Ablation systems and methods of the present disclosure include a catheter including one or more image sensors. The one or more image sensors can facilitate, for example, positioning an ablation electrode at a treatment site of an anatomic structure and, additionally or alternatively, can facilitate controlling delivery of therapeutic energy to a treatment site of an anatomic structure.

Disclosed are a body contouring device using RF energy, a control method thereof, and a body contouring method using the same, in which a surface of tissue overheated due to the edge effect is selectively cooled while the tissue is heated with the RF energy transferred thereto, thereby having a uniform treatment effect on a treatment area, reducing pain, and preventing the tissue from being damaged.

A surgical system for performing a capsulotomy of a lens capsule of an eye includes an elastic ring, a suction cup, an interface, a converter, and a control console. The elastic ring includes a conductive surface. The interface may be coupled to an air port and/or a fluid line of a phacomachine. The converter detects a pulse of air from the phacomachine via the interface, and produce an electrical signal in response. Fluid received from the phacomachine is delivered into the suction cup. The system is configured to remove the fluid from the suction cup and between the suction cup and a surface of the eye to form a suction seal. The control console is configured to, in response to receiving the electrical signal, drive a series of electrical pulses through the conductive surface of the elastic ring, causing the elastic ring to perform a tissue cutting operation.

Systems and methods deploy a therapeutic or diagnostic element into contact with a body tissue region. The systems and methods can sense position of the therapeutic or diagnostic element relative to a targeted tissue region without direct or indirect visualization, by sensing fluid pressure in a fluid path having an outlet located at or near the therapeutic or diagnostic element. The systems and methods can also inflate the therapeutic or diagnostic element during use, while taking steps to avoid over-inflation and/or while dynamically monitoring the pressure conditions within the expanded element.

An electroporation device includes a shaft and a conformable electrode assembly. The shaft includes a proximal end and a distal end, wherein the conformable electrode assembly is located at the distal end of the shaft. The electrode assembly has a first side and a second side, wherein the first side includes a first non-conductive portion and a first electrode centrally located on the first side. The first non-conductive portion is defined by a first surface area and the first electrode is defined by a second surface area, wherein the first surface area is greater than the second surface area.

The present disclosure provides catheter systems, electrode assemblies, and methods for electrically stimulating one or more points about the circumference of the renal artery to provide real time intraprocedural operational feedback to the operator of a renal denervation procedure to allow for more precise and thorough ablation of the renal artery and better patient outcomes. In many embodiments, an electrode assembly is provided that includes multiple splines that extend from an insulated proximal hub to an insulated distal hub and are interconnected to an electrical wire to allow the splines to independently function as electrical stimulation electrodes. The electrically active splines can then be energized at one or more desired points during a renal denervation procedure to provide operational feedback.

The disclosed technology includes couplers, nose pieces, and strain relief hubs for ablation catheter assemblies and methods of using the same. The disclosed technology can include a medical probe having a coupler having a first portion, a second portion, and a vent port. The second portion can slide between a first position and a second position. When in the first position, the vent port can be at least partially obstructed by the first portion and, when in the second position, the vent port can be unobstructed by the first portion. The medical probe can include a nose piece having an outer diameter of less than 0.14 inches and an aperture extending therethrough. The aperture can be sized to receive a catheter. The medical probe can include a strain relief hub having a first portion and a second portion and configured to be coupled to a handle of the medical probe.

Flexible circuit strips of a catheter balloon may comprise a substrate and a contact electrode disposed on the substrate. A cover may be disposed over a peripheral portion of the contact electrode and an adjacent portion of the substrate The cover is intended to increase robustness of the contact electrode in response to fatigue that might arise from repeated expansion and contraction of the catheter balloon.

A catheter balloon comprises an ellipsoidal membrane. A plurality of flexible circuit strips, each of which comprises a substrate and a contact electrode, are disposed about the membrane. A coating is disposed atop at least the outer surface of the membrane and may also be disposed atop a portion of each of the substrates. The coating may comprise a dielectric material, such as parylene. The coating may increase the smoothness of the balloon. When subject to internal pressures that expand the balloon, the coating may also increase the resilience of the balloon relative to a balloon that lacks the coating as determined by changes in the balloon's diameter before and after expansion.

An ablation catheter including an elongate shaft, an inflatable balloon positioned at a distal region of the elongate shaft, a first ablation electrode disposed outside of and carried by an outer surface of the inflatable balloon, a first ultrasound transducer disposed outside of the inflatable balloon, and a flexible circuit. The flexible circuit includes a first conductor and a second conductor and is disposed outside of and carried by the outer surface of the inflatable balloon. The first conductor is in electrical communication with the first ablation electrode, and the second conductor in electrical communication with the first ultrasound transducer.