Example apparatuses and systems are disclosed for providing controlled delivery of electrolysis products to a site which may be used for treatment of infection and ablation of undesirable cells and tissue. A system disclosed may include a power supply, two electrodes, an aqueous matrix that may close the electric circuit between the electrodes at the treated site, and a controller. The controller may control the electrical circuit to induce a direct current through the electrodes and an aqueous matrix to produce electrolysis products. The duration and magnitude of the charge applied may determine the dose of the products applied to the treatment site. The composition of the electrodes and the aqueous matrix may be chosen to produce desired products. An apparatus is disclosed that may be in the form of a pad for applying to a wound. An apparatus is disclosed that may be used for treating internal tissue.

An electroporation therapy apparatus method, and system is provided. The apparatus, system, and method comprise an electroporation generator (26). The electroporation generator (26) is configured to output an asymmetric balanced waveform to a medical device, and the asymmetric balanced waveform comprises a first positive phase and a first negative phase. The first positive phase comprises a first current and a first time and the first negative phase comprises a second current and a second time. The first current is greater than the second current and the second time is greater than the first time. The asymmetric balanced waveform is configured to irreversibly electroporate a target tissue.

A device for radio frequency ablation, configured to deliver a direct current, an alternating current, and a radio frequency energy to a lesion for treating a pulmonary disease. The device for radio frequency ablation can determine the effectiveness of an ablation according to one or more of a fall in impedance, a rate of change in impedance, a change in the rate of change in impedance, or a change from falling in impedance to rising in impedance. The device for radio frequency ablation uses a segmentation control method and dynamic smoothing for adjusting a radio frequency output power to control an ablation temperature, and the tissue to be ablated is prevented from being quickly heated in short time, to ensure a smooth change in the radio frequency output power in the ablation process. The device for radio frequency ablation further comprises a specific protection mechanism for preventing repeated ablation. The temperature of an ablation site is detected before each ablation, and ablation will not be performed if the temperature of the ablation site is higher than 40° C. to 60° C. Also disclosed is a multi-electrode ablation device comprising the device for radio frequency ablation.

The disclosed systems and methods relate to controlling the application of electrosurgical energy by an electrosurgical instrument. An electrosurgical generator in accordance with the present disclosure includes a processor and a memory storing instructions executable by the processor. The instructions when executed, cause the generator to receive signals from the instrument over time relating to whether tissue is grasped by the instrument, receive an indication to provide an indicated treatment power to the instrument where the indicated treatment power is set by a user, determine based on the signals that tissue is currently grasped and that, for at least a predetermined length of time prior, no tissue had been grasped, and based on the determination, provide a treatment power surge to the instrument for a surge time period. After the surge time period, the generator provides the indicated treatment power to the instrument.

A surgical instrument comprising a shaft and an end effector is disclosed. The end effector is releasably attachable to the shaft by a lock biased into a locked condition to hold the end effector to the shaft.

In one embodiment, a medical system includes a medical instrument includes an elongated shaft having a distal end, at least one cutting element disposed at a distal end of the shaft, a position-tracking transducer disposed at the distal end of the shaft, and electrically insulated from the shaft and the at least one cutting element, and at least one metal coagulation electrode disposed at least partially over the position-tracking transducer, which electrically isolates the at least one metal coagulation electrode from the shaft, a signal generator coupled to apply an electrical current to the at least one metal coagulation electrode, and processing circuitry configured to receive signals generated by the position-tracking transducer, and track a location of the distal end responsively to the received signals.

A system for destroying a cancerous tumor. The system includes an electrical probe, an impedance analyzer device configured to be connected to the electrical probe, a DC voltage generator configured to be connected to the electrical probe, and a processing unit connected to the impedance analyzer device and the DC voltage generator. The electrical probe includes a first electrode including a first electrically conductive needle, a second electrode including a second electrically conductive needle with a nanoporous surface placed inside the first electrode, a first electrically insulating layer placed around the first electrode except a first distal end portion of the first electrode, and a second electrically insulating layer placed between the first electrode and the second electrode. The processing unit configured to perform destroying the cancerous tumor by executing processor-readable instructions utilizing the impedance analyzer device and the DC voltage generator.

A method and device for modulating the autonomic nervous system adjacent a pericardial space to treat cardiac arrhythmia includes a treatment source arranged to supply a treatment medium, a catheter having an end sized for insertion into the pericardial space, a medium delivery assembly having a distal end arranged to be positioned by the catheter into the pericardium, with the distal end of the delivery assembly comprising a delivery tip arranged to extend away from the distal end of the catheter into the pericardial space. A connector operatively couples the delivery tip of the medium delivery assembly to the treatment source, and the delivery tip of the medium delivery assembly including a plurality of delivery points for delivering the treatment medium at a plurality of treatment areas within the pericardial space. The device performs modulation or ablation of the autonomic nervous system at selected treatment areas within the pericardium.

An electrosurgical system includes an electrosurgical generator and an electrosurgical instrument coupleable to the electrosurgical generator. The electrosurgical generator includes a controller, a power supply coupled to the controller, and a power converter coupled to the power supply. The controller is configured to cause the power converter to generate a pulsed electric field configured to electroporate tissue and RF current configured to seal tissue. The electrosurgical instrument includes a pair of opposing jaw members configured to grasp tissue. Each of the pair of opposing jaw members includes an electrically conductive tissue-contacting surface configured to electroporate tissue disposed in proximity to the electrically conductive tissue-contacting surfaces via the pulsed electric field and deliver the RF current to the electroporated tissue to seal the electroporated tissue.

An electrosurgical generator is disclosed. The electrosurgical generator includes: a power supply configured to output DC power; an inverter coupled to the power supply, the inverter including a plurality of switching elements; and a controller coupled to the inverter and configured to signal the inverter to simultaneously generate based on the DC power a radio frequency heating waveform and an electroporation waveform.