Systems and method for delivering and deploying an expandable stent to treat Intracranial atherosclerotic disease (ICAD) involving large and medium-sized blood vessels. The disclosed systems include a catheter, a shaft comprising a distal end disposed within the catheter, an expandable stent comprising a proximal end and a distal end, wherein the shaft is coupled to the expandable stent and the shaft is disposed within the expandable stent, and a plurality of struts, wherein a first end of each strut is coupled to the shaft and a second end of each strut is coupled to the expandable stent. Longitudinal movement of the shaft relative to the expandable stent extends the plurality of struts radially outward and expands the expandable stent, similar to umbrella. The plurality of struts provides radial force to the expandable stent in an expanded configuration to the vessel walls of the patient.

Using the disclosed intravascular devices it is possible to image tissues, deliver therapy, and evaluate the tissue after the therapy is delivered. One embodiment is a catheter configured to provide ultrasound imaging, drug delivery, and Doppler flow analysis. The devices can use ultrasound imaging as well as optical coherence tomography (OCT).

Tissue and vessel treatment devices and respective methods are provided. Devices comprise a flexible treatment layer that comprises a plurality of operable elements configured to be activated to apply the treatment to the obstruction upon bending of the flexible treatment layer beyond a specified curvature threshold and to be de-activated upon a specified decrease of the bending. The treatment layer may comprise optical fiber(s) with the operable elements as emission regions that emit electromagnetic radiation from the core upon bending the optical fiber beyond a specified bending threshold. Devices may be configured as vessel sealing tips for surgical forceps, in which the treatment layer is configured to yield vessel welding and vessel cutting effects.

An aspect of some embodiments of the application relates to a microcatheter comprising a deployment element disposed about around at least a portion of an exterior of a distal end of the microcatheter, the deployment element configured for repeatedly expanding and collapsing, the distal end arranged to allow forward or reverse axial displacement while the deployment element maintains a position, the deployment element arranged for positioning the microcatheter distal end approximately in the middle of a vessel.

The present invention generally relates to a flexible catheter device capable of being introduced into body passages, withdraw fluids therefrom or introduce fluids thereinto, and which includes electrodes configured to apply electrical signals in the body passage for carrying out thrombus dissolution and/or thrombectomy, wherein one of said electrodes is designed to contact the thrombus material and remove it or dissolve it, and wherein the electrical voltage signals are a unipolar pulsatile voltage signal.

A catheter system for treating a vascular lesion within or adjacent to a vessel wall within a body of a patient includes a single light source that generates light energy, a first light guide and a second light guide, and a multiplexer. The first light guide and the second light guide are each configured to selectively receive light energy from the light source. The multiplexer receives the light energy from the light source in the form of a source beam and selectively directs the light energy from the light source in the form of individual guide beams to each of the first light guide and the second light guide.

Systems and methods for creating an arteriovenous (AV) fistula comprise an elongate member, a distal member connected to the elongate member and movable relative to the elongate member, and a heating member disposed on at least one of the movable distal member and the elongate member. The distal member comprises structure for capturing tissue to be cut to create the fistula, and the heating member is adapted to cut through the tissue to create the fistula. The elongate member comprises an elongate outer tube. A shaft connects the distal member to the elongate member, and is extendable and retractable to extend and retract the distal member relative to the elongate member.

Provided is a radiofrequency balloon catheter system that allows inflation/deflation of the balloon in a controlled manner to enable the same to easily pass through the stenosis site without significantly changing the profile of a balloon (6). When a coolant is injected into the inside of the balloon (6), the balloon is inflated while discharging the coolant to the outside of the balloon (6), thus cooling the balloon (6) while applying a pressure to the balloon (6), with an intima being protected by perfusing the inside of the balloon (6) with a coolant. The radiofrequency balloon catheter system comprises a catheter shaft (1) comprising an inner tube shaft (3) and an outer tube shaft (2) that are slidable with each other; and a resilient balloon (6) that is inflatable and deflatable and provided between distal ends (4) of the inner tube shaft (3) and the outer tube shaft (2), said balloon (6) covering the inner tube shaft (3). The balloon (6) and the inner tube shaft (3) are in close proximity with each other to define a check valve (8). When the solution within the balloon (6) is suctioned to turn the pressure inside the balloon (6) to negative, the check valve (8) is closed and then the balloon (6) is deflated. Also, when a coolant is injected thereinto, the balloon (6) is inflated to open the check valve (8), thereby discharging the coolant to the outside. The radiofrequency balloon catheter system further includes an electrode for delivery of radiofrequency current (11) connected to a radiofrequency generator via a connecting wire (42) within said catheter shaft (1); and a solution transport path being in constant communication with an inside of the balloon (6) and connected to a liquid feed pump (29) for feeding a coolant (C).

An Imaging, guidance, planning and treatment system integrated into a single unit or assembly of components, and a method for using same, that can be safely and effectively deployed to treat re-stenosis from m intra vascular location in various medical settings, including in a hospital or in an outpatient setting. The system utilizes the novel process of Radio-Frequency Electrical Membrane Breakdown (EMB or RFEMB) to destroy the cellular membranes of unwanted tissue without denaturing the intracellular contents of the cells comprising the tissue, thus preventing or alleviating re-stenosis after an angioplasty-type procedure. The system preferably comprises at least one EMB treatment catheter-type probe 20, at least one temperature sensor 7, and at least one controller unit for at least partially automating the treatment process.

The present invention discloses medical systems and methods adapted for the delivery of various medical components such as microwave antennas within or on a body for performing one or more medical procedures. Several embodiments herein disclose medical systems comprising a combination of one or more medical components and one or more elongate steerable or non-steerable arms that are adapted to mechanically manipulate the one or more medical components. Several embodiments of microwave antennas are disclosed that comprise an additional diagnostic or therapeutic modality located on or in the vicinity of the microwave antennas.