A method for preventing undesired tissue coagulation or sloughing during a laser ablation or vaporization procedure involves setting a predetermined usage limit based on objective criteria indicative of wear and/or debris accumulation on a catheter or sleeve through which a surgical laser is fired, and replacing or re-positioning the catheter or sleeve when the predetermined usage limit is exceeded.

The present invention provides an electromagnetic wave therapy device and an immunotherapy method thereof, which sense an ambient temperature and a body temperature of a patient by a sensing unit, thereby generating a sensing signal. A control unit, based on indication information, sensing signals and finding a corresponding spectrum indication signal in the database. The baseband unit in the treatment device generates the therapeutic spectrum content corresponding to different waveforms, frequencies, amplitudes or timetable according to the therapeutic spectrum content, and then uses a radio frequency unit emitting a millimeter-wave at a frequency between 56 GHz and 65 GHz to become a millimeter-wave irradiation source, radiates a patient with a desired location to be treated, and allows the patient to perform a millimeter-wave immunotherapy program by radiating the millimeter-wave treatment device with a non-invasive way to achieve the body's immune cells performance of the purpose and to control and change the human immune system.

A laser pulse energy control system which includes a laser source and a beam divider positioned to receive a calibration laser pulse produced by the laser source. The beam divider reflects a first portion of the calibration laser pulse along a first optical path toward a first plane and transmits a second portion of the calibration laser pulse along a second optical path toward a second plane. An energy meter determines an energy of the first portion of the calibration laser pulse at the first plane and a fluence profiler determines a fluence profile of the second portion of the calibration laser pulse at the second plane. The processor controls an energy of an ablation laser pulse produced by the laser source based on the fluence profile of the second portion of the calibration laser pulse and the energy of the first portion of the calibration laser pulse.

A system, method, and storage device storing computer executable instructions for use in tissue analysis and therapy. An optical probe array has at least two or more optical probes for illuminating tissue and generates light fluorescence and/or diffuse reflectance signals corresponding to the illuminated tissue. One or more ultrasound, CT and MRI imaging guidance systems identify the position of the optical probes relative to the tissue. The imaging guidance system can also be a fusion of an MRI or CT image provided by the MRI or CT imaging guidance system and an ultrasound image provided by the ultrasound imaging guidance system. An imaging system generates a three-dimensional image of the tissue based on the generated light signals and the identified position of the optical probes.

Devices and methods are provided for performing procedure on tissue with flow monitoring using flow sensors. The devices include an elongated member, and at least one flow sensor disposed on the elongated member. The flow sensor includes at least one temperature sensor and at least one heating element having a cavity. At least a portion of the at least one temperature sensor is housed in the cavity. A temperature measurement of the temperature sensor provides an indication of the flow rate of a fluid proximate to the flow sensor.

Devices and methods are provided for performing procedure on tissue with flow monitoring using flow sensors. The devices include an elongated member, and at least one flow sensor disposed on the elongated member. The flow sensor includes at least one temperature sensor and at least one heating element having a cavity. At least a portion of the at least one temperature sensor is housed in the cavity. A temperature measurement of the temperature sensor provides an indication of the flow rate of a fluid proximate to the flow sensor.

A method and system for thermal and non-thermal laser treatments includes a visible laser source. A laser beam in the visible spectrum is generated by the visible laser source and produces a modulated laser output. Laser controls allows the user to generate the pulsed output with variable pulse characteristics to provide selective, localized and user controlled thermal and or non-thermal biological effects at a targeted tissues. This laser system modulates the delivered laser energy to produce accurate and selective targeting of the pigmented cells of the treated tissues to induce therapeutic effects via gentle warming of the cells without significant collateral damage to surrounding tissues.

In one embodiment, a handheld laser treatment apparatus comprises: a handset including a treatment chamber, the treatment chamber having an open treatment aperture; a laser array arranged to project optical energy into the treatment chamber and coupled to a power source; at least one vacuum channel positioned within the treatment chamber and coupled to a vacuum source; a trigger sensor coupled to logic that controls activation of the laser array and the vacuum channel; an attachment sensor arranged to detect which of a plurality of attachments are inserted into the treatment chamber through the treatment aperture. The logic enables activation of the vacuum channel when the attachment sensor detects a first attachment of the plurality of attachments inserted into the treatment aperture. The logic disables activation of the vacuum channel when the attachment sensor detects a second attachment of the plurality of attachments inserted into the treatment aperture.

A lithotripsy or other medical laser treatment system can include a lateral actuator to laterally displace a distal portion of a laser fiber, such as can be scanned or otherwise controlled to generate a spatial or spatiotemporal sub-targeting pattern without requiring laterally moving an endoscope carrying the laser fiber in a longitudinal passage such as a working channel. A targeted stone can be selectively weakened along the pattern, such as using lower energy pulses, before being fragmented, such as by a higher energy shock pulse.

A lithotripsy or other medical laser treatment system can include a lateral actuator to laterally displace a distal portion of a laser fiber, such as can be scanned or otherwise controlled to generate a spatial or spatiotemporal sub-targeting pattern without requiring laterally moving an endoscope carrying the laser fiber in a longitudinal passage such as a working channel. A targeted stone can be selectively weakened along the pattern, such as using lower energy pulses, before being fragmented, such as by a higher energy shock pulse.