A system includes a catheter and an IRE pulse generator. The catheter includes an expandable frame fitted at a distal end thereof, the expandable frame including multiple electrodes configured to be placed in contact with a tissue in an organ of a patient, wherein a lateral distance between neighboring edges of any pair of adjacent electrodes is uniform along a longitudinal axis, and wherein the electrodes are configured to apply irreversible electroporation (IRE) pulses to tissue between pairs of the electrodes. The IRE pulse generator is configured to generate the IRE pulses.

Systems, devices, and techniques are disclosed for automatically detecting arrhythmia locations. The systems, devices, and techniques include a plurality of body surface electrodes configured to sense electrocardiogram (ECG) data. The systems, devices, and techniques include a processor including a neural network configured to receive a plurality of historical ECG data and corresponding arrhythmia locations determined based on each of the plurality of historical ECG data, train a learning system based on the plurality of historical ECG data and corresponding arrhythmia locations, generate a model based on the learning system. New ECG data may be received from the plurality of body surface electrodes and the processor may provide a new arrhythmia location based on the new ECG data. Additionally, a new coherent mapping adjustment may be provided based on a model that is trained using historical coherent mapping adjustments.

A system for ablation by electroporation including a catheter having electrodes, a display, and a controller. The controller is to generate, based on models of electric fields, graphical representations of the electric fields that can be produced using the electrodes, and overlay, on the display, the graphical representations of the electric fields and an anatomical map of a patient to aid in planning the ablation by electroporation, prior to delivering energy.

A system includes a catheter, a pulse generator and a controller. The catheter is configured for insertion into a body of a patient, and includes at least a first electrode, a second electrode and a third electrode, which are disposed at a distal end of the catheter and are configured to contact tissue within the body. The pulse generator is configured to apply one or more bipolar ablation pulses between the first and second electrodes, for ablating the tissue in contact with the first and second electrodes. The controller is configured to: (i) control the pulse generator to apply the one or more bipolar ablation pulses between the first and second electrodes, (ii) receive a signal indicative of a voltage, measured between the third electrode and a reference during application of the ablation pulses, and (iii) issue a notification in response to detecting that the voltage violates a predefined criterion.

In one embodiment, a catheter alignment system includes a catheter to be inserted into a body part, and including catheter electrodes to contact tissue at respective locations within the body part, a display, and processing circuitry to receive signals provided by the catheter, assess respective levels of contact of ones of the catheter electrodes with the tissue of the body part responsively to the received signals, find a direction in which the catheter should be moved to improve at least one of the respective levels of contact of at least one of the catheter electrodes responsively to the respective levels of contact of the ones of the catheter electrodes, and render to the display a representation of the catheter responsively to the received signals, and a direction indicator indicating the direction in which the catheter should be moved responsively to the found direction.

A system includes a display and a processor. The processor is configured to (a) receive multiple signals sensed by multiple electrodes of a multi-electrode catheter in a heart of a patient, (b) determine which of the electrodes are to be active in an ablation procedure, and (c) present the multiple signals to a user, on the display, using a graphical user interface (GUI) that (i) visualizes the signals from the electrodes determined to be active by a first graphical feature, and (ii) visualizes the signals from the electrodes determined not to be active by a second graphical feature, different from the first graphical feature.

The purpose of this invention is to provide pulsed field ablation (PFA)-based systems and devices for treating arrhythmia, which includes a pulsed voltage console, a pacing and ECG unit, and an ablation catheter. The pulsed voltage console is comprised of an electric pulse generator, a controller, a user interface(UI), and a converter. The pacing and ECG unit is comprised of an ECG recorder, a pacing catheter, a cardiac stimulator, and a mapping catheter. The pacing electric signal is transmitted to the pulsed voltage console. Voltage pulse delivery is synchronized to join pacing signal. Based on the pacing signal, a voltage pulse waveform is delivered during the refractory period of the cardiac cycle. The ablation catheter is connected to the system console through a converter, transferring the electric field energy to the tissue through electrodes on the ablation catheter. The ablation catheter includes a spline basket. The distal end of the spline basket is coupled with an annular catheter that can go into pulmonary vein (PV). Irreversible electroporation can be formed locally, linearly, or circularly, and evenly distributed over a large area, achieving the purpose of effectively treating atrial flutter, supraventricular tachycardia, atrial fibrillation, and other arrhythmias.

A balloon-type electrode catheter includes a catheter shaft, a balloon provided at a part including a distal end of the catheter shaft and being inflatable with a fluid, and an electrode. The balloon includes a through hole discharging a fluid in the balloon to an outside of the balloon, a distal end large diameter portion, a proximal end large diameter portion, a small diameter portion positioned between the two large diameter portions and being smaller in diameter than the two large diameter portions, a distal end inclined portion connecting the distal end large diameter portion and the small diameter portion, and a proximal end inclined portion connecting the proximal end large diameter portion and the small diameter portion. The electrode is exposed at at least the small diameter portion. The through hole is disposed in at least one of the distal end inclined portion or the proximal end inclined portion.

A balloon-type electrode catheter includes a catheter shaft including an outer shaft and an inner shaft, a balloon provided at a part including a distal end of the catheter shaft, and an electrode. The balloon includes an outer joining portion an inner joining portion, a distal end large diameter portion, a proximal end large diameter portion, a small diameter portion positioned between the two large diameter portions and being smaller in diameter than the two large diameter portions, a distal end inclined portion connecting the distal end large diameter portion and the small diameter portion, and a proximal end inclined portion connecting the proximal end large diameter portion and the small diameter portion. The electrode is exposed at at least the small diameter portion.

An ablation catheter including an elongate shaft, an inflatable balloon positioned at a distal region of the elongate shaft, a first ablation electrode disposed outside of and carried by an outer surface of the inflatable balloon, a first ultrasound transducer disposed outside of the inflatable balloon, and a flexible circuit. The flexible circuit includes a first conductor and a second conductor and is disposed outside of and carried by the outer surface of the inflatable balloon. The first conductor is in electrical communication with the first ablation electrode, and the second conductor in electrical communication with the first ultrasound transducer.