An ablation instrument (e.g., an ablation balloon catheter system) includes an elongate catheter having a housing with a window formed therein. An energy emitter is coupled to the elongate catheter and is configured to deliver ablative energy. A controller is received within the window and is coupled to the energy emitter such that axial movement of the controller within the window is translated to axial movement of the energy emitter and rotation of the controller within the window is translated into rotation of the energy emitter. The instrument includes a motor that is at least partially disposed within the housing of the catheter; a first gear that is operatively connected to and driven by the motor; and a second gear that is coupled to the energy emitter and is driven by the first gear to cause rotation of the energy emitter, while allowing the energy emitter to move axially.

A pulse application method includes: setting a wavelength of light within a range in which a temperature rise width of collagen fibers in living tissue when the light is applied to the living tissue is larger than a temperature rise width of water containing cells that are contained in the living tissue and that are present around the collagen fibers; and applying a pulse of light with the set wavelength to the living tissue to heat the living tissue.

A laser lithotripsy system includes a thulium-based laser that, upon activation, selectively produces a continuous wave of laser light with a first wavelength or uniformly spaced, intermittent pulses of laser light with the first wavelength. The system further includes a second laser that, upon activation, produces laser light with a second wavelength, which is shorter than the first wavelength. The system includes an optical detector positioned to receive light emitted by a target in response to the target being impacted by the light produced by the second laser, and a controller communicatively coupled to both the optical detector and the first laser such that the controller selectively activates and deactivates the first laser based on one or more measured characteristics of the light emitted by the target and received by the optical detector.

Dermatological systems and methods for providing a therapeutic laser treatment of tissue having poor chromophore selectivity using a laser source having a grating element to provide laser light having reduced linewidth. In some embodiments, the linewidth is reduced by at least half compared to the linewidth that would be provided in a system without the grating filter element. The linewidth may be reduced in some cases to 500 GHz or less, 300 GHz or less, or 200 Hz or less.

The present invention discloses medical systems and methods adapted for the delivery of various medical components such as microwave antennas within or on a body for performing one or more medical procedures. Several embodiments herein disclose medical systems comprising a combination of one or more medical components and one or more elongate steerable or non-steerable arms that are adapted to mechanically manipulate the one or more medical components. Several embodiments of microwave antennas are disclosed that comprise an additional diagnostic or therapeutic modality located on or in the vicinity of the microwave antennas.

Systems, devices, and methods for identifying a target in vivo are disclosed. A target identification system for use in electrosurgery includes a probe, an optical splitter, and a spectroscopy system. The probe includes an optical pathway to pass a first optical signal to an anatomical target and at least a portion of a second optical signal from the anatomical target. The optical splitter includes a first port to direct the first optical signal to the optical pathway and to receive the at least a portion of the second optical signal from the optical pathway, a second port to receive the first optical signal, and a parabolic reflector to redirect the portion of the second optical signal. The spectroscopy system can identify a characteristic of the anatomical target based on the redirected at least a portion of the second optical signal.

The present disclosure provides a medical device (100) for inducing cell death in cancer cells. The device comprises a signal generator (102) arranged to generate a pulsed electrical signal, and a transmitter (116) arranged to receive the pulsed electrical signal and generate, in response to the electrical signal, an electric field in a treatment volume. The device (100) is arranged such that the pulsed electrical signal received by the transmitter (116) has a pulse width of 0.1 microsecond to 1 millisecond, and a signal frequency of 10 Megahertz to 20 Gigahertz. The present disclosure also provides a method of inducing cell death. The method comprising a step of generating, using a transmitter (116), a pulsed time varying electric field in a treatment volume comprising a volume of cells to be treated. The electric field has a pulse width of 0.1 microsecond to 1 millisecond, and a signal frequency of 10 Megahertz to 20 Gigahertz.

Systems and methods for treating a body region are provided herein. A treatment device for treating a body region is provided, and may include a first applicator and a second applicator. The first and second applicators are held on the body region by a belt. The first applicator may include a first magnetic field generating device and a radiofrequency electrode. The second applicator may include a second magnetic field generating device. The first and second magnetic field generating devices may each generate a time-vary magnetic field with a plurality of sequential magnetic impulses to cause muscle contraction in the body region. The radiofrequency electrode may provide radiofrequency waves causing heating of tissue within the body region. The treatment device may further include an energy storage device and a switching device. The switching device my discharge energy from the energy storage device to the first or the second magnetic field generating device to generate the time-vary magnetic field.

An ablation probe tip 100 having a shaft 102 with an insertion end 104 and an annular aperture 120 near the insertion end 104. A center of ablation 124 is located within the shaft 102 and surrounded by the annular aperture shaft 102. The ablation probe tip 100 may be part of an ablation probe system 50 that includes an ablation source 60 that provides ablation means 62 to the ablation probe tip 100. The center of ablation 124 is a focal region from which the ablation means 62 radiates through the annular aperture 120 to form an ablation zone 150, 160, 170. The system 50 has at least one intra-operative control selected from the group of: ablation zone positioning control, ablation zone shaping control, ablation center control, ablation zone temperature control, guided ablation volume/diameter control, and power loading control.

An energy delivery system comprises a transmission member and an antenna at a distal end of the transmission member. The antenna includes a first conductive arm, an insulator extending around the first conductive arm, and a second conductive arm. The second conductive arm includes a coil. The system also comprises a barrier layer radially spaced from the insulator and surrounding the transmission member and antenna. The barrier layer extends from a proximal portion of the transmission member to a distal portion of the antenna. The system also comprises a jacket surrounding the barrier layer and forming a fluid channel for flow of a cooling fluid.