The present invention relates to systems for use for radio frequency ablation. The systems can include one or more of an ablation tool, power source for use with the ablation tool and a backstop for use in conjunction with the ablation tool during surgical procedures. Preferred ablation tools comprise a series of three or more blade-shaped electrodes disposed in a linear, curved, curvilinear or circular array. The backstops are useful for reducing direct physical and thermal heat transfer injuries to the patient or surgeon during procedures using radiofrequency (RF) ablation devices.

The present invention discloses medical systems and methods adapted for the delivery of various medical components such as microwave antennas within or on a body for performing one or more medical procedures. Several embodiments herein disclose medical systems comprising a combination of one or more medical components and one or more elongate steerable or non-steerable arms that are adapted to mechanically manipulate the one or more medical components. Several embodiments of microwave antennas are disclosed that comprise an additional diagnostic or therapeutic modality located on or in the vicinity of the microwave antennas.

The present disclosure provides systems, devices, and methods for penetrating a biological membrane. The system may comprise a laser unit configured to generate one or more laser beams. The system may comprise a set of targeting optics configured to direct the one or more laser beams to a target region of the biological membrane. The system may comprise a raster scanner operatively coupled to the laser unit and the set of targeting optics. The system may comprise a non-transitory computer readable storage medium comprising a set of instructions. The set of instructions may be configured to control at least one of the laser unit, the set of targeting optics, or the raster scanner to photodisrupt the target region of the biological membrane to a target depth while minimizing damage to one or more blood vessels in proximity to the target region.

The present disclosure is directed to systems, device and methods for cancer ablation treatment of human and animal subjects through the application of a combination of electromagnetic sources, in particular, microwave and radio frequency radiation that are focused on a tumor harboring magnetic or other metallic nanoparticles to result in synergetic heating effect whereby the tumor is heated to ablative temperature due to the strong absorption of the nanoparticles while the surrounding healthy tissue is hardly affected.

There is provided a cutting element for use in a hair cutting device. The cutting element comprises an optical waveguide having a sidewall, wherein a portion of the sidewall forms a cutting face for contacting hair. The optical waveguide includes a plurality of optical structures spaced along its length, the optical structures being configured to reflect light at one or more wavelengths. When broadband light is directed along the optical waveguide the optical waveguide is such that: if the cutting face of the optical waveguide in is not in contact with a target object, then each of the plurality of optical structures reflects light having a first wavelength; and if the cutting face of the optical waveguide is in contact with a target object, then at least one of the optical structures reflects light having a second wavelength different to the first wavelength. A hair cutting device comprising the cutting element and a method of operating the hair cutting device are also provided.

Systems for enabling delivery of very high peak power laser pulses through optical fibers for use in ablation procedures preferably in contact mode. Such lasers advantageously emit at 355 nm wavelength. Other systems enable selective removal of undesired tissue within a blood vessel, while minimizing the risk of damaging the blood vessel itself, based on the use of the ablative properties of short laser pulses of 320 to 400 nm laser wavelength, with selected parameters of the mechanical walls of the tubes constituting the catheter, of the laser fluence and of the force that is applied by the catheter on the tissues. Additionally, a novel method of calibrating such catheters is disclosed, which also enables real time monitoring of the ablation process. Additionally, novel methods of protecting the fibers exit facets are disclosed.

A novel monitoring method evaluates tissue ablation progress. An antenna in a distal portion of an ablation applicator sends and receives electrical information from the target tissue during ablation. The information is used to determine ablation progress. A related ablation monitoring system includes a power monitor and processor operable to evaluate ablation progress based on reflected electrical properties during the ablation. The invention has particular benefits when used in endoscopic-based microwave ablation.

One aspect of the present disclosure relates to a medical laser system, comprising: a first laser source comprising at least a first gain medium for generating a first optical field; and at least one first U-switch configured to control a resonance quality of the first laser source; a control circuit configured to control the first U-switch to cause the first laser source to generate the first optical field as a first pulse train of laser pulses; a second laser source for generating a second optical field as a second pulse train of laser pulses; at least one nonlinear medium for generating a third optical field by a nonlinear interaction between the first optical field and the second optical field; a sensor configured to detect a property of at least one of the optical fields; wherein the control circuit is configured to control operation of the first U-switch so as to adjust a relative timing of the laser pulses of the first pulse train and the laser pulses of the second pulse train responsive to the detected property.

An energy delivery system includes an RF synthesizer circuit configured to generate an RF electric signal and a preamplification stage operably coupled to the RF synthesizer circuit. The preamplification stage has at least one attenuator. A board controller is operably coupled to the attenuator of the preamplification stage that is configured to modify a gain setting of the attenuator. An output connection is configured to provide a low-power signal or a high-power signal based on at least the RF electric signal and the gain setting. The low-power signal or high-power signal is provided to an RF applicator configured to couple an alternating RF electric field to animal tissue.

Catheter for real-time evaluation of duodenal ablation, the catheter including an expandable member configured to stretch the duodenal wall and to generate a fixed distance between a center of the catheter and the duodenal wall; a laser transmitting element coupled with the catheter body and configured to transmit a first laser beam and a second laser beam; wherein the first laser beam is configured to cause ablative damage in a region of the duodenal wall as a result of its impingement thereon, and wherein the second laser beam is configured to detect modifications in the region of the duodenal wall resulting from the impingement of the first laser beam thereon.