An automated laser-surgery system for performing a closed-loop surgical procedure is disclosed. The procedure includes forming a post-procedural goal based on a three-dimensional (3D) image of a surgical site, planning a path for a surgical laser signal based on the post-procedural goal, performing a procedural pass by steering the surgical laser signal along the path, measuring the surface of the surgical site after the procedural pass, updating a model based on the measured effect at the surgical site, and evaluating the success of the procedural pass based on the surface measurement and the post-procedural goal. If necessary, a new path is planned based on the post-procedural goal and the surface measurement a new pass based on that path is performed, and the surface is again measured to evaluate the success of the new pass. These operations are repeated as a closed-loop sequence as many times as necessary to achieve success.

A laser system includes a laser source generating a laser beam having ultra-short pulses; a laser delivery assembly optically receiving the laser beam and comprising: a beam splitter configured to split the laser beam between a first beam delivery path and a second beam delivery path; and at least one focusing lens optically coupled to the beam splitter and configured to focus the laser beam from each of the first beam delivery path and the second beam delivery path to a focal point on a predefined plane; wherein the first beam delivery path intersects the predefined plane at a first angle, the second beam delivery path intersects the predefined plane at a second angle, and a first pulse from the first beam delivery path and a second pulse from the second beam delivery path are coincident at the focal point.

A system includes a focus optic configured to converge an electromagnetic radiation (EMR) beam to a focal region located along an optical axis. The system also includes a detector configured to detect a signal radiation emanating from a predetermined location along the optical axis. The system additionally includes a controller configured to adjust a parameter of the EMR beam based in part on the signal radiation detected by the detector. The system also includes a window located a predetermined depth away from the focal region, between the focal region and the focus optic along the optical axis, wherein the window is configured to make contact with a surface of a tissue.

Disclosed is a system provided with cooling fluid for interstitial laser therapy that limits and/or provides control of the laser ablation zone produced by a device for interstitial laser therapy, which allows for better control of the laser ablation zone and more predictive and accurate interstitial laser therapy. The device for interstitial laser therapy includes an optical waveguide having an optical output end and an optical diffuser optically coupled to, optically associated with, or positioned about the optical output end. An irrigation tube directs cooling fluid to flow out of a distal end of the irrigation tube which directs cooling fluid to flow inside of and/or outside of the optical diffuser.

A catheter includes proximal and distal sections, a shaft coupled between the proximal and distal sections, and optical fibers extending through the shaft and to the distal section of the catheter. The distal section includes a support structure that includes a proximal end, a distal end, reflective elements, and a cap disposed over a portion of the distal end of the support structure. The proximal end includes alignment receptacles. Each of the optical fibers is inserted into corresponding ones of the alignment receptacles and the alignment receptacles are shaped to maintain the optical fibers straight in the support structure. The distal end includes orifices facing different directions. Each of the optical fibers is optically aligned with corresponding ones of the lenses, reflective elements, and orifices such that the optical fibers in the support structure are straight. The cap includes optical ports aligned with the orifices.

A phototherapy device 1 includes a laser light source 8 for emitting laser light at a target portion T, a limit switch 10 for detecting an approach of the laser light source 8 to a target portion T up to a predetermined distance and outputting a proximity signal, and an optical sensors 7 for detecting a distance to the target portion T and outputting a distance signal S corresponding to the distance and is configured so that a reference value L0 is set based on the distance signal S detected after the proximity signal is detected and emission of laser light by the laser light source 8 is permitted in accordance with an amount of fluctuation of the distance signal S with respect to the reference value L0.

A treatment support device (1) configured to control therapeutic light irradiated toward a treatment site of a subject (ST) to whom a therapeutic agent containing a fluorescent dye used in photoimmunotherapy has been administered and excite the fluorescent dye by means of the therapeutic light to perform treatment is provided with: a light source (242) for emitting the therapeutic light; a control unit (17) for controlling the irradiation time and the irradiation intensity of the therapeutic light; and a detection unit (182) for detecting the intensity of the fluorescence generated from the fluorescent dye, when the therapeutic light is being emitted. The control unit (17) controls at least one of the irradiation time and the irradiation intensity of the therapeutic light based on the irradiation intensity of the fluorescence.

Various embodiments provide a microwave amplification apparatus for an electrosurgical instrument. The microwave amplification apparatus comprises: a cable assembly; a proximal launch portion, and a distal amplification portion. The proximal launch portion is connected to a proximal end of the cable assembly, and comprises: a DC source configured to launch a DC signal along the cable assembly, and a microwave source configured to launch a microwave signal along the cable assembly. The distal amplification portion is connected to a distal end of the cable assembly, and comprises: a power amplifier configured to receive the microwave signal as an input signal to be amplified. The distal amplification portion is configured to apply the DC signal as a drain voltage across the power amplifier. The power amplifier has an output that is connectable to deliver an amplified microwave signal to a structure that is configured to deliver microwave energy into biological tissue.

An electrosurgical instrument with a radiating tip portion having a relative permeability and/or relative permittivity that is selected to provide an electrical length for the radiating tip portion that enables effective delivery into biological tissue of microwave EM energy supplied thereto, at two or more frequencies of choice. The instrument has a radiating tip portion disposed to receive microwave EM energy from a coaxial cable, the radiating tip portion having a first effective relative permeability at a first frequency and a second effective relative permeability at a second frequency.

Various embodiments provide an electrosurgical instrument comprising: a flexible coaxial transmission line arranged to convey microwave energy; a radiating tip portion connected at a distal end of the flexible coaxial transmission line and configured to receive the microwave energy, the radiating tip portion comprising: a distal coaxial transmission line for conveying the microwave energy; and a needle tip mounted at a distal end of the distal coaxial transmission line, the needle tip being arranged to deliver the microwave energy into biological tissue; and a heat sink mounted at an interface between the flexible coaxial transmission line and radiating tip portion. The heat sink is in thermal communication with a proximal end of the distal coaxial transmission line and configured to draw thermal energy from the radiating tip portion. Also, a maximum outer diameter of the radiating tip portion is smaller than an outer diameter of the flexible coaxial transmission line. An associated electrosurgical system is also disclosed.