Systems, devices, and methods for transvascular ablation of target tissue. The devices and methods may, in some examples, be used for splanchnic nerve ablation to increase splanchnic venous blood capacitance to treat at least one of heart failure and hypertension. For example, the devices disclosed herein may be advanced endovascularly to a target vessel in the region of a thoracic splanchnic nerve (TSN), such as a greater splanchnic nerve (GSN) or a TSN nerve root. Also disclosed are methods of treating heart failure, such as HFpEF, by endovascularly ablating a thoracic splanchnic nerve to increase venous capacitance and reduce pulmonary blood pressure.

Controlling conductive fluid flow during an electrosurgical procedure. At least some of the example embodiments are methods including: flowing conductive fluid from a source lumen to a suction lumen of an electrosurgical wand, the flowing with the electrosurgical wand in a first orientation; sensing a change in orientation of the electrosurgical wand to a second orientation different than the first orientation; and changing a control parameter associated with the conductive fluid flow, the changing responsive to the change in orientation of the electrosurgical wand.

A catheterization system that includes an electrophysiologic (EP) catheter which has a lumen receiving an electrically conductive fluid delivered by a hydraulic line that is acted upon by a peristaltic pump advantageously avoids noise in intracardiac ECG signal recordings by using an electrical connection to short triboelectrical charge carried by the conductive fluid in the hydraulic line to an existing analog ground in the system. In one embodiment, the electrical connection includes an electrically conductive wire housed in the control handle and configured to provide electrical connection between the fluid and a pin on a printed circuit board housed in the control handle that is electrically connected to the analog ground. In another embodiment, the electrical connection shorts the electrically conductive fluid proximal of the control handle of the catheter.

A treatment instrument includes a probe including a treatment portion which treats a treatment target part by ultrasonic vibration, and a back portion provided on a side opposite to the treatment portion. The treatment instrument includes a hollow sheath which surrounds the probe, the sheath having a cutout made to expose the treatment portion. The treatment instrument includes protrusion which is provided in the sheath to cover the back portion on a side opposite to the cutout and which has dimensions smaller than the dimensions of the probe in a direction that intersects with a central axis of the probe.

The present invention relates to a catheter (20) adapted for open-loop irrigated ablation, such as RF ablation, of a tissue (40). Said catheter has a distal tip (22) with an ablation entity (15) adapted for performing ablation of the tissue, an irrigation hole (21) and an ultrasound transducer (5) adapted for transmitting and/or receiving ultrasonic waves. The ultrasound transducer is disposed behind or in the irrigation hole of the catheter, so as to allow an irrigation fluid to flow out of the irrigation hole, and so as to allow transmitting and/or receiving the ultrasonic waves through the irrigation hole. The invention also relates to an imaging system and to a corresponding method for operating a catheter.

An electrosurgical wand. At least some of the illustrative embodiments are electrosurgical wands configured as a surgical forceps including opposed legs that defines respective distal end portions, the legs of the forceps operable to be actuated between an open position and a closed position, an active and return electrode disposed on one of the respective distal end portions, a discharge aperture on one of the distal end portions coupled to a first fluid conduit, and an aspiration aperture through the return electrode on the other of the distal end portions fluidly coupled to a second fluid conduit. In embodiments, the position of the forceps' legs, and the electrical energy applied to the electrodes, is adjusted to provide dissection or coagulation to the tissue. A stop or latch on the forceps' legs may maintain the active and return electrode a fixed distance from one another.

Targeted ablation of parathyroidal tissue is provided through hyperthermia adjuvant therapy. An in situ localization of parathyroidal tissue is obtained. A temperature-sensitive adjuvant is instilled into the parathyroidal tissue. Hyperthermia is therapeutically induced within the parathyroidal tissue. Heat-inducing energy is targeted into the parathyroidal tissue, which selectively includes the temperature-sensitive adjuvant. Application of the heat-inducing energy to the parathyroidal tissue is continued over a therapeutic range. In a further embodiment, the targeted ablation of the parathyroidal tissue is provided through hypothermia adjuvant therapy with the targeted use of cold-inducing energy.

An electrosurgical instrument is provided for the treatment of tissue, the instrument (3) including a shaft (14) and a tip portion including at least one electrode (16), located at the distal end of the shaft. A fluid impermeable sheath (25) covers at least a proportion of the shaft and extends to the tip portion where it terminates in a distal end portion (26). A metallic shroud (29) is provided, comprising an annular ring portion (30) and a rearwardly extending cylindrical portion (31). The ring portion (30) is connected to the tip portion, and the cylindrical portion (31) overlies the distal end portion (26) of the sheath (25) so as to prevent ingress of fluids at the distal end portion of the sheath.

The invention relates to a tissue ablation system including an ablation device having a deployable applicator head configured to be delivered to a tissue cavity and ablate marginal tissue surrounding the tissue cavity. The deployable applicator head is configured to be delivered to a tissue cavity while in a collapsed configuration and ablate marginal tissue surrounding the tissue cavity while in an expanded configuration.

In one aspect, a fixed position RF electrode for conducting surgical procedures, includes a main device body detachably connectable to an RF generating system, a first polarized conductor and a second oppositely polarized conductor, a bipolar electrical conduit passing through the main device body that passes RF energy from the RF generating system to the first polarized conductor and the second oppositely polarized conductor, and a bipolar electrode for contacting a surgically operative material.