Neuromodulation catheter systems with controlled irrigation capabilities and methods for using such systems are disclosed herein. One such method includes, for example, positioning an irrigated neuromodulation catheter at a treatment site within a renal blood vessel of a human patient, delivering neuromodulation energy at the treatment site, and delivering irrigation fluid to the treatment site having characteristics coordinated with the delivered energy. The characteristics can be adjusted to maintain an energy delivery element and/or tissue of the blood vessel at a constant temperature as power is increased. The method can further include monitoring at least one parameter of the tissue and/or of the energy delivery element, and adjusting the neuromodulation energy and/or the characteristics of the irrigation fluid if the at least one parameter falls outside of a treatment range of values.

Embodiments of the present invention include a medical probe having a flexible insertion tube, a basket assembly, and a plurality of electrodes. The basket assembly has a proximal end that is connected distally to the insertion tube and includes a plurality of resilient spines, which have respective outer sides and inner sides and are configured to bow radially outward from an axis of the basket assembly and are conjoined at the proximal end and at a distal end of the basket assembly. The plurality of electrodes are fixed to respective ones of the spines in respective longitudinal positions that are staggered on any given spine relative to the longitudinal positions of the electrodes on the spines adjacent to the given spine, and which include a conductive material that is biased towards the respective outer sides of the spines.

A containment bag assembly for extracting a tissue specimen comprises a bag having one or more segmenting wires, an outer tube comprising a proximal and distal end, a flexible ring configured to form a top opening of the containment bag, wherein the flexible ring comprises two ring subassemblies, each having a proximal and distal end, a flexible member positioned between and coupled to the distal ends of the two ring subassemblies, wherein, when the flexible member is in a collapsed position, the two ring subassemblies are in a collapsed position and the containment bag is configured to be stored within the outer tube, and wherein, when the flexible member is in an expanded position, the two ring subassemblies and the flexible member bias the top opening of the containment bag to an open position to enable placement of the tissue specimen within the containment bag.

A tissue segmentation device comprises segmenting wires, a grasper, an introducer tube that is shaped and sized to allow introduction of the segmenting wires and the grasper into a patient incision, a specimen bag configured to be deployed through the introducer tube and into the patient incision, at least one actuator positioned adjacent a proximal end of the introducer tube and coupled to proximal portions of the segmenting wires and the grasper, and wherein the at least one actuator is configured for manipulating the grasper to grasp a tissue specimen prior to or during tissue segmentation, wherein manipulation of the grasper further enables pulling the tissue specimen into the segmenting wires for segmentation, positioning the tissue specimen such that it contacts the segmenting wires, and/or enabling placement of the tissue specimen in the bag.

A system for controlling operation of a radiofrequency treatment device to apply radiofrequency energy to tissue to heat tissue to create lesions without ablating the tissue. The system includes a first treatment device having at least one electrode for applying radiofrequency energy to tissue, a controller including a connector to which a first treatment device is coupled for use, and a generator for applying radiofrequency energy to the electrodes. The controller controls application of energy so that the tissue is thermally treated to create lesions but preventing thermal treatment beyond a threshold which would ablate the tissue.

Embodiments of the present invention include a medical probe having an insertion tube, a basket assembly, an axial electrode, and a plurality of radial electrodes. The insertion tube is configured for insertion into a body cavity of a patient. The basket assembly has a proximal end that is connected distally to the insertion tube and includes a plurality of resilient spines, which are configured to bow radially outward from an axis of the basket assembly and are conjoined at a distal end of the basket assembly. The axial electrode is disposed at the distal end of the basket assembly, having a diameter of at least 1.5 millimeters, and is configured to contact tissue in the body cavity. The plurality of radial electrodes are configured to contact the tissue in the body cavity and include radial electrodes disposed on the spines.

An ablation device and an ablation system provided with an ablation device, include an ablation assembly and an adjustment assembly provided at the proximal end of the ablation assembly. The adjustment assembly includes an outer catheter and an inner catheter which extend axially. The ablation assembly includes a supporting framework and an ablation member provided on the supporting framework. The supporting framework includes a positioning frame and a bearing frame. The positioning frame is provided at the distal end relative to the bearing frame, the distal end of the outer catheter is connected to the proximal end of the bearing frame, the distal end of the inner catheter is connected to the distal end of the positioning frame. During moving of the inner catheter relative to the outer catheter, the supporting framework deforms, and the deformation ratio of the positioning frame is less than that of the bearing frame.

A system for controlling operation of a radiofrequency treatment device to apply radiofrequency energy to tissue to treat tissue to create lesions without ablating the tissue. The system includes a first treatment device having a plurality of electrodes. The electrodes are maintained in axial alignment and fixed radial spacing in retracted and extended positions. The device includes a basket having a plurality of arms. The arms are maintained in a fixed radial spacing in the collapsed position of the basket.

A corrugated radiofrequency ablation catheter having wall-attaching adjustment wires (6, 6A, 6B, 6A′, and 6B′), provided with a strip-shaped connecting catheter, an electrode frame provided at the front end of the connecting catheter, and a control handle (20) provided at the rear end of the connecting catheter. The electrode frame is a corrugated electrode frame consisting of one or more corrugations, where one or more electrodes (2) respectively are distributed on the corrugations. The rear sections of the wall-attaching adjustment wires (6, 6A, 6B, 6A′, and 6B′) are slidably provided within one lumen of the connecting catheter and are connected at the rear extremities (60) onto a control element (22) provided on the control handle (20) or connected onto a control element (22) provided outside of the control handle (20).

An endoscopic medical system can include an endoscopic end effector including three or more jaws. Each of the three or more jaws can respectively include a corresponding electromagnetic energy signal conductor. The end effector can also include two or more jaw linkages, an individual jaw linkage corresponding to a respective one of the jaws, such that at least two of the jaws are configured to move, independent of one another.