A medical device that has a first array of loop electrodes and a second array of loop electrodes. The first array of loop electrodes and the second array of loop electrodes are configured to expand within a uterus and deliver a therapy current to tissue defining the uterus.

An elongate medical device shaft may comprise an elongate body and an annular electrode disposed on the elongate body. The annular electrode may define a longitudinal axis and have an outer diameter. The outer diameter may be greater at an axial center of the electrode than at an axial end of the electrode. Additionally or alternatively, the elongate body may comprise three longitudinal sections having three wall thicknesses. The middle wall thickness may be less than the proximal and distal wall thicknesses and the distal wall thickness may be less than the proximal wall thickness. Additionally or alternatively, the shaft may comprise an inner cylindrical structure and an outer tube. The outer tube may comprise a first radial layer and a second radial layer that is radially-outward of the first radial layer, the first radial layer, second radial layer, and inner structure having different stiffnesses.

A device for therapeutic neuromodulation in a nasal region can include, for example, a shaft and a therapeutic element at a distal portion of the shaft. The shaft can locate the distal portion intraluminally at a target site inferior to a patient's sphenopalatine foramen. The therapeutic element can include an energy delivery element configured to therapeutically modulate postganglionic parasympathetic nerves at microforamina of a palatine bone of the human patient for the treatment of rhinitis or other indications. In other embodiments, the therapeutic element can be configured to therapeutically modulate nerves that innervate the frontal, ethmoidal, sphenoidal, and maxillary sinuses for the treatment of chronic sinusitis.

The present disclosure provides catheters for electroporation systems. One catheter includes a plurality of catheter electrodes disposed along a portion of a distal end of the electroporation catheter. The plurality of catheter electrodes includes a plurality of first type catheter electrodes adapted for use with an electroporation generator during an electroporation procedure and a plurality of second type catheter electrodes adapted for use with an electroporation generator during an electroporation procedure and for use with a diagnostic subsystem. The plurality of first type catheter electrodes is positioned at a distal end of the electroporation catheter. Each second type catheter electrode is adjacent another second type catheter electrode.

A catheter for tissue ablation with one or more electrodes attached to the inner surface of the catheter body facing the lumen, and one or more electrodes attached to the outer surface. The electrodes are offset from the distal end of the catheter. The material between the inner and outer electrodes is an insulator and may be for example a dielectric with a high dielectric constant. This catheter configuration generates an electric field that bends around the tip of the catheter. The field strength near the catheter tip is relatively symmetric; therefore, tissue ablation depth is relatively insensitive to catheter orientation. Embodiments may have multiple inner or outer electrodes and may switch voltage configurations across electrodes to vary the electric field direction over time, improving ablation consistency.

An endocardial catheter comprises an outer shaft having an outer shaft lumen, an inner shaft slidably disposed within the outer shaft lumen, a spline assembly comprising a plurality of flexible splines each having a spline proximal end attached to a distal end of the outer shaft, an opposite spline distal end attached to a distal end of the inner shaft, and an electrode, wherein the plurality of splines collectively define an interior space of the spline assembly, and a foldable membrane disposed within the interior space of the spline assembly, the foldable membrane having an outer edge portion attached to one or more of the splines. The foldable membrane comprises an electrically insulative material.

An instrument may comprise a shaft and an end effector comprising a jaw mechanism coupled to the shaft. The jaw mechanism may comprise a first jaw member and a second jaw member movable relative to one another by pivoting about a pivot axis between an open configuration of the jaw mechanism and a closed configuration of the jaw mechanism. The second jaw member may be rotatable about a roll axis of the second jaw member between at least two orientations, the roll axis of the second jaw member being transverse to the pivot axis. In a first orientation of the at least two orientations, the jaw mechanism is configured to perform a first function. In a second orientation of the at least two orientations, the jaw mechanism is configured to perform a second function differing from the first function.

An irrigated high density electrode catheter can comprise a catheter shaft. The catheter shaft can include a proximal end and a distal end and can define a catheter shaft longitudinal axis. A flexible tip portion can be located adjacent to the distal end of the catheter shaft. An irrigated coupler can be disposed on the distal end of the catheter shaft and can be configured to discharge fluid over the flexible tip portion.

A medical apparatus includes a probe configured for insertion into a body of a patient. The probe includes a plurality of electrodes configured to contact tissue within the body. The medical apparatus further includes an electrical signal generator configured to apply between one or more pairs of the electrodes signals of first and second types in alternation. The signals of the first type include a sequence of bipolar pulses having an amplitude sufficient to cause irreversible electrophoresis (IRE) in the tissue contacted by the electrodes. The signals of the second type include a radio-frequency (RF) signal having a power sufficient to thermally ablate the tissue contacted by the electrodes.

An apparatus includes a catheter shaft assembly and an end effector. The catheter shaft assembly includes an outer sheath with a distal end. The end effector is associated with a distal end of the catheter shaft assembly. The end effector includes a plurality of leaflets. The leaflets are configured to transition between a first configuration and a second configuration. The leaflets are configured to fit within the outer sheath in the first configuration. The leaflets are configured to expand outwardly away from the longitudinal axis in the second configuration in response to being exposed distally relative to the distal end of the outer sheath. Each leaflet includes a flexible body and a plurality of electrodes. Each flexible body defines a plurality of openings. The electrodes are positioned on the flexible body.