along the coaxial feedline inner conductor, and a cap operably coupled to a distal end of the radiating portion inner conductor and the shielding outer conductor to provide an electrical connection therebetween.

A microwave delivery device, including a coaxial feedline having an inner conductor, an inner dielectric insulator coaxially disposed about the inner conductor, and an outer conductor coaxially disposed about the inner dielectric, and a radiating portion operably coupled to a distal end. The radiating portion includes a radiating portion inner conductor operable coupled to and extending from a distal end of the coaxial feedline inner conductor, a shielding outer conductor helically wrapped about the radiating portion inner conductor and operably coupled to the coaxial feedline outer conductor; and a shielding dielectric positioned between the radiating portion inner conductor and the shielding outer conductor wherein the width of the shielding outer conductor varies according to the longitudinal position thereof along the coaxial feedline inner conductor, and a cap operably coupled to a distal end of the radiating portion inner conductor and the shielding outer conductor to provide an electrical connection therebetween.

A surgical device that includes a first support member extending along a longitudinal axis; a bladder located on the first support member; a first sealing member located on the bladder; and a second sealing member located on the bladder. The sealing member is located on one side of the longitudinal axis; and the second sealing member is located on another side of the longitudinal axis. The bladder is inflatable, and inflating the bladder changes a position of the first sealing member, the second sealing member, or both relative to the first support member.

Systems, delivery devices, and methods to treat to ablate, damage, or otherwise affect tissue. The treatment systems are capable of delivering energy to nerve tissue in a target region such that at least a portion of the nerve tissue is replaced by scar tissue or otherwise altered to inhibit reinnervation in the target region.

A system for modulating bladder function is disclosed. A system for evaluating the electrophysiological function of a bladder is disclosed. Methods for performing a controlled surgical procedure on a bladder are disclosed. A system for performing controlled surgical procedures in a minimally invasive manner is disclosed. An implantable device for monitoring and/or performing a neuromodulation procedure on a bladder is disclosed.