System and methods for channeling a path into bone include a trocar having a proximal end, distal end and a central channel disposed along a central axis of the trocar. The trocar includes a radial opening at or near the distal end of the trocar. The system includes a curveable cannula sized to be received in the central channel, the curveable cannula comprising a curveable distal end configured to be extended laterally outward from the radial opening in a curved path extending away from the trocar. The curveable cannula has a central passageway having a diameter configured allow a probe to be delivered through the central passageway to a location beyond the curved path.

A multi-cannula surgical instrument (1), having an inner cannula (3) movably disposed within an outer cannula (2), the inner cannula (3) having a blunt distal tip (3b), one or more first inner ducts (31) and one or more first flow-through orifices (32) arranged to allow one or more fluid flows therethrough, where the inner and the outer cannula (2, 3) at the proximal ends (2a, 3a) thereof are mounted onto a hub (4) that includes a biasing mechanism (43) coupled to the inner cannula (3) and arranged to bias the inner cannula (3) automatically from a retracted towards an advanced position in case of absence of resistance against the inner cannula (3), where the outer cannula (2) has one or more second flow-through orifices (22) that are in fluid communication with one or more second ducts (21) arranged between the outer and the inner cannula (2, 3), where the second flow-through orifices (22), the hub (4) and the second duct(s) (21) are configured to allow at least one fluid flow therethrough.

The present invention relates to comprehensive systems, devices and methods for delivering energy to tissue for a wide variety of applications, including medical procedures (e.g., tissue ablation, resection, cautery, vascular thrombosis, treatment of cardiac arrhythmias and dysrhythmias, electrosurgery, tissue harvest, etc.). In certain embodiments, systems, devices, and methods are provided for delivering energy to difficult to access tissue regions (e.g. peripheral lung tissues), and/or reducing the amount of undesired heat given off during energy delivery.

A system to be used in a tumor treatment, comprises a trocar, a device and connection cables. A trocar that is used to puncture a patient's body at entry site to a tumor location, comprises a first portion with a cutting edge and a heat generating element, an elongated body and a second portion. A device that is connected to a trocar to provide a heat generating element of a trocar with a necessary energy. A device has a radiofrequency current generator to supply and control the energy supplied to a heat generating element.

In operation, there are two steps, in a first step, a trocar is inserted into a tumor location, then a salty solution is pump within a tumor area via a syringe and oblique ports of a heat generating element to cause tumor's cells to shrink. Then after a shrink effect a salty solution is sucked via a syringe. In a second step of operation, a higher temperature may be achieved in cancer cells via the activation of a heat generating element to produce a precise and adequate temperature intracellularly to kill cancer cells.

Embodiments include a method comprising determining histological factors at a target site of a subject, and determining parameters of a fractional resection based on the histological factors. The parameters include dimensionality of a fractional field, orientation of the fractional field, resection depth, and a vector of directed closure. The method includes configuring a cannula assembly for the fractional resection that includes a procedure to generate a fractional field at the target site by fractionally resecting tissue according to the parameters. The fractional resection includes applying a cannula array of the cannula assembly to the target site, and rotating at least one cannula of the cannula array to circumferentially incise and remove a plurality of skin plugs in the fractional field.

Embodiments include a system comprising a cannula assembly configured for rotational fractional resection (RFR). The cannula assembly includes at least one cannula configured for rotational operation and enclosed in a depth guide configured to control an insertion depth of the at least one cannula. The depth guide includes a vacuum chamber configured to maintain vacuum to evacuate resected tissue generated by the RFR.

Embodiments include a system comprising a carrier and a cannula assembly. The carrier includes a proximal end and a distal end, and the proximal end is configured to removeably couple to a remote console. The cannula assembly, which is configured to removeably couple to the distal end of the carrier, is configured for rotational fractional resection (RFR) and includes at least one cannula rotatably coupled to the carrier and enclosed in a depth guide configured to control an insertion depth of the at least one cannula. The depth guide includes a vacuum chamber configured to form vacuum to evacuate resected tissue generated by the RFR.

Systems and methods for ablating tissue in the living body can include a cool electrode.

The present invention relates to comprehensive systems, devices and methods for delivering energy to tissue for a wide variety of applications, including medical procedures (e.g., tissue ablation, resection, cautery, vascular thrombosis, treatment of cardiac arrhythmias and dysrhythmias, electrosurgery, tissue harvest, etc.). In certain embodiments, systems, devices, and methods are provided for delivering energy to difficult to access tissue regions (e.g. peripheral lung tissues), and/or reducing the amount of undesired heat given off during energy delivery.

Methods and systems for modulating intraosseous nerves (e.g., nerves within bone) are provided. For example, the methods and systems described herein may be used to modulate (e.g., denervate, ablate) basivertebral nerves within vertebrae. The modulation of the basivertebral nerves may facilitate treatment of chronic back pain. The modulation may be performed by a neuromodulation device (e.g., an energy delivery device).