An irreversible electroporation and radio frequency ablation (IRE/RFA) generator includes an IRE pulse generator, harmonic filtration circuitry, and a waveform interleaver. The IRE pulse generator is configured to generate biphasic IRE pulses. The harmonic filtration circuitry is configured to convert the IRE pulses into an RF signal. The waveform interleaver, which is configured to receive the IRE pulses and the RF signal and generate an output signal having a composition of the adapted IRE pulses having a final shape and repetition rate, the converted RF sinusoidal signal, or a combined IRE/RFA output signal, by switching between the received IRE square pulses and the received converted RF sinusoidal signal.

The present disclosure provides electroporation systems, methods of controlling electroporation systems to limit electroporation arcs through intracardiac catheters, and catheters for electroporation systems. One method of controlling an electroporation system including a direct current (DC) energy source, a return electrode connected to the DC energy source, and a catheter connected to the DC energy source is disclosed. The catheter has a at least one catheter electrode. The method includes positioning the return electrode near a target location within a body and positioning the catheter electrode adjacent the target location within the body. A system impedance is determined with the return electrode positioned near the target location and the catheter electrode positioned within the body. The system impedance is adjusted to a target impedance to arcing from the catheter electrode.

Apparatus and methods for delivering electromagnetic energy to a patient's tissue and reducing pain experienced by the patient during treatment of the patient's tissue with the delivered electromagnetic energy. The tissue treatment apparatus includes a delivery device configured to transfer the electromagnetic energy through the skin surface to a region of tissue, and also includes a vibration device that is mechanically coupled with the delivery device. The vibration device is configured to transfer mechanical vibrations along an axis substantially normal to the skin surface to the region of tissue being treated.

A portable electrocauter used especially for electrofulguration, electrodesiccation and electrocoagulation contains a source of energy and an applicator. The electrocauter is provided with the source of DC with the maximal current of 1 mA and voltage between 0.8 to 12 kV. The applicator is provided with precisely aiming finish and the patient is conductively connected with the equipment by disposable grounding electrode while the output of the discharge between the working electrode and the surface of the skin is in the range of 0.3 to 4.0 W.

A pulsed field ablation (PFA) system includes a composite electrode, a body-surface electrode, a PFA generator, and a processor. The composite electrode is coupled to a distal end of a catheter configured for insertion into an organ of a patient. The body-surface electrode is configured to be attached to a skin of the patient. The PFA generator is configured to be electrically connected to the composite electrode of the catheter and to the body-surface electrode, and to generate Direct-Current (DC) PFA pulses. The processor is configured to control the PFA generator to apply the DC PFA pulses between the composite electrode and the body-surface electrode while the composite electrode is placed in contact with target tissue of the organ and the body-surface electrode is in contact with the skin of the patient.

A surgical instrument system comprising a first motor, a second motor, and a third motor is disclosed. The surgical instrument system comprises a first handle comprising a first number of controls, a second handle comprising a second number of controls, and a shaft assembly. The shaft assembly is attachable to the first handle in a first orientation in order to engage one of the motors. The shaft assembly is attachable to the second handle in a second orientation to engage a different motor. The surgical instrument system is configured to perform a different function of an end effector in the first orientation and the second orientation.

In one embodiment, a medical system includes a medical instrument includes an elongated shaft having a distal end, at least one cutting element disposed at a distal end of the shaft, a position-tracking transducer disposed at the distal end of the shaft, and electrically insulated from the shaft and the at least one cutting element, and at least one metal coagulation electrode disposed at least partially over the position-tracking transducer, which electrically isolates the at least one metal coagulation electrode from the shaft, a signal generator coupled to apply an electrical current to the at least one metal coagulation electrode, and processing circuitry configured to receive signals generated by the position-tracking transducer, and track a location of the distal end responsively to the received signals.

The present invention provides an electrosurgical generator and an electrosurgical system with variable frequency output. The electrosurgical system with variable frequency output comprises: high frequency electrosurgical instruments and an ultrasonic surgical instrument and the electrosurgical generator, wherein the high frequency electrosurgical instruments and the ultrasonic surgical instrument share one energy output interface or respectively use different energy output interfaces. An energy switching system is further arranged in the electrosurgical generator, can switch an output energy type at any time according to needs, so as to avoid frequent changes of the surgical instruments.

Disclosed herein are apparatus, systems, and methods for ablating tissue in a patient by electroporation. Embodiments generally include an ablation catheter having a hand, a shaft, and an electroporation electrode arrangement. The shaft has a distal end and defines a longitudinal axis of the ablation catheter. The electroporation electrode arrangement is at the distal end of the shaft and is configured to generate a multidirectional electric field when at least one pulse sequence is delivered thereto. The multidirectional electric field includes at least two of the following directions relative to the longitudinal axis: generally axial, circumferential, and transverse. The electroporation electrode arrangement is configured to operatively couple to an electroporation generator that is configured to generate the at least one pulse sequence and is configured to receive the at least one pulse sequence from the electroporation generator.

A method for destroying a cancerous tumor. The method includes putting two electrodes of an electrical probe in contact with a portion of the cancerous tumor, plotting an impedance phase diagram by measuring a set of electrical impedance phase values from the portion of the cancerous tumor at end of a respective set of pre-determined time steps, destroying cancer cells of the portion of the cancerous tumor within each time step of the respective set of pre-determined time steps by electrolyzing peripheral medium surrounding the cancer cells of the portion of the cancerous tumor by applying a direct current (DC) voltage between the two electrodes, and stopping destroying of the cancer cells responsive to a complete destruction of the portion of the cancerous tumor, where the complete destruction includes obtaining a positive slope of the impedance phase diagram (IPS).