A light based treatment device comprises an optical arrangement at a light exit end of an optical fiber. The optical arrangement includes a master oscillator power amplifier based on a semiconductor optical laser and a crystal optical amplifier. In this way, the peak power provided along the optical fiber can be reduced to prevent damage to the optical fiber, while enabling a sufficiently high pulse power to be delivered for tissue treatment.

A tissue-treating portion of a surgical instrument includes a body defining a cavity and a light-energy transmissible sphere captured within the cavity such that a portion of the light-energy transmissible sphere protrudes from the body. The light-energy transmissible sphere is capable of unlimited rotation in all directions relative to the body. The light-energy transmission cable extends through the body to a position spaced-apart from the light-energy transmissible sphere. The light-energy transmission cable is configured to transmit light energy to the light-energy transmissible sphere. The light-energy transmissible sphere, in turn, is configured focus the light energy towards tissue to treat tissue.

Aspects of the present disclosure are directed to, for example, a method of changing operational parameters of a laser probe. The method including the steps of recognising a connection pattern between the laser probe and a battery, setting the laser probe in a programmable mode, and receiving instructions for changing the operational parameters of the laser probe.

The presently disclosed subject matter provides techniques for inducing collagen cross-linking in human tissue, such as cartilage, by inducing ionization of the water contained in the tissue to produce free radicals that induce chemical cross-linking in the human tissue. In an embodiment, a femtosecond laser operates at sufficiently low laser pulse energy to avoid optical breakdown of the tissue being treated. In an embodiment, the femtosecond laser operates in the infrared frequency range.

A light radiating device (1A) performs solidification or cauterization of a biological tissue (PL) by radiating a light beam (BM). A light source (10A) emits the light beam (BM). An optical waveguide (20A) is a member being provided with a reflection surface (21A) totally reflecting the light beam (BM) on an inner circumferential side wall, causing the light beam (BM) emitted from the light source (10A) to enter a part enclosed by the inner circumferential side wall from one end, and sending the light beam (BM) to the other end. A catoptric system (30A) reflects the light beam (BM) sent to the other end of the optical waveguide (20A) and condenses the light beam (BM) on the biological tissue (PL).

The present invention generally relates to an image-guided laser irradiation device for targeted ablation, stimulation, molecular delivery and therapy. Specifically, the invention relates to application of the device in therapies needing precise and targeted removal of a sample, or delivery of impermeable molecules for therapeutic outcome. More specifically, the invention relates to the application of the device in the therapy of visual disorders.

The infrared denaturing device of the present invention is provided with: an infrared lamp which emits infrared light; a light guide which guides the infrared light; and a light projecting body which radiates the infrared light guided from the light guide onto an object to be denatured. The light projecting body is provided with: a reflecting surface which reflects the infrared light; and a radiating surface which radiates the infrared light reflected by the reflecting surface onto an object to be irradiated. Further, there is also provided a denaturing detection sensor which detects denaturing, by means of the infrared light, of a region being denatured.

Methods and apparatus for dermatological laser treatment, e.g. for the removal of unwanted tattoos or other skin pigmentation. Removal of multiple colors with a single pulsed laser beam may be achieved using intensities in excess of about 50 GB/cm.sup.2. Methods for reducing the pain and tissue damage associated with laser tattoo removal include using a spot size of less than 2 mm with a fluence in the range of 0.5-10 J/cm.sup.2. Scanning the laser beam over an area of skin to be treated allows such areas to be treated accurately with scanning patterns calculated to promote rapid dissipation of heat away from treated portions of the skin. Multiple treatment rooms may be served by a single pulsed treatment laser by beam toggling, splitting or pulse-picking to minimise downtime of the laser.

A system includes a focus optic configured to converge an electromagnetic radiation (EMR) beam to a focal region located along an optical axis. The system also includes a detector configured to detect a signal radiation emanating from a predetermined location along the optical axis. The system additionally includes a controller configured to adjust a parameter of the EMR beam based in part on the signal radiation detected by the detector. The system also includes a window located a predetermined depth away from the focal region, between the focal region and the focus optic along the optical axis, wherein the window is configured to make contact with a surface of a tissue.

Methods and devices for an optical assembly for a laser generator comprise: a laser source producing a first beam of light and an optical assembly. The optical assembly comprises a prism. The prism has a bottom surface configured to receive a first beam at an incoming angle of incidence relative to a first surface normal, and a hypotenuse surface configured to transmit, at an exit angle relative to a second surface normal, a second beam having a second aspect ratio. The optical assembly further comprises a plano-convex lens configured to transmit the second beam to a coupler. The coupler comprises a first coupling plane at a first distance from the plano-convex lens and a second coupling plane at a second distance from the plano-convex lens. The combination of the prism and the plano-convex lens is configured to change the beam divergence, so that the first coupling plane has a third aspect ratio and the second coupling plane has a fourth aspect ratio.